Zhong-Yin Zhang

MedicineComputer ScienceChemistryImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Functional interrogation and therapeutic targeting of protein tyrosine phosphatases”.

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Biochemical Society Transactions(2021)10.1042/bst20201308

N/A

0.464DataRank · unranked

21 citations

Zhong-Yin Zhang, Aaron D. Krabill

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation

Molecular Cancer Research(2023)10.1158/1541-7786.mcr-23-0115

N/A

0.269DataRank · unranked

5 citations

Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Sergio Barajas, Wenjie Cai +25 more

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

Angewandte Chemie International Edition(2025)10.1002/anie.202525126

N/A

0.112DataRank · unranked

1 citations

Frederick Nguele Meke, Zheng Zhang, Zhong‐Yin Zhang, Aaron D. Krabill, Christine S. Muli +12 more

Inhibition of PRMT5 by market drugs as a novel cancer therapeutic avenue

Genes & Diseases(2022)10.1016/j.gendis.2022.04.001

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0DataRank · unranked

16 citations

Matthew Martin, Lan Chen, Özlem Demir, Jiamin Jin, Xiumei Huang +13 more

An Integrated Proteomic Strategy to Identify SHP2 Substrates

Journal of Proteome Research(2022)10.1021/acs.jproteome.2c00481

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0DataRank · unranked

16 citations

Xiaofeng Wu, Ruoyu Zhang, Chuan‐Chih Hsu, Zhong-Yin Zhang, W. Andy Tao +1 more

Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01143

N/A

0DataRank · unranked

11 citations

Jifeng Wang, Zhihong Yu, Julie S. Moyers, M. Dodson Michael, Timothy B. Durham +8 more

Nano-DESI Mass Spectrometry Imaging of Proteoforms in Biological Tissues with High Spatial Resolution

Analytical Chemistry(2023)10.1021/acs.analchem.2c04795

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0DataRank · unranked

90 citations

Daisy Unsihuay, Hang Hu, Frederick Nguele Meke, Zihan Qu, Zhong-Yin Zhang +2 more

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

Nature Communications(2023)10.1038/s41467-023-40170-8

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0DataRank · unranked

84 citations

Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen +9 more

Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy

Angewandte Chemie International Edition(2023)10.1002/anie.202303818

N/A

0DataRank · unranked

56 citations

Jinmin Miao, Yiming Miao, Zihan Qu, Sheng Zhang, Peipei Zhu +10 more

Discovery of a selective TC-PTP degrader for cancer immunotherapy

Chemical Science(2023)10.1039/d3sc04541b

N/A

0DataRank · unranked

17 citations

Jiajun Dong, Yiming Miao, Yunpeng Bai, Zihan Qu, Brenson A. Jassim +8 more

Inhibition of PRL2 Upregulates PTEN and Attenuates Tumor Growth in Tp53 -deficient Sarcoma and Lymphoma Mouse Models

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0308

N/A

0DataRank · unranked

5 citations

Yunpeng Bai, Diego Ruiz-Avila, Colin Carlock, Jinan Ayub, Jinmin Miao +4 more

Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy

Angewandte Chemie(2023)10.1002/ange.202303818

N/A

0DataRank · unranked

1 citations

Jinmin Miao, Yiming Miao, Zihan Qu, Sheng Zhang, Peipei Zhu +10 more

The protein tyrosine phosphatase Lyp/PTPN22 drives TNFα-induced priming of superoxide anions production by neutrophils and arthritis

Free Radical Biology and Medicine(2024)10.1016/j.freeradbiomed.2024.12.046

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0DataRank · unranked

7 citations

Viviana Marzaioli, Samia Bedouhène, Gilles Hayem, Margarita Hurtado-Nédelec, Yantao He +6 more

Drugging Protein Tyrosine Phosphatases through Targeted Protein Degradation

ChemMedChem(2024)10.1002/cmdc.202300669

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0DataRank · unranked

6 citations

Zhong-Yin Zhang, Jinmin Miao

Targeting PRL phosphatases in hematological malignancies

Expert Opinion on Therapeutic Targets(2024)10.1080/14728222.2024.2344695

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0DataRank · unranked

4 citations

Hongxia Chen, Yunpeng Bai, Zhong-Yin Zhang, Yan Liu, Shiyu Xiao

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor

Biochemical Journal(2024)10.1042/bcj20240626

N/A

0DataRank · unranked

4 citations

Yunpeng Bai, Sarah M. Cavender, Yiming Miao, Frederick Nguele Meke, Emily L. Lasse-Opsahl +5 more

Structure-activity relationship studies and design of a PTPN22 inhibitor with enhanced isozyme selectivity and cellular efficacy

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.117129

N/A

0DataRank · unranked

2 citations

Yunpeng Bai, Zihan Qu, C. Sander, Jianping Lin, Jinmin Miao +2 more

Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00149

N/A

0DataRank · unranked

4 citations

Brenson A. Jassim, Kedric L. Milholland, Zihan Qu, Yunpeng Bai, Yiming Miao +6 more

Covalent-Allosteric Inhibitors: Do We Get the Best of Both Worlds?

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02760

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0DataRank · unranked

20 citations

Bo Yang, Atena Farhangian, Ke Xu, Tongtong Li, Zhong-Yin Zhang +2 more

Taking the 3Rs to a higher level: replacement and reduction of animal testing in life sciences in space research

Biotechnology Advances(2025)10.1016/j.biotechadv.2025.108574

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0DataRank · unranked

6 citations

Daniela Grimm, Sarah Baatout, Bjorn Baselet, Afshin Beheshti, Markus Braun +28 more

Illuminating the Druggable Human Proteome with an AI Protein Profiling Platform

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.07.670677

N/A

0DataRank · unranked

0 citations

Daniel Kortzak, Ruibin Liu, Mingzhe Shen, Zhong-Yin Zhang, Zhong‐Yin Zhang +1 more

Illuminating the Druggable Proteome with an AI Protein Profiling Platform

Research Square(2025)10.21203/rs.3.rs-7667948/v1

N/A

0DataRank · unranked

0 citations

Guy W. Dayhoff, Daniel Kortzak, Ruibin Liu, Mingzhe Shen, Zhong-Yin Zhang +1 more

Therapeutic Targeting of Protein Tyrosine Phosphatases from Mycobacterium tuberculosis

Microorganisms(2020)10.3390/microorganisms9010014

N/A

0DataRank · unranked

28 citations

Devesh Aggarwal, Zhong-Yin Zhang, Kasi Viswanatharaju Ruddraraju

Synergistic effects of deleting the tyrosine phosphatases Shp1 and Shp2 on megakaryopoiesis and thrombopoiesis in mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.24.684367

N/A

0DataRank · unranked

0 citations

Marc‐Damien Lourenco‐Rodrigues, Luc J. I. Zimmermann, Marion Pugliano, Cécile Loubière, Fabienne Proamer +8 more

The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors

Nature Communications(2021)10.1038/s41467-021-26526-y

N/A

0DataRank · unranked

46 citations

Yoshihito Kano, Jonathan St‐Germain, Nikolina Radulovich, Molly L. Udaskin, Ahmet Mentes +17 more

PTPN22: structure, function, and developments in inhibitor discovery with applications for immunotherapy

Expert Opinion on Drug Discovery(2022)10.1080/17460441.2022.2084607

N/A

0DataRank · unranked

25 citations

Jianping Lin, Zhong-Yin Zhang, Brenson A. Jassim