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Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study

eLife(2021)10.7554/elife.70393Source: DataRank Database

Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study is a research paper published in eLife (2021). On theSindex it has a DataRank of 0.713. It has been cited 12 times, with 12 citing works in its 1-hop citation network.

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0.713DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access12 citations · 12 citing works in its network

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Linked data & code

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE176156 GSE18323 GSE89292 GSE103401 GSE102288 GSE107672
ClinicalTrials.govNCT00866619

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 1.71)OA: goldTopics (78)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 54%Citation Network 46%

Base Score Contribution

0.385

From this paper's citation signal

Citation Network Contribution

0.329

From 10 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 12 citers.

Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination
Nature Immunology2022143 citations45 referencesContributes 0.110
The RTS,S malaria vaccine: Current impact and foundation for the future
Science Translational Medicine202250 citations50 referencesContributes 0.079
Predictive signatures of immune response to vaccination and implications of the immune setpoint remodeling
mSphere20256 citations43 referencesContributes 0.045
Targeting type I regulatory T cells to enhance anti-parasitic T helper 1 and T follicular helper cell responses in human malaria
medRxiv20256 citations53 referencesContributes 0.037
Acute and persistent responses after H5N1 vaccination in humans
Cell Reports202411 citations84 referencesContributes 0.030

Authors (27)

Jason Carnes ORCID,William Chad Young,Lindsay N. Carpp ORCID,Stephen De Rosa,Joseph J Campo

Live enrichment

PubMed:35060479 PMC:PMC8782572 OpenAlex:https://openalex.org/W4205306942

National Institute of Allergy and Infectious Diseases

Grant: R01AI095789

National Institute of Allergy and Infectious Diseases

Grant: U19AI128914

PATH Malaria Vaccine Initiative

Grant: Research Contract

Instituto de Salud Carlos III

Grant: PI11/00423

National Institute of Allergy and Infectious Diseases

Grant: U19AI110818

Departament de Salut, Generalitat de Catalunya

Grant: SLT006/17/00109

Instituto de Salud Carlos III

Grant: PI14/01422

Bill and Melinda Gates Foundation

Grant: INV-008576/OPP1154739

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Grant: RYC-2008-02631

Instituto de Salud Carlos III

Grant: CD010/00156

Gates Foundation

Grant: INV-008576

National Institutes of Health

Grant: 1R01AI095789-01A1

Understanding RTS,S malaria vaccine-induced protection through integrated analysi

National Institutes of Health

Grant: 2U19AI110818-06

Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations

National Institutes of Health

Grant: 5U19AI128914-05

Immune Responses to Malaria and HIV Infection and Immunization

FWCI

1.71

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: public-domain

journalhttps://doi.org/10.7554/elife.70393

publisherhttps://doi.org/10.7554/elife.70393

publisherhttps://cdn.elifesciences.org/articles/70393/elife-70393-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/70393/elife-70393-v1.xml

publisherhttps://elifesciences.org/articles/70393

Fields of Study

Malaria Research and ControlMosquito-borne diseases and controlImmune responses and vaccinations0301 basic medicine03 medical and health sciences0303 health sciencesAntibodies, ProtozoanAntigens, ProtozoanB-LymphocytesCase-Control StudiesChild, PreschoolClinical Trials, Phase III as TopicHumansInfantLeukocytes, MononuclearMalaria VaccinesMalaria, FalciparumMozambiqueT-LymphocytesTanzaniaTranscriptomeVaccines, Synthetic

MeSH Terms

Antibodies, ProtozoanAntigens, ProtozoanB-LymphocytesChild, PreschoolHumansInfantLeukocytes, MononuclearMozambiqueT-LymphocytesTanzaniaVaccines, SyntheticCase-Control StudiesMalaria, FalciparumClinical Trials, Phase III as TopicMalaria VaccinesTranscriptome

Keywords

MalariaChristian ministryGovernment (linguistics)Tropical medicineMalaria vaccineBasic researchCoronavirus disease 2019 (COVID-19)HumanMicrobiologyPlasmodium falciparumVaccineInfectious diseaseInflammationimmunologyGene ExpressionImmune Cell ResponsesQH301-705.5ScienceT-LymphocytesAntibodies, ProtozoanAntigens, ProtozoanTanzaniaImmunology and InflammationMalaria VaccinesHumansBiology (General)Malaria, FalciparumMozambiqueB-LymphocytesVaccines, SyntheticQRInfantAntibodies, Protozoan/immunology; Antigens, Protozoan/immunology; B-Lymphocytes/immunology; B-Lymphocytes/metabolism; Case-Control Studies; Child, Preschool; Clinical Trials, Phase III as Topic; Humans; Infant; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/metabolism; Malaria Vaccines/immunology; Malaria, Falciparum/immunology; Malaria, Falciparum/prevention & control; Mozambique; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; Tanzania; Transcriptome/genetics; Transcriptome/immunology; Vaccines, Synthetic/immunology; Plasmodium falciparum; gene expression; human; immune cell responses; immunology; infectious disease; inflammation; malaria; microbiology; vaccineClinical Trials, Phase III as TopicCase-Control StudiesChild, PreschoolLeukocytes, MononuclearMedicineTranscriptome

Sustainable Development Goals

SDG 3: 3. Good health