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Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury

eLife(2023)10.7554/elife.87528Source: DataRank Database

Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury is a research paper published in eLife (2023). On theSindex it has a DataRank of 0.118. It has been cited 1 time, with 1 citing works in its 1-hop citation network.

N/A

0.118DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access1 citations · 1 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE223321 GSE184547 GSE190667 GSE168789 GSE137400

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: goldTopics (29)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 88%Citation Network 12%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

0.0137

From 1 citing papers with measurable signal

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Top 1 citer driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 1 citer.

ATF2 phosphorylation is a core transcriptional driver of neuron apoptosis
bioRxiv (Cold Spring Harbor Laboratory)20232 citations68 referencesContributes 0.016

Authors (12)

Madeline M. Farley ORCID,Melissa A. Rudy ORCID,Katya Sigal ORCID,Andoni I Asencor ORCID,David G. Stefanoff

Live enrichment

PubMed:41744494 PMC:PMC12945389 OpenAlex:https://openalex.org/W4377983719

National Institutes of Health

Grant: R01NS112691

National Institutes of Health

Grant: R01NS076708

National Institutes of Health

Grant: R00EY029360

NEI NIH HHS

Grant: R01 EY036111

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.87528

publisherhttps://doi.org/10.7554/elife.87528

publisherhttps://cdn.elifesciences.org/articles/87528/elife-87528-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/87528/elife-87528-v1.xml

publisherhttps://elifesciences.org/articles/87528

Fields of Study

Nerve injury and regenerationCell death mechanisms and regulationRetinal Development and Disorders

Keywords

ATF4NeuroprotectionNeuroscienceAxonNeurodegenerationCell biologyKnockout mouseBiologyTranscription factorConditional gene knockoutIntegrated stress responseRegeneration (biology)PTENCancer researchUnfolded protein responseSignal transductionMedicinePI3K/AKT/mTOR pathwayGeneticsPathologyGeneTranslation (biology)Endoplasmic reticulumMouseRetinal ganglion cellAxon regeneration

Sustainable Development Goals

SDG 0: Good health and well-being