William C. Groutas

Biochemistry, Genetics and Molecular BiologyMedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 12 papers. Top paper: “Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies”.

Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00206

N/A

0.396DataRank · unranked

13 citations

Harry Nhat Nguyen, Athri D. Rathnayake, Yunjeong Kim, Krishani Dinali Perera, Trent K. Madden +9 more

Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01252

N/A

0DataRank · unranked

18 citations

Yunjeong Kim, Chamandi S. Dampalla, Harry Nhat Nguyen, Abdul-Rahman M. Jesri, M.M. Kashipathy +6 more

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2101555118

N/A

0DataRank · unranked

79 citations

Jian Zheng, Krishani Dinali Perera, Lok-Yin Roy Wong, David K. Meyerholz, Harry Nhat Nguyen +8 more

Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.05.429937

N/A

0DataRank · unranked

19 citations

Jian Zhang, Krishani Dinali Perera, Lok-Yin Roy Wong, David K. Meyerholz, Harry Nhat Nguyen +8 more

Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.

ChemRxiv(2021)10.26434/chemrxiv.14781567.v1

N/A

0DataRank · unranked

2 citations

Athri D. Rathnayake, Krishani Dinali Perera, Abdul-Rahman M. Jesri, Harry Nhat Nguyen, Matthew J. Miller +10 more

Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.

ChemRxiv(2021)10.26434/chemrxiv.14781567

N/A

0DataRank · unranked

1 citations

Athri D. Rathnayake, Krishani Dinali Perera, Abdul-Rahman M. Jesri, Harry Nhat Nguyen, Matthew J. Miller +10 more

Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus

Microbiology Spectrum(2022)10.1128/spectrum.00142-22

N/A

0DataRank · unranked

3 citations

David K. Johnson, Scott Lovell, William C. Groutas, Kyeong‐Ok Chang, Yunjeong Kim +1 more

Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV)

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115376

N/A

0DataRank · unranked

15 citations

Matthew J. Miller, Yunjeong Kim, Alexandria Zabiegala, Harry Nhat Nguyen, Trent K. Madden +9 more

Potent 3CLpro inhibitors effective against SARS-CoV-2 and MERS-CoV in animal models by therapeutic treatment

mBio(2023)10.1128/mbio.02878-23

N/A

0DataRank · unranked

5 citations

Yunjeong Kim, Chamandi S. Dampalla, Harry Nhat Nguyen, David K. Meyerholz, David K. Johnson +5 more

Potent small molecule inhibitors against the 3C protease of foot-and-mouth disease virus

Microbiology Spectrum(2024)10.1128/spectrum.03372-23

N/A

0DataRank · unranked

4 citations

Emma Pool, Eunji Kim, Chamandi S. Dampalla, Harry Nhat Nguyen, David K. Johnson +4 more

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice

Science Translational Medicine(2020)10.1126/scitranslmed.abc5332

N/A

0DataRank · unranked

295 citations

Jian Zheng, Yunjeong Kim, Krishani Dinali Perera, Samantha Mackin, David K. Meyerholz +7 more

Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00551

N/A

0DataRank · unranked

2 citations

Yunjeong Kim, Alexandria Zabiegala, Dennis J. Howard, Harry Nhat Nguyen, Trent K. Madden +8 more