Robert A. Casero

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy”.

Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.012376

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78 citations

Jackson R. Foley, Tracy Murray Stewart, John M. Asara, Robert A. Casero, Alex Toker +1 more

Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex

Human Molecular Genetics(2020)10.1093/hmg/ddaa121

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9 citations

James T Mckenna, Caroline Yoon, Tracy Murray Stewart, Robert A. Casero, Michael J. Gambello +1 more

Identification of a novel substrate-derived spermine oxidase inhibitor

Acta Naturae(2020)10.32607/actanaturae.10992

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9 citations

М. А. Хомутов, Sandra B. Gabelli, Tracy Murray Stewart, Jackson R. Foley, Sergey N. Kochetkov +3 more

Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.08.899492

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5 citations

Jackson R. Foley, Tracy Murray Stewart, John M. Asara, Robert A. Casero, Alex Toker +1 more

A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics

Bioorganic Chemistry(2021)10.1016/j.bioorg.2021.105297

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19 citations

Radhika Koranne, Samkeliso Dlamini, Abdulateef Alqahtani, Endri Karaj, Maisha S. Rashid +8 more

Hyperglycemic Conditions Proliferate Triple Negative Breast Cancer Cells: Role of Ornithine Decarboxylase

Research Square(2021)10.21203/rs.3.rs-520490/v1

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3 citations

Caleb Capellen, Jose A. Ortega, M. Jane Morwitzer, Hadassha M. N. Tofilau, Matthew Dunworth +2 more

Expanded Potential of the Polyamine Analogue SBP-101 (Diethyl Dihydroxyhomospermine) as a Modulator of Polyamine Metabolism and Cancer Therapeutic

International Journal of Molecular Sciences(2022)10.3390/ijms23126798

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21 citations

Jackson R. Foley, Tracy Murray Stewart, Robert A. Casero, Cassandra E. Holbert

Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102407

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20 citations

Jackson R. Foley, Cassandra E. Holbert, Glynis Klinke, Gernot Poschet, Raphael R. Steimbach +3 more

Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells

JCI Insight(2022)10.1172/jci.insight.158457

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17 citations

Yi Zhu, Zoraida Diaz-Perez, Seok‐Ho Yu, Jackson R. Foley, Tracy Murray Stewart +4 more

Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers

Biomaterials Advances(2022)10.1016/j.bioadv.2022.212755

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15 citations

Siyuan Tang, Ling Ding, Jackson R. Foley, Weimin Tang, Huizhen Jia +9 more

Polyamine Depletion Strategies in Cancer: Remodeling the Tumor Immune Microenvironment to Enhance Anti-Tumor Responses

Medical Sciences(2022)10.3390/medsci10020031

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15 citations

Charles J. Bieberich, Tracy Murray Stewart, Robert A. Casero, Alexander L. Chin

Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

Medical Sciences(2022)10.3390/medsci10030044

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10 citations

Jackson R. Foley, Ao Yu, Tracy Murray Stewart, Otto Phanstiel, David Oupický +2 more

Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

Molecules(2022)10.3390/molecules27082441

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2 citations

Sudipta Panja, Chinmay M. Jogdeo, Raj Kumar, Ao Yu, Cassandra E. Holbert +6 more

Elucidating the Role of Chmp1 Overexpression in the Transport of Polyamines in Drosophila melanogaster

Medical Sciences(2022)10.3390/medsci10030045

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3 citations

Robert A. Casero, Otto Phanstiel, Justin R. DiAngelo, Shannon L. Nowotarski, Coryn L. Stump

Renal Transcriptome and Metabolome in Mice with Principal Cell-Specific Ablation of the Tsc1 Gene: Derangements in Pathways Associated with Cell Metabolism, Growth and Acid Secretion

International Journal of Molecular Sciences(2022)10.3390/ijms231810601

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2 citations

Sharon Barone, Marybeth Brooks, Tracy Murray Stewart, Robert A. Casero, Manoocher Soleimani +1 more

Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout

ChemRxiv(2022)10.26434/chemrxiv-2021-37shs-v2

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1 citations

Corey J. Herbst‐Gervasoni, Severin Lechner, Tracy Murray Stewart, Glynis Klinke, Johannes Ridinger +13 more

Diabetic Triple Negative Breast Cancer: Polyamine Enzymes, Ornithine decarboxylase and Spermine oxidase as Potential Targets

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4686

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0 citations

Robert A. Casero, Surabhi Chandra, Hadassha M. N. Tofilau

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome

EMBO Molecular Medicine(2023)10.15252/emmm.202317833

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22 citations

Jackson R. Foley, Cassandra E. Holbert, М. А. Хомутов, Noushin Rastkari, Xianzun Tao +4 more

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis

Human Genetics and Genomics Advances(2023)10.1016/j.xhgg.2023.100206

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12 citations

Mollie R. Shinkle, Spencer R. Rosario, Tracy Murray Stewart, Jackson R. Foley, Robert A. Casero +4 more

Polyamine transport inhibition and cisplatin synergistically enhance tumor control through oxidative stress in murine head and neck cancer models

Oral Oncology Reports(2023)10.1016/j.oor.2023.100123

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1 citations

Nathaniel Wang, Jackson R. Foley, Tracy Murray Stewart, Mark R. Burns, Robert A. Casero +3 more

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.15.524155

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2 citations

Anushe Munir, Marie A. Johnson, Megan S. Perez, Yuan Gao, Jackson R. Foley +6 more

Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.17.533015

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2 citations

Jiaqi Liu, Zoraida Diaz-Perez, Jackson R. Foley, Tracy Murray Stewart, Robert A. Casero +2 more

Data from Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

(2023)10.1158/1078-0432.c.6517362.v1

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0 citations

Tracy Murray Stewart, Yu Wu, Stephen B. Baylin, Laurence J. Marton, Brandy Perkins +4 more

Polyamines: the pivotal amines in influencing the tumor microenvironment

Discover Oncology(2024)10.1007/s12672-024-01034-9

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36 citations

Robert A. Casero, Tracy Murray Stewart, Cassandra E. Holbert

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a mouse model of Snyder–Robinson syndrome

Disease Models & Mechanisms(2024)10.1242/dmm.050639

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19 citations

Anushe Munir, Marie A. Johnson, Megan S. Perez, Yuan Gao, Jackson R. Foley +7 more

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation

Cell Death and Disease(2024)10.1038/s41419-024-06720-8

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12 citations

Jiaqi Liu, Zoraida Diaz-Perez, Jackson R. Foley, Ashley Nwafor, Tracy Murray Stewart +3 more

The Synergistic Benefit of Combination Strategies Targeting Tumor Cell Polyamine Homeostasis

International Journal of Molecular Sciences(2024)10.3390/ijms25158173

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10 citations

Tracy Murray Stewart, Robert A. Casero, T. Y. Alvin Liu

The Polyamine Analogue Ivospemin Increases Chemotherapeutic Efficacy in Murine Ovarian Cancer

Biomedicines(2024)10.3390/biomedicines12061157

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3 citations

Jackson R. Foley, Robert A. Casero, Tracy Murray Stewart, Cassandra E. Holbert

Polyamine Depletion by D, L-alpha-difluoromethylornithine Inhibits Ewing Sarcoma Metastasis by Inducing Ferroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.14.599064

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3 citations

Kyle W. Jackson, Masanori Hayashi, Jinghang Zhang, Da Peng, Yuqi Tan +7 more

Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer

medRxiv(2024)10.1101/2024.12.12.24318845

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3 citations

Sheila Jonnatan, David E. Sanin, Varsha Vakkala, Anoushka Kadam, Shivani Kumar +20 more

Polyamine Depletion by D,L-α-Difluoromethylornithine Inhibits Ewing Sarcoma Metastasis by Inducing Ferroptosis

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-24-1778

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7 citations

Kyle W. Jackson, Masanori Hayashi, Jinghang Zhang, Da Peng, Yuqi Tan +7 more

An enhanced method for the determination of polyamine content in biological samples by dansyl chloride derivatization and HPLC

Methods in enzymology on CD-ROM/Methods in enzymology(2025)10.1016/bs.mie.2025.01.066

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3 citations

Tracy Murray Stewart, Robert A. Casero, Ashley Nwafor