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CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment

eLife(2023)10.7554/elife.87281.3Source: DataRank Database

CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment is a research paper published in eLife (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 0.15)OA: goldTopics (45)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Xuexiang Du ORCID,Mingyue Liu ORCID,Xu Wang ORCID,Wei Wu ORCID,Chunxia Ai

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4390061788

National Institutes of Health

Grant: R01AI154722

National Institutes of Health

Grant: 5R01AI154722-03

Preserving CTLA-4 immune checkpoint for safer and more effective cancer immunotherapy

FWCI

0.15

Citation Percentile

0.6%

Citation Trend

2023

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.87281.3

publisherhttps://doi.org/10.7554/elife.87281.3

publisherhttps://cdn.elifesciences.org/articles/87281/elife-87281-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/87281/elife-87281-v1.xml

publisherhttps://elifesciences.org/articles/87281

Fields of Study

T-cell and B-cell ImmunologyCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction03 medical and health sciences0302 clinical medicine

Keywords

CTLA-4ImmunologyCytotoxic T cellFOXP3AntibodyCD8B cellRegulatory B cellsImmune systemIpilimumabT cellBiologyCancer researchMedicineImmunotherapyIn vitroMaleQH301-705.5ScienceImmunoglobulinsTreg-depletionApoptosisCHO CellsT-Lymphocytes, RegulatoryArticleLymphocyte DepletionB cell lossAbataceptMiceImmunology and InflammationCricetulusAnimalsCTLA-4 AntigenBiology (General)B-LymphocytesQRMice, Inbred C57BLADCFemale

Sustainable Development Goals

SDG 0: Good health and well-being