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Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis

eLife(2023)10.7554/elife.93283Source: DataRank Database

Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis is a research paper published in eLife (2023). On theSindex it has a DataRank of 0.718. It has been cited 23 times, with 20 citing works in its 1-hop citation network.

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0.718DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access23 citations · 20 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE211584 GSE134420 GSE200843 GSE184609 GSE271903

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)OA: goldTopics (48)IDs (PubMed, PMC)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 66%Citation Network 34%

Base Score Contribution

0.477

From this paper's citation signal

Citation Network Contribution

0.242

From 15 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 20 citers.

Monocyte‐Derived Macrophages‐Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis
Arthritis & Rheumatology20258 citations47 referencesContributes 0.047
Integrated proteomic and metabolomic analysis reveals the potential therapeutic mechanism of Quanduzhong capsule in rats with spontaneous hypertension and knee osteoarthritis
Journal of Ethnopharmacology20245 citations56 referencesContributes 0.032
Unveiling the macrophage dynamics in osteoarthritic joints: From inflammation to therapeutic strategies
Drug Discovery Today202421 citations114 referencesContributes 0.027
Network toxicology and machine learning reveal the toxicological impact of Bisphenol A exposure on osteoarthritis
Medicine20252 citations41 referencesContributes 0.027
Delta-9-Tetrahydrocannabinol Blocks Bone Marrow-Derived Macrophage Differentiation through Elimination of Reactive Oxygen Species
Antioxidants20244 citations64 referencesContributes 0.025

Authors (6)

Easton C. Farrell ORCID,Olivia M. Ellis,Michelle J. Song,C. Thomas Appleton ORCID,Tristan Maerz ORCID

Live enrichment

PubMed:39969512 PMC:PMC11839164

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: R21AR076487

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: K99AR081894

Ralph and Marian Falk Medical Research Trust

Grant: Catalyst Award

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: R01AR080035

National Institutes of Health

Grant: R21AR080502

National Institutes of Health

Grant: R21AR082016

Congressionally Directed Medical Research Programs

Grant: HT94252310327

NIAMS NIH HHS

Grant: R00 AR081894

NIAMS NIH HHS

Grant: UC2 AR082186

National Institutes of Health

Grant: 5R21AR080502-02

Bioerodible corticosteroid microparticle-drug as an intra-articular drug delivery system for osteoarthritis therapy

National Institutes of Health

Grant: 3UC2AR082186-01S1

Mapping the joint-nerve interactome of the knee

National Institutes of Health

Grant: 5R01AR080035-03

Sustained Biomaterial-mediated Inhibition of R-spondin 2 to Target Pathological Wnt Signaling in Post-Traumatic Osteoarthritis

National Institutes of Health

Grant: 1K99AR081894-01

Fibrosis, inflammation, and osteophyte formation in post-traumatic osteoarthritis

National Institutes of Health

Grant: 5R21AR082016-02

Autonomous RUNX2 suppression in genetically modified stem cell-derived chondrocytes as a disease modifying therapeutic for PTOA

National Institutes of Health

Grant: 1R21AR076487-01A1

Targeting Pathological Angiogenesis after Joint Injury

goldLicense: cc-by

publisherhttps://doi.org/10.7554/elife.93283

publisherhttps://cdn.elifesciences.org/articles/93283/elife-93283-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/93283/elife-93283-v1.xml

publisherhttps://elifesciences.org/articles/93283

repositoryhttp://hdl.handle.net/20.500.11850/783431

Fields of Study

03 medical and health sciences0302 clinical medicineAnimalsMacrophagesMiceOsteoarthritisSynovial MembraneSignal TransductionMacrophage Colony-Stimulating FactorDisease Models, AnimalMice, Inbred C57BLMale

MeSH Terms

Synovial MembraneMacrophagesAnimalsMice, Inbred C57BLMiceOsteoarthritisDisease Models, AnimalMacrophage Colony-Stimulating FactorSignal TransductionMale

Keywords

MacrophagesMouseInflammationOsteoarthritisimmunologySynoviumJoint InjurySingle-cell Rna-seqMaleSingle-cell RNA-sequencingQH301-705.5ScienceArticleMiceImmunology and InflammationAnimalsBiology (General)Macrophage Colony-Stimulating FactorQSynovial MembraneImmune cellsRMice, Inbred C57BLDisease Models, AnimalMedicineSignal Transduction

Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (6)

Funding (15 grants)

Open Access

Topics

Annotations (Europe PMC)