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Small molecule cognitive enhancer reverses age-related memory decline in mice

eLife(2020)10.7554/elife.62048Source: DataRank Database

Small molecule cognitive enhancer reverses age-related memory decline in mice is a research paper published in eLife (2020). On theSindex it has a DataRank of 0. It has been cited 176 times.

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Open Access176 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)OA: goldTopics (125)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)Annotations (2)SDGs (1)

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Accessible (1/2)

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Interoperable (2/2)

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Authors (12)

Amber Nolan ORCID,Elma S. Frias ORCID,Morgane Boone ORCID,Gonzalo Ureta ORCID,Katherine Grue

Live enrichment

PubMed:33258451 PMC:PMC7721440

National Institute on Aging

Grant: F32AG054126

National Institutes of Health

Grant: R01AG056770

National Center for Advancing Translational Sciences

Grant: TL1 TR001871

National Institute of Neurological Disorders and Stroke

Grant: K08NS114170

UCSF Foundation

Grant: Weill Innovation Award

National Institute of General Medical Sciences

Grant: R25GM056847

National School Foundation

Grant: Graduate Fellowship Program

Programa de Apoyo a Centros con Financiamiento Basal

Grant: AFB 170004

National Institutes of Health

Grant: 3P30CA082103-21S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5R25GM056847-10

Biomedical Science Research Career Enhancement Program

National Institutes of Health

Grant: 5R01AG056770-03

Aging exacerbates trauma-induced immune pathways and neuronal dysfunction

National Institutes of Health

Grant: 7K08NS114170-03

Cortical Somatostatin Interneuron Dysfunction after Trauma: Role in Cognitive Flexibility

National Institutes of Health

Grant: 5F32AG054126-02

Impact of aging on immune activation and cognitive decline after traumatic brain injury

National Institutes of Health

Grant: 5TL1TR001871-02

NRSA Training Core

Howard Hughes Medical Institute

goldLicense: cc-by

publisherhttps://doi.org/10.7554/elife.62048

publisherhttps://cdn.elifesciences.org/articles/62048/elife-62048-v2.pdf

publisherhttps://cdn.elifesciences.org/articles/62048/elife-62048-v2.xml

publisherhttps://elifesciences.org/articles/62048

repositoryhttps://escholarship.org/content/qt0z71k3js/qt0z71k3js.pdf?t=qmgonu

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciencesAcetamidesActivating Transcription Factor 4AgingAnimalsBrainCognitive DysfunctionCyclohexylaminesDendritic SpinesFemaleHippocampusMaleMemoryMiceMice, Inbred C57BLNeuronsNootropic AgentsSpatial LearningStress, Physiological

MeSH Terms

BrainHippocampusNeuronsDendritic SpinesAnimalsMice, Inbred C57BLMiceAcetamidesCyclohexylaminesNootropic AgentsMemoryAgingFemaleMaleActivating Transcription Factor 4Stress, PhysiologicalSpatial LearningCognitive Dysfunction

Keywords

AgingMemoryMouseNeuroscienceImmune DysfunctionIsrMaleInbred C57BL (mesh)NeurodegenerativeAcquired Cognitive Impairment (rcdc)Aging (mesh)Alzheimer's DiseaseInbred C57BLHippocampusActivating Transcription Factor 4 (mesh)Aging (rcdc)MiceBrain Disorders (rcdc)Cognitive Dysfunction (mesh)31 Biological sciences (for-2020)AcetamidesDementia (rcdc)Animals (mesh)Biology (General)32 Biomedical and Clinical Sciences (for-2020)Male (mesh)Neurosciences (rcdc)Nootropic AgentsNeurodegenerative (rcdc)NeuronsCyclohexylaminesAlzheimer's Disease (rcdc)3 Good Health and Well Being (sdg)QRMice (mesh)BrainBiological sciencesDendritic Spines (mesh)Acetamides (mesh)NeurologicalCyclohexylamines (mesh)MedicineMental healthFemaleBehavioral and Social Science (rcdc)570QH301-705.51.1 Normal biological development and functioningPhysiologicalScienceDendritic Spines0601 Biochemistry and Cell Biology (for)Spatial Learning610StressBrain (mesh)42 Health sciences (for-2020)Stress, PhysiologicalBehavioral and Social ScienceAcquired Cognitive ImpairmentGeneticsPhysiological (mesh)AnimalsCognitive Dysfunction1.1 Normal biological development and functioning (hrcs-rac)Neurons (mesh)Biomedical and Clinical SciencesGenetics (rcdc)Neurological (hrcs-hc)Spatial Learning (mesh)NeurosciencesAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)Health sciencesNootropic Agents (mesh)Activating Transcription Factor 4Brain DisordersMental health (hrcs-hc)Mice, Inbred C57BLGood Health and Well BeingFemale (mesh)DementiaAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) (rcdc)Biochemistry and Cell BiologyHippocampus (mesh)Memory (mesh)

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

10.6084/m9.figshare.24002714.v1figshare

Additional file 1 of APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

10.6084/m9.figshare.24002714figshare