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Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease

(2023)10.7554/elife.89782.1Source: DataRank Database

Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease is a research paper (2023). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: goldTopics (25)IDs (PubMed)

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Authors (10)

Jun Wan Shin,Sophia Zeng,Eun Pyo Hong ORCID,Jae-Hyun Jang,Jacob M. Loupe ORCID

Live enrichment

PubMed:21097893

National Institute of Neurological Disorders and Stroke

Grant: NS105709

National Institute of Neurological Disorders and Stroke

Grant: NS119471

National Institute of Neurological Disorders and Stroke

Grant: NS049206

National Institutes of Health

Grant: 5R01NS119471-02

Therapeutic potential of base editing strategies to convert CAG to CAA in Huntington's Disease

National Institutes of Health

Grant: 5R01NS105709-02

Genetic foundation for complete mutant allele-specific CRISPR in neurodegenerative diseases

goldLicense: cc-by

publisherhttps://doi.org/10.7554/elife.89782.1

publisherhttps://cdn.elifesciences.org/preprints/89782/elife-preprint-89782-v1.pdf

publisherhttps://cdn.elifesciences.org/preprints/89782/elife-preprint-89782-v1.xml

publisherhttps://elifesciences.org/reviewed-preprints/89782v1/pdf

https://doi.org/10.7554/elife.89782.2

Fields of Study

0303 health sciences03 medical and health sciences

Keywords

Gene EditingHuntingtin Proteinbase editingQH301-705.5ScienceQCAG-to-CAA conversionRHuntington's diseaseGenetics and Genomicsuninterrupted repeatduplicated interruptionMiceDisease Models, AnimalHuntington DiseaseMutationCAG repeat instabilityMedicineAnimalsHumansGene Knock-In TechniquesBiology (General)Trinucleotide Repeat Expansion