Rǎzvan L. Cornea

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 40 papers. Top paper: “The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor”.

The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor

Redox Biology(2020)10.1016/j.redox.2020.101729

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0DataRank · unranked

15 citations

Elisa Bovo, Robyn T. Rebbeck, Daniel Kahn, David D. Thomas, Rǎzvan L. Cornea +2 more

Resolved Structural States of Calmodulin in Regulation of Skeletal Muscle Calcium Release

Biophysical Journal(2020)10.1016/j.bpj.2020.01.010

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12 citations

Yahor Savich, Rǎzvan L. Cornea, David D. Thomas, Megan R. McCarthy

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

Skeletal Muscle(2020)10.1186/s13395-020-0221-2

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44 citations

Cory W. Baumann, Robyn T. Rebbeck, Samantha L. Yuen, William M. Southern, James S. Hodges +5 more

RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays

Scientific Reports(2020)10.1038/s41598-020-58461-1

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0DataRank · unranked

37 citations

Daniel P. Singh, Kevyn A. Janicek, Donald M. Bers, David D. Thomas, Bradley S. Launikonis +2 more

Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules That Enhance Ca2+ Transport

Cells(2020)10.3390/cells9051170

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28 citations

Evan Kleinboehl, Samantha L. Yuen, Lauren N. Roelike, Bengt Svensson, Andrew R. Thompson +3 more

Met125 is essential for maintaining the structural integrity of calmodulin’s C-terminal domain

Scientific Reports(2020)10.1038/s41598-020-78270-w

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2 citations

Daniel K. Weber, Robyn T. Rebbeck, Rǎzvan L. Cornea, Gianluigi Veglia, David D. Thomas +1 more

Cardiac Myocyte Z-Line Calmodulin Is Mainly RyR2-Bound, and Reduction Is Arrhythmogenic and Occurs in Heart Failure

UNC Libraries(2020)10.17615/5ptv-vf42

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2 citations

Donald M. Bers, Bradley R. Fruen, Tetsuro Oda, Le Chen, Gerhard Meissner +6 more

Single-Polypeptide SERCA-Phospholamban Fused FRET Biosensor for High-throughput Cardiac-specific Drug Discovery

Biophysical Journal(2020)10.1016/j.bpj.2019.11.1771

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0 citations

Tory Schaaf, Samantha L. Yuen, Lauren N. Roelike, Bengt Svensson, Andrew R. Thompson +3 more

The transmembrane domain of DWORF activates SERCA directly; P15 and W22 residues are essential

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.18.303644

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0 citations

Daniel R. Stroik, Samantha L. Yuen, Evan Kleinboehl, Rǎzvan L. Cornea, David D. Thomas +1 more

High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development

Biophysical Journal(2020)10.1016/j.bpj.2019.11.3095

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0 citations

Gabrielle M. Evans, Kaja Rožman, Jacob Schwarz, Michael C. Wold, Marzena Baran +5 more

Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation

eLife(2021)10.7554/elife.66226

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44 citations

U. Venkateswara Reddy, Songlin Wang, Erik K. Larsen, Tata Gopinath, Martin Gustavsson +5 more

Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors

npj Parkinson s Disease(2021)10.1038/s41531-021-00195-6

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40 citations

Elly E. Liao, Mian Horvath, Prakriti Kalra, Karen Acosta, Malaney C. Young +11 more

The transmembrane peptide DWORF activates SERCA2a via dual mechanisms

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100412

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37 citations

Samantha L. Yuen, Daniel R. Stroik, Evan Kleinboehl, Rǎzvan L. Cornea, David D. Thomas +1 more

CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes

Journal of Molecular and Cellular Cardiology(2021)10.1016/j.yjmcc.2021.08.002

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14 citations

Christopher Y. Ko, Robyn T. Rebbeck, Sonya Baidar, Rǎzvan L. Cornea, Donald M. Bers +1 more

Sarcoplasmic Reticulum from Horse Gluteal Muscle Is Poised for Enhanced Calcium Transport

Veterinary Sciences(2021)10.3390/vetsci8120289

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6 citations

Bengt Svensson, Samuel F. Carlson, Zhenhui Chen, Rǎzvan L. Cornea, David D. Thomas +2 more

Identification of a dihydropyridine scaffold that blocks ryanodine receptors

iScience(2021)10.1016/j.isci.2021.103706

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3 citations

Robyn T. Rebbeck, Lindsey M. McGurran, Yasheng Yan, Thiago Arzua, Talia Frolkis +6 more

Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101412

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4 citations

Daniel P. Singh, Christopher Y. Ko, Roman Nikolaienko, Siobhan M. Wong King Yuen, Jacob Schwarz +12 more

Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.07.430153

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0DataRank · unranked

0 citations

Siobhan M. Wong King Yuen, Jacob Schwarz, Levy M. Treinen, Ching‐Chieh Tung, Robyn T. Rebbeck +7 more

High-Throughput Screening and Drug Development to Fix RyR Pathology

Biophysical Journal(2021)10.1016/j.bpj.2020.11.1089

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0DataRank · unranked

0 citations

Kaja Rožman, Gabrielle M. Evans, Jacob Schwarz, Marzena Baran, Courtney C. Aldrich +4 more

Synergistic FRET assays for drug discovery targeting RyR2 channels

Journal of Molecular and Cellular Cardiology(2022)10.1016/j.yjmcc.2022.04.002

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14 citations

Kenneth S. Ginsburg, Christopher Y. Ko, Anna Fasoli, Katherine Rusch, George F. Cai +5 more

New N-aryl-N-alkyl-thiophene-2-carboxamide compound enhances intracellular Ca2+ dynamics by increasing SERCA2a Ca2+ pumping

Biophysical Journal(2022)10.1016/j.bpj.2022.12.002

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9 citations

Elisa Bovo, Samantha L. Yuen, Levy M. Treinen, Kaja Berg, Courtney C. Aldrich +4 more

FRET-based trilateration resolves distinct structural states and transitions of calmodulin bound to ryanodine receptors

Biophysical Journal(2022)10.1016/j.bpj.2021.11.864

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0DataRank · unranked

0 citations

Robyn T. Rebbeck, Jingyan Zhang, Donald M. Bers, David D. Thomas, Rǎzvan L. Cornea +1 more

FRET assays for RyR-targeted drug discovery platforms

Biophysical Journal(2022)10.1016/j.bpj.2021.11.1857

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0DataRank · unranked

0 citations

Kaja Berg, Gabrielle M. Evans, Jacob Schwarz, Jake R. Trask, Lindsey M. McGurran +5 more

The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency

Journal of Molecular and Cellular Cardiology(2023)10.1016/j.yjmcc.2023.04.005

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32 citations

Daniel J. Blackwell, Samantha L. Yuen, Madelaine P. Thorpe, Jeffrey N. Johnston, Rǎzvan L. Cornea +2 more

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Scientific Reports(2023)10.1038/s41598-023-37704-x

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18 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

Regulation of cardiac calcium signaling by newly identified calcium pump modulators

Biochemical and Biophysical Research Communications(2023)10.1016/j.bbrc.2023.149136

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7 citations

Robyn T. Rebbeck, Osha Roopnarine, Rǎzvan L. Cornea, David D. Thomas, Aleksey V. Zima +1 more

Interaction of DWORF with SERCA and PLB as determined by EPR spectroscopy

Biochemical and Biophysical Research Communications(2023)10.1016/j.bbrc.2023.01.041

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13 citations

Osha Roopnarine, Rǎzvan L. Cornea, David D. Thomas, Mark Rustad

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

ACS Chemical Biology(2023)10.1021/acschembio.3c00376

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6 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State

International Journal of Molecular Sciences(2023)10.3390/ijms241612547

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0DataRank · unranked

4 citations

Florentin R. Nitu, Robyn T. Rebbeck, Lindsey M. McGurran, Tetsuro Oda, David D. Thomas +3 more

ent -Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547578

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3 citations

Tri Q., Kyung‐Soo Kim, Jacob Schwarz, Madelaine P. Thorpe, Daniel J. Blackwell +7 more

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.07.548138

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0DataRank · unranked

1 citations

Florentin R. Nitu, Robyn T. Rebbeck, Lindsey M. McGurran, Tetsuro Oda, David D. Thomas +3 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529557

N/A

0DataRank · unranked

0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Research Square(2023)10.21203/rs.3.rs-2596384/v1

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0DataRank · unranked

0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Phillip A. Bidwell +4 more

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.22.546083

N/A

0DataRank · unranked

0 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors

Nature Communications(2024)10.1038/s41467-024-48951-5

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7 citations

Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David D. Thomas, Donald M. Bers +2 more

Catecholaminergic polymorphic ventricular tachycardia–linked ryanodine receptor variants exhibit domain‐specific calcium leak and calmodulin affinity properties

The Journal of Physiology(2025)10.1113/jp288499

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6 citations

Xiaoqiong Dong, Ivanita Stefanon, Yi Yang, Eduardo Hertel Ribeiro, Bengt Svensson +7 more

Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110951

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1 citations

Elisa Bovo, Jonathan Solberg, Marzena Brinkmann, Levy M. Treinen, Andrew R. Thompson +9 more

Kinetics insight into the roles of the N- and C-lobes of calmodulin in RyR1 channel regulation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108258

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1 citations

Levy M. Treinen, Skylar J Mast, Megan R. McCarthy, Bengt Svensson, David D. Thomas +2 more

BPS2025 - SERCA2a-targeted drugs for treatment of heart failure: Medicinal chemistry development of a compound identified via high-throughput screening

Biophysical Journal(2025)10.1016/j.bpj.2024.11.1614

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0DataRank · unranked

0 citations

Marzena Brinkmann, Samantha L. Yuen, Tien Yin Wong, Kaja Berg, Rǎzvan L. Cornea +4 more

Development of activators for SERCA2a for heart failure treatments

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118408

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0DataRank · unranked

0 citations

Tsung-Yun Wong, Osha Roopnarine, Samantha L. Yuen, Kaja Berg, Rǎzvan L. Cornea +4 more