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ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

eLife(2023)10.7554/elife.91930Source: DataRank Database

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages is a research paper published in eLife (2023). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Enrichment:Funding (12 grants)OA: goldTopics (38)IDs (PubMed, PMC)Annotations (1)

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Authors (16)

Mila Trank-Greene ORCID,Xammy Nguyenla ORCID,Aidan Anastas ORCID,Sintayehu K Gurmessa ORCID,Ilaria R Merutka ORCID

Live enrichment

PubMed:38805257 PMC:PMC11132683

Bill and Melinda Gates Foundation

Grant: OPP1179922

National Institutes of Health

Grant: R01AI141549

National Heart, Lung, and Blood Institute

Grant: 5T32HL083808

Canadian Institutes of Health Research

Grant: 168998

Michael Smith Health Research BC

Grant: 17686

OHSU Biophysics Shared Resources Core and equipment

Grant: S10OD023413

NHLBI NIH HHS

Grant: T32 HL083808

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1S10OD023413-01

Octet Red384

National Institutes of Health

Grant: 1R01AI141549-01A1

Determining the role of sphingolipids in Mycobacterium tuberculosis infection

National Institutes of Health

Grant: 1T32HL083808-01A2

Multidisciplinary Research Training in Pulmonary Medicine

Silver Family Foundation

goldLicense: cc-by

publisherhttps://github.com/elifesciences/enhanced-preprints-data/raw/master/data/91930/v1/91930-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/91930/elife-91930-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/91930/elife-91930-v1.xml

publisherhttps://elifesciences.org/articles/91930

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11132683/pdf/elife-91930.pdf

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

PhagosomesMacrophagesHumansMycobacterium tuberculosisBacterial ProteinsAntigens, BacterialHydrogen-Ion ConcentrationMolecular Dynamics SimulationSingle-Domain Antibodies

Keywords

HumanBiochemistryMicrobiologyInfectious diseaseESAT-6NanobodyM. TuberculosisChemical BiologyCfp-10VhhAntigens, BacterialQH301-705.5ScienceMacrophagesQRMycobacterium tuberculosisHydrogen-Ion ConcentrationMolecular Dynamics SimulationSingle-Domain AntibodiesArticleBacterial ProteinsBiochemistry and Chemical BiologyPhagosomesMedicineHumansBiology (General)

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

FAIR Checklist

Authors (16)

Funding (12 grants)

Open Access

Topics

Annotations (Europe PMC)