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Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection

(2023)10.7554/elife.86931.1Source: DataRank Database

Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection is a research paper (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: goldTopics (34)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Belinda S. Hall ORCID,Jane Newcombe,Tom A. Mendum ORCID,Yagnesh Umrania ORCID,Michael J. Deery ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4376611929

Wellcome Trust

Grant: WT202843/Z/16/Z

National Institute of General Medical Sciences

Grant: GM116032

Medical Research Council

Grant: MR/W02618X/1

Wellcome Trust

Grant: 202843

Investigating the role of coagulation in the pathogenesis of Buruli ulcer

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.86931.1

publisherhttps://doi.org/10.7554/elife.86931.1

publisherhttps://cdn.elifesciences.org/preprints/86931/elife-preprint-86931-v1.pdf

publisherhttps://cdn.elifesciences.org/preprints/86931/elife-preprint-86931-v1.xml

publisherhttps://elifesciences.org/reviewed-preprints/86931v1/pdf

Fields of Study

Mycobacterium research and diagnosisFungal Biology and ApplicationsPharmacological Effects of Natural Compounds0301 basic medicine03 medical and health sciences

Keywords

Cell biologyBasement membranePerlecanExotoxinBiologyGlycocalyxExtracellular matrixHeparan sulfateBiochemistryGlycosaminoglycanProteoglycanProteomicsWound HealingMycobacterium ulceransCytotoxicityEndothelial cellsCell adhesionExotoxinsPermeabilityArticleNecrosisMicrovasculatureGolgi apparatusMembrane proteinsBasement membranesProteoglycansLamininBuruli ulcerGlycosaminoglycans

Sustainable Development Goals

SDG 3: 3. Good health