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Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae

eLife(2022)10.7554/elife.74437Source: DataRank Database

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae is a research paper published in eLife (2022). On theSindex it has a DataRank of 0.459. It has been cited 10 times, with 10 citing works in its 1-hop citation network.

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0.459DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access10 citations · 10 citing works in its network

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Linked data & code

pdb

Data availability

Repositories this paper deposited data in (declared in PubMed).

Dryad10.5061/dryad.8931zcrrz

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)OA: goldTopics (40)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 78%Citation Network 22%

Base Score Contribution

0.360

From this paper's citation signal

Citation Network Contribution

0.0991

From 6 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 10 citers.

Dephosphorylation of the pre-initiation complex is critical for origin firing
Molecular Cell202210 citations57 referencesContributes 0.042
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint
Open Biology20228 citations93 referencesContributes 0.024
Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae.
CUNY Academic Works (City University of New York)20229 citations113 referencesContributes 0.020
CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the Timing of Mitotic Entry and Progression
Biology20235 citations146 referencesContributes 0.012
Roles of phosphatases in eukaryotic DNA replication initiation control
DNA repair20225 citations160 referencesContributes 0.011

Authors (8)

Mihkel Örd ORCID,Andriele Silva,Shaneen Singh ORCID,John F.X. Diffley ORCID,Dirk Remus ORCID

Live enrichment

PubMed:35142288 PMC:PMC8830886

PSC-CUNY Enhanced Award

Grant: 64657-00 52

National Institute of General Medical Sciences

Grant: R01-GM127428

National Institute of General Medical Sciences

Grant: R01-GM107239

National Institutes of Health

Grant: P30 CA008748

European Research Council

Grant: 649124

Biological signal processing via multisite phosphorylation networks

Centre of Excellence for 'Molecular Cell Technologies'

Grant: TK143

Estonian Research Council

Grant: PRG550

Francis Crick Institute

Grant: FC001066

The Francis Crick Institute

Grant: 10668

NIGMS NIH HHS

Grant: R01 GM107239

Wellcome Trust

Grant: 106252/Z/14/Z

Wellcome Trust

Grant: 219527/Z/19/Z

The Francis Crick Institute

Grant: 10066

NIGMS NIH HHS

Grant: R01 GM127428

NIGMS NIH HHS

Grant: SC1 GM121242

The Francis Crick Institute

Grant: CC2002

National Institutes of Health

Grant: 5R01GM127428-04

Molecular mechanisms of replication-coupled chromatin assembly

National Institutes of Health

Grant: 5R01GM107239-08

Mechanism of DNA replication initiation in Saccharomyces cerevisiae

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

Cancer Research UK

Medical Research Council

goldLicense: cc-by

publisherhttps://doi.org/10.7554/elife.74437

publisherhttps://cdn.elifesciences.org/articles/74437/elife-74437-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/74437/elife-74437-v1.xml

publisherhttps://elifesciences.org/articles/74437

repositoryhttps://doaj.org/article/e70ef1cf97474ef78ed6b80699e78c6c

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Saccharomyces cerevisiaeCell Cycle ProteinsSaccharomyces cerevisiae ProteinsMitosisDNA ReplicationPhosphorylationCyclin-Dependent Kinase Inhibitor ProteinsProtein Tyrosine PhosphatasesProtein Phosphatase 2

Keywords

Cell biologyDNA replicationS. cerevisiaePhosphatasePp2aCdc6Cdc55Cdc14Model organismsSaccharomyces cerevisiae ProteinsQH301-705.5ScienceMitosisCell Cycle ProteinsSaccharomyces cerevisiaeBiochemistry & ProteomicsProtein Phosphatase 2Biology (General)PhosphorylationCyclin-Dependent Kinase Inhibitor ProteinsQGenome Integrity & RepairRMedicineCell Cycle & ChromosomesProtein Tyrosine PhosphatasesGenetics & GenomicsStructural Biology & Biophysics

Sustainable Development Goals

SDG 3: 3. Good health

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (8)

Funding (22 grants)

Open Access

Topics

Annotations (Europe PMC)