Ralph A. Nixon

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.2Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease

Nature Neuroscience(2022)10.1038/s41593-022-01166-7

Top 17%

1.2DataRank

Top 17%65 citations

Mads E. Hauberg, Kiran Girdhar, Eunju Im, James M. Vicari, Samir Rahman +17 more

Papers

Driven by 25 papers — median percentile 83. Top paper: “A gene toolbox for monitoring autophagy transcription”.

A gene toolbox for monitoring autophagy transcription

Cell Death and Disease(2021)10.1038/s41419-021-04121-9

N/A

3.0DataRank · unranked

147 citations

Rossella De Cegli, Beatrice Testa, Ralph A. Nixon, Andrea Ballabio, Francesco Cecconi +1 more

Autophagy–lysosomal-associated neuronal death in neurodegenerative disease

Acta Neuropathologica(2024)10.1007/s00401-024-02799-7

N/A

1.4DataRank · unranked

89 citations

Ralph A. Nixon

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease

Nature Neuroscience(2022)10.1038/s41593-022-01166-7

Top 17%

1.2DataRank

Top 17%65 citations

Mads E. Hauberg, Kiran Girdhar, Eunju Im, James M. Vicari, Samir Rahman +17 more

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Nature Neuroscience(2022)10.1038/s41593-022-01084-8

N/A

0.965DataRank · unranked

623 citations

Dun‐Sheng Yang, Chris N. Goulbourne, Eunju Im, Philip Stavrides, Anna Pensalfini +12 more

Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology

The American Journal of Pathology(2008)10.2353/ajpath.2008.071053

N/A

0.786DataRank · unranked

188 citations

Paul M. Mathews, Anne Boyer Boiteau, Linda C. Hassinger, Corrinne M. Peterhoff, Ying Jiang +5 more

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

Cell Reports(2021)10.1016/j.celrep.2021.109034

N/A

0.683DataRank · unranked

94 citations

Dun‐Sheng Yang, Philip Stavrides, Chris N. Goulbourne, Ping Chen Jue-Ru Zheng, Panaiyur S. Mohan +3 more

Autophagy is a novel pathway for neurofilament protein degradation in vivo

Autophagy(2022)10.1080/15548627.2022.2124500

N/A

0.510DataRank · unranked

29 citations

Sandipkumar Darji, Philip Stavrides, Chris N. Goulbourne, Asok Kumar, Dun‐Sheng Yang +6 more

A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.22.533675

N/A

0.477DataRank · unranked

23 citations

Suzanne Elsasser, Lisa P. Elia, Richard I. Morimoto, Evan T. Powers, Daniel Finley +23 more

The three-dimensional landscape of chromatin accessibility in Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.426303

N/A

0.396DataRank · unranked

13 citations

Mads E. Hauberg, Kiran Girdhar, Eunju Im, James M. Vicari, Samir Rahman +14 more

Lysosomal dysfunction in Down Syndrome and Alzheimer mouse models is caused by selective v-ATPase inhibition by Tyr 682 phosphorylated APP βCTF

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.02.494546

N/A

0.292DataRank · unranked

6 citations

Ying Jiang, Philip Stavrides, Sandipkumar Darji, Hediye Erdjument‐Bromage, Thomas A. Neubert +5 more

Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer’s Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration

Journal of Neuroscience(2025)10.1523/jneurosci.2331-24.2025

N/A

0.104DataRank · unranked

1 citations

Kuldeep Singh Sachdeva, Chris N. Goulbourne, Martin J. Berg, James Peddy, Philip Stavrides +11 more

Posttranscriptional regulation of neurofilament proteins and tau in health and disease

Brain Research Bulletin(2022)10.1016/j.brainresbull.2022.10.017

N/A

0DataRank · unranked

15 citations

Ralph A. Nixon, Aidong Yuan

The aging lysosome: An essential catalyst for late-onset neurodegenerative diseases

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics(2020)10.1016/j.bbapap.2020.140443

N/A

0DataRank · unranked

154 citations

Ralph A. Nixon

Disease-modifying pharmacological approaches to correcting basal forebrain cholinergic neuronal (BFCN) dysfunction and degeneration

Neuropsychopharmacology(2021)10.1038/s41386-021-01135-x

N/A

0DataRank · unranked

2 citations

Ralph A. Nixon, John Alam

Correction: Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come

Molecular Neurodegeneration(2023)10.1186/s13024-023-00678-5

N/A

0DataRank · unranked

0 citations

Ralph A. Nixon, John Alam

β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.02.021

N/A

0DataRank · unranked

37 citations

Devin M. Wolfe, Sandipkumar Darji, Mary Kate McBrayer, Daniel J. Colacurcio, Asok Kumar +4 more

Increased neuronal expression of the early endosomal adaptor APPL1 replicates Alzheimer’s Disease-related endosomal and synaptic dysfunction with cholinergic neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.19.613736

N/A

0DataRank · unranked

0 citations

Kuldeep Singh Sachdeva, Chris N. Goulbourne, Martin J. Berg, James Peddy, Philip Stavrides +11 more

Pathophysiologic abnormalities in transgenic mice carrying the Alzheimer disease PSEN1 Δ440 mutation

Human Molecular Genetics(2024)10.1093/hmg/ddae139

N/A

0DataRank · unranked

0 citations

Victoria L Collis, Pallavi Sharma, Angelina M Burkett, Shaoteng Wang, Kyle A. Brown +7 more

mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

eLife(2025)10.7554/elife.104979.3

N/A

0DataRank · unranked

3 citations

Chris N. Goulbourne, James Peddy, Chunfeng Huo, Mala V. Rao, Vinod Khetarpal +4 more

Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling

Journal of Neuroscience Methods(2025)10.1016/j.jneumeth.2025.110512

N/A

0DataRank · unranked

1 citations

Kyrillos W. Ibrahim, Philip Stavrides, J Christopher Bare, Melissa J. Alldred, Adriana Heguy +3 more

Pathobiology of the autophagy-lysosomal pathway in the Huntington’s disease brain

Acta Neuropathologica Communications(2025)10.1186/s40478-025-02131-8

N/A

0DataRank · unranked

1 citations

Veeranna, Corrinne M. Rosa, Asok Kumar, Panaiyur S. Mohan, Philip Stavrides +5 more

Calpastatin, a calpain specific inhibitor, reduce seizures in a mouse model of temporal lobe epilepsy

Epilepsia Open(2025)10.1002/epi4.70030

N/A

0DataRank · unranked

1 citations

Mala V. Rao, Ralph A. Nixon, Marco I. González, Philip M. Lam

mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

eLife(2025)10.7554/elife.104979

N/A

0DataRank · unranked

1 citations

Chris N. Goulbourne, James Peddy, Chunfeng Huo, Mala Rao, Vinod Khetarpal +4 more

Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis

Autophagy(2022)10.1080/15548627.2022.2110729

N/A

0DataRank · unranked

32 citations

Ralph A. Nixon, Ju‐Hyun Lee

Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease

Cell Reports(2020)10.1016/j.celrep.2020.108420

N/A

0DataRank · unranked

130 citations

Seonil Kim, Shivakumar Subbanna, Cynthia Bleiwas, Chris N. Goulbourne, Philip Stavrides +11 more

Ralph A. Nixon

Indexed papers

Top data-sharing exemplar

Papers