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Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer

eLife(2024)10.7554/elife.96992Source: DataRank Database

Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer is a research paper published in eLife (2024). On theSindex it has a DataRank of 0. It has been cited 13 times.

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Scored on demand from live citation data

Open Access13 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)OA: goldTopics (69)IDs (PubMed, PMC)Annotations (2)SDGs (1)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Kayla O’Toole ORCID,Sanjana Srinivas Boggaram,Michael T. Scherzer ORCID,Mark R. Silvis ORCID,Yun Zhang ORCID

Live enrichment

PubMed:39213022 PMC:PMC11364435

NCI NIH HHS

Grant: P30 CA042014

NCI NIH HHS

Grant: R01CA131261

National Cancer Institute

Grant: R01CA240317

NCI NIH HHS

Grant: F31CA261116

NCI NIH HHS

Grant: K08 CA230151

National Cancer Institute

Grant: R01CA176839

NCI NIH HHS

Grant: R01CA212415

National Cancer Institute

Grant: R01CA237404

NCI NIH HHS

Grant: R01 CA082577

NCI NIH HHS

Grant: R01CA82577

NCI NIH HHS

Grant: T32 CA265782

NCATS NIH HHS

Grant: UM1 TR004409

National Institutes of Health

Grant: 1R01CA082577-01

P53 MISSENSE MUTATIONS ON TUMORIGENESIS AND VIVO

National Institutes of Health

Grant: 5F31CA261116-02

Investigating KRAS Signaling and Autophagy Co-inhibition in KRAS-mutant Lung Cancer

National Institutes of Health

Grant: 5R01CA212415-04

Transcriptional Regulation of Lung Cancer Identity

National Institutes of Health

Grant: 3R01CA131261-11S1

Studying the initiation, progression and therapy of lung cancer in mouse models

National Institutes of Health

Grant: 5R01CA240317-04

Patho-Genetic Analysis of Invasive Mucinous Adenocarcinoma of the Lung

National Institutes of Health

Grant: 5R01CA176839-02

Targeting Oncogenic BRAF And PI3'-Kinase Signaling For Melanoma Therapy

National Institutes of Health

Grant: 3P30CA042014-30S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5K08CA230151-03

Resistance Mechanisms to Combined Trametinib and 4-aminoquinolones in the Inhibition of Pancreatic Cancer

National Institutes of Health

Grant: 5R01CA237404-04

Lineage specifiers governing pancreatic cancer growth and molecular subtype

Huntsman Cancer Foundation

V Foundation for Cancer Research

Huntsman Cancer Institute, University of Utah

goldLicense: cc-by

publisherhttps://elifesciences.org/reviewed-preprints/96992.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11364435/pdf/elife-96992.pdf

repositoryhttps://doaj.org/article/95323d71411b4fb5a507d99214305120

Europe_PMChttps://europepmc.org/articles/PMC11364435

Europe_PMChttps://europepmc.org/articles/PMC11364435?pdf=render

Fields of Study

0302 clinical medicine03 medical and health sciences

MeSH Terms

Cell Line, TumorAnimalsHumansMiceCarcinoma, Non-Small-Cell LungLung NeoplasmsDisease Models, AnimalPiperazinesPyridinesPyrimidinesIntracellular Signaling Peptides and ProteinsAntineoplastic AgentsCell ProliferationAutophagyFemaleMaleProto-Oncogene Proteins p21(ras)Autophagy-Related Protein-1 HomologProtein Serine-Threonine Kinases

Keywords

MouseLung cancerAutophagyKrasCancer BiologyTp53Lkb1UlkMaleMedical SciencesLung NeoplasmsPulmonologyPyridinesRespiratory Tract DiseasesDiseasesPiperazinesMiceCarcinoma, Non-Small-Cell LungMedical SpecialtiesMedicine and Health SciencesAutophagy-Related Protein-1 HomologBiology (General)Non-Small-Cell LungTumorQRIntracellular Signaling Peptides and ProteinsOncologyMedicineFemaleBioinformaticsQH301-705.5Science610Antineoplastic AgentsProtein Serine-Threonine KinasesCell LineBiomedical InformaticsProto-Oncogene Proteins p21(ras)Cell Line, TumorAnimalsHumansCell ProliferationAnimalCarcinomaDisease Models, AnimalPyrimidinesDisease Models

Sustainable Development Goals

SDG 3: 3. Good health