John P. O’Bryan

Also affiliated with MUSC Hollings Cancer Center, Ralph H. Johnson VA Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Targeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis”.

Targeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis

Small GTPases(2021)10.1080/21541248.2021.1906621

N/A

0.631DataRank · unranked

16 citations

Catherine Marelia-Bennet, Julia E. Lefler, Mariyam Zuberi, Eric Denbaum, Akiko Koide +8 more

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer

Cell Death and Differentiation(2024)10.1038/s41418-024-01310-9

N/A

0.587DataRank · unranked

49 citations

Colleen E. Quaas, Irene Bertolini, Alessandro Zuccotti, Özge Saatci, Jennifer A. Kashatus +14 more

Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2302485120

N/A

0.533DataRank · unranked

34 citations

Takamitsu Hattori, Imran Mahmood Khan, Eliezra Glasser, Akiko Koide, Gayatri Ketavarapu +10 more

Targeting the “undruggable” RAS with biologics

Advances in cancer research(2022)10.1016/bs.acr.2021.07.006

N/A

0.477DataRank · unranked

23 citations

Imran Khan, John P. O’Bryan, Michael Whaby

The Src Homology 2 and Phosphotyrosine Binding Domains of the ShcC Adaptor Protein Function as Inhibitors of Mitogenic Signaling by the Epidermal Growth Factor Receptor

UNC Libraries(2021)10.17615/hsnq-cv96

N/A

0DataRank · unranked

0 citations

John P. O’Bryan, Channing J. Der, Que T. Lambert

Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204481119

N/A

0DataRank · unranked

24 citations

Imran Khan, Kai Wen Teng, Akiko Koide, Mariyam Zuberi, Jianping Li +5 more

Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway

Leukemia(2022)10.1038/s41375-022-01581-6

N/A

0DataRank · unranked

21 citations

Linlu Tian, Steven Schutt, Imran Mahmood Khan, Hee-Jin Choi, Yongxia Wu +14 more

Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102661

N/A

0DataRank · unranked

15 citations

Lauren Wallon, Megan Mazzei, Imran Khan, Kai Wen Teng, Shohei Koide +2 more

Inhibition and degradation of NRAS with a pan-NRAS monobody

Oncogene(2024)10.1038/s41388-024-03186-y

N/A

0DataRank · unranked

9 citations

Gayatri Ketavarapu, Akiko Koide, Megan Mazzei, Mubashir J. Mintoo, Eliezra Glasser +7 more

Probing RAS Function Using Monobody and NanoBiT Technologies

Methods in molecular biology(2024)10.1007/978-1-0716-3822-4_15

N/A

0DataRank · unranked

1 citations

Rakesh Sathish Nair, John P. O’Bryan, Michael Whaby

A High-Affinity Monoclonal Antibody Against the Pancreatic Ductal Adenocarcinoma Target, Anterior Gradient-2 (AGR2/PDIA17)

Antibodies(2024)10.3390/antib13040101

N/A

0DataRank · unranked

0 citations

Leticia Reyes, Benjamin Christopher, Ravyn M. Duncan, Rachel A. Burge, Julie B. Siegel +7 more

Modulating the CXCR2 Signaling Axis Using Engineered Chemokine Fusion Proteins to Disrupt Myeloid Cell Infiltration in Pancreatic Cancer

Biomolecules(2025)10.3390/biom15050645

N/A

0DataRank · unranked

3 citations

Lena Golick, Ashton Basar, Leticia Reyes, Reeder M. Robinson, Aaron O. Angerstein +6 more

Regulation of Neuron Survival through an Intersectin-Phosphoinositide 3'-Kinase C2 -AKT Pathway

UNC Libraries(2020)10.17615/cwqb-0x09

N/A

0DataRank · unranked

1 citations

Erica Scappini, J. Domin, Y.-J. Chen, S.M. Dunn, John P. O’Bryan +4 more

Pancreatic Cells Are Resistant to KRASQ61L Expression due to Hyperactive ERK/MAPK Signaling and Apoptosis Induction

Cancer Research Communications(2025)10.1158/2767-9764.crc-25-0281

N/A

0DataRank · unranked

0 citations

Lucas Bialousow, Thomas McFall, Logan Bamonte, Grayson Johnson, Merissa Smith +7 more

The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2

Nature Communications(2021)10.1038/s41467-021-23408-1

N/A

0DataRank · unranked

105 citations

Sudhahar Varadarajan, Seock‐Won Youn, Mustafa Nazir Okur, Archita Das, John P. O’Bryan +6 more

Selective and noncovalent targeting of RAS mutants for inhibition and degradation

Nature Communications(2021)10.1038/s41467-021-22969-5

N/A

0DataRank · unranked

86 citations

Steven T. Tsai, Takamitsu Hattori, Carmine Fedele, Akiko Koide, Chao Yang +6 more

Neuroblastoma differentiation in vivo excludes cranial tumors

Developmental Cell(2021)10.1016/j.devcel.2021.09.014

N/A

0DataRank · unranked

6 citations

Sriivatsan G. Rajan, Xinghang Jiang, Lynne M. Nacke, Usama A. Malkana, L.A. Naiche +7 more