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Water and chloride as allosteric inhibitors in WNK kinase osmosensing

eLife(2023)10.7554/elife.88224Source: DataRank Database

Water and chloride as allosteric inhibitors in WNK kinase osmosensing is a research paper published in eLife (2023). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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Enrichment:Funding (10 grants)OA: goldTopics (61)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

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Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Radha Akella ORCID,John M. Humphreys ORCID,Haixia He ORCID,Elizabeth J. Goldsmith ORCID,Liliana R. Teixeira ORCID

Live enrichment

PubMed:39584807 PMC:PMC11588334 OpenAlex:https://openalex.org/W4387869110

Mary Kay Ash Foundation

Grant: Liliana R Teixeira

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK110358

Welch Foundation

Grant: I1128

Welch Foundation

Grant: I-2100-20220331

Cancer Prevention and Research Institute of Texas

Grant: RP190421

NIGMS NIH HHS

Grant: P41 GM103393

NIDDK NIH HHS

Grant: R01 DK110358

National Institutes of Health

Grant: 8P41GM103393-33

A Synchroton Radiation Structural Biology Resource

National Institutes of Health

Grant: 2R01DK110358-07A1

Regulation of WNK signaling by potassium and Mo25: structure, function and physiology

Endowment from Patti Bell Brown

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.88224

publisherhttps://doi.org/10.7554/elife.88224

publisherhttps://cdn.elifesciences.org/articles/88224/elife-88224-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/88224/elife-88224-v1.xml

publisherhttps://elifesciences.org/articles/88224

Fields of Study

Ion Transport and Channel RegulationMetabolism, Diabetes, and CancerMagnesium in Health and Disease0301 basic medicine03 medical and health sciencesWaterProtein Serine-Threonine KinasesChloridesPhosphorylationWNK Lysine-Deficient Protein Kinase 1HumansAllosteric RegulationCrystallography, X-RayOsmoregulation

MeSH Terms

WNK Lysine-Deficient Protein Kinase 1Allosteric RegulationChloridesHumansPhosphorylationWaterProtein Serine-Threonine KinasesCrystallography, X-RayOsmoregulation

Keywords

AutophosphorylationAllosteric regulationProtein kinase domainChemistryMutantChloride channelKinaseBiochemistryChlorideBiophysicsCell biologyProtein kinase ABiologyEnzymeGeneWaterE. coliCrystallographyStructural BiologyWnk1Wnk3OsmosensorChloride IonMolecular BiophysicsQH301-705.5ScienceStructural Biology and Molecular BiophysicsQRProtein Serine-Threonine KinasesCrystallography, X-RayOsmoregulationChloridesWNK Lysine-Deficient Protein Kinase 1MedicineHumansBiology (General)Phosphorylation

Sustainable Development Goals

SDG 0: Quality Education

Water and chloride as allosteric inhibitors in WNK kinase osmosensing

FAIR Checklist

Authors (5)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)