Pirro G. Hysi

Moorfields Eye Hospital NHS Foundation Trust

Also affiliated with University of Pittsburgh, King's College London, University of Exeter, Sørlandet Hospital Arendal, Centre for High Performance Computing, University College London

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.409Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1H NMR Spectroscopy Results From the UK Biobank

Investigative Ophthalmology & Visual Science(2023)10.1167/iovs.64.11.11

Top 45%

0.409DataRank

Top 45%9 citations

Anthony Khawaja, Janey L. Wiggs, Jihye Kim, Pirro G. Hysi, Tobias Elze +4 more

Papers

Driven by 51 papers — median percentile 55. Top paper: “Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia”.

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

Nature Genetics(2020)10.1038/s41588-020-0599-0

N/A

7.8DataRank · unranked

354 citations

Hélène Choquet, Anthony Khawaja, Robert Wojciechowski, Milly Tedja, Jie Yin +22 more

Rare and common genetic determinants of metabolic individuality and their effects on human health

Nature Medicine(2022)10.1038/s41591-022-02046-0

N/A

4.1DataRank · unranked

157 citations

Isobel D. Stewart, Victoria P. W. Au Yeung, Maik Pietzner, Johannes Raffler, Maria A. Wörheide +31 more

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

Communications Biology(2021)10.1038/s42003-021-01784-0

N/A

2.0DataRank · unranked

95 citations

Petra Liskova, Yelena Bykhovskaya, Bennet J. McComish, Alice E. Davidson, Chris F. Inglehearn +57 more

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

PLOS ONE(2017)10.1371/journal.pone.0167742

N/A

1.1DataRank · unranked

50 citations

Maria Sabater-Lleal, Daniel I. Chasman, Stella Trompet, Tarunveer S. Ahluwalia, Alexander Teumer +81 more

Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

Nature Communications(2024)10.1038/s41467-023-44380-y

N/A

1.0DataRank · unranked

64 citations

Wenjun Yan, John M. Rouhana, Aboozar Monovarfeshani, Xinyi Jiang, Puja A. Mehta +65 more

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Nature Communications(2021)10.1038/s41467-020-20851-4

N/A

0.933DataRank · unranked

503 citations

Eric Jorgenson, Pirro G. Hysi, Anthony Khawaja, Sarah A. Pendergrass, Xikun Han +93 more

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Nature Genetics(2020)10.1038/s41588-019-0556-y

N/A

0.886DataRank · unranked

367 citations

Xikun Han, Ayub Qassim, Mark Hassall, Jessica N. Cooke Bailey, Tyler G. Kinzy +54 more

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

Nature Genetics(2023)10.1038/s41588-023-01428-5

N/A

0.755DataRank · unranked

152 citations

Puya Gharahkhani, Andrew R. Hamel, Jue‐Sheng Ong, Miguel E. Rentería, Puja A. Mehta +24 more

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration

EBioMedicine(2023)10.1016/j.ebiom.2023.104551

N/A

0.749DataRank · unranked

33 citations

Samantha Sze‐Yee Lee, Ran Du, Yining Wang, Sander C. M. Kneepkens, Jason Charng +91 more

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

PLoS Genetics(2021)10.1371/journal.pgen.1009497

N/A

0.729DataRank · unranked

128 citations

Pirro G. Hysi, Tomas Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Anne Senabouth +29 more

Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma

Nature Communications(2024)10.1038/s41467-024-54301-2

N/A

0.704DataRank · unranked

15 citations

Weixiong He, Regina Yu, Xikun Han, Andrew R. Hamel, Terri L. Young +28 more

Genome-Wide Association Studies of Refractive Error and Myopia, Lessons Learned, and Implications for the Future

Investigative Opthalmology & Visual Science(2014)10.1167/iovs.14-14149

N/A

0.661DataRank · unranked

81 citations

Robert Wojciechowski, Jugnoo S. Rahi, Chris J. Hammond, Pirro G. Hysi

Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

Nature Communications(2023)10.1038/s41467-023-38466-w

N/A

0.614DataRank · unranked

59 citations

Jae H. Kang, Jessica Lasky‐Su, A. Heather Eliassen, Lisa Frueh, Clary B. Clish +7 more

Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank

Ophthalmology(2021)10.1016/j.ophtha.2021.03.007

N/A

0.604DataRank · unranked

55 citations

Sayuri Sekimitsu, Jiali Wang, Tobias Elze, Puya Gharahkhani, Brian Cole +36 more

A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness

Communications Biology(2020)10.1038/s42003-020-1037-7

N/A

0.598DataRank · unranked

53 citations

Ronald B. Melles, Jie Yin, Thomas J. Hoffmann, Khanh K. Thai, Mark Kvale +10 more

The Association of Alcohol Consumption with Glaucoma and Related Traits

Ophthalmology Glaucoma(2022)10.1016/j.ogla.2022.11.008

N/A

0.568DataRank · unranked

43 citations

Robert Luben, Alasdair Warwick, Kian Madjedi, Praveen J. Patel, Mahantesh I. Biradar +77 more

Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic etiology of ocular diseases

Human Molecular Genetics(2020)10.1093/hmg/ddaa155

N/A

0.557DataRank · unranked

40 citations

Anthony Khawaja, Pirro G. Hysi, Chris J. Hammond, Mark Simcoe

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity

Human Reproduction(2023)10.1093/humrep/dead247

N/A

0.505DataRank · unranked

28 citations

Scott D. Gordon, David L Duffy, Nikki Hubers, Sally Mortlock, Jeffrey J. Beck +52 more

Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders

EBioMedicine(2023)10.1016/j.ebiom.2023.104615

N/A

0.477DataRank · unranked

23 citations

Weixiong He, Jackson G. Thorp, Sahba Seddighi, Sean Mullany, Chris J. Hammond +13 more

Machine learning derived retinal pigment score from ophthalmic imaging shows ethnicity is not biology

Nature Communications(2025)10.1038/s41467-024-55198-7

N/A

0.449DataRank · unranked

19 citations

Abraham Olvera‐Barrios, Alasdair Warwick, Yue Wu, Kelsey V. Stuart, Mahantesh I. Biradar +87 more

Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma

Scientific Reports(2023)10.1038/s41598-023-43072-3

N/A

0.434DataRank · unranked

17 citations

Tyler G. Kinzy, Jessica N. Cooke Bailey, Zihe Xu, Pirro G. Hysi, Janey L. Wiggs +28 more

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.30.927822

N/A

0.416DataRank · unranked

15 citations

Eric Jorgenson, Pirro G. Hysi, Anthony Khawaja, Sarah A. Pendergrass, Xikun Han +73 more

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1H NMR Spectroscopy Results From the UK Biobank

Investigative Ophthalmology & Visual Science(2023)10.1167/iovs.64.11.11

Top 45%

0.409DataRank

Top 45%9 citations

Anthony Khawaja, Janey L. Wiggs, Jihye Kim, Pirro G. Hysi, Tobias Elze +4 more

Variants associated with HHIP expression have sex-differential effects on lung function

Wellcome Open Research(2020)10.12688/wellcomeopenres.15846.1

N/A

0.385DataRank · unranked

12 citations

Ma’en Obeidat, Carl Melbourne, Nick Shrine, Anna L. Guyatt, Catherine John +70 more

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank Optical Coherence Tomography images

medRxiv(2020)10.1101/2020.07.20.20157180

N/A

0.385DataRank · unranked

12 citations

Pirro G. Hysi, Tomas Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Denize Atan +25 more

Genetic Associations Between Smoking- and Glaucoma-Related Traits

Translational Vision Science & Technology(2023)10.1167/tvst.12.2.20

N/A

0.360DataRank · unranked

10 citations

Kelsey V. Stuart, Victor de Vries, Joëlle Vergroesen, Clara C. Cousins, Pirro G. Hysi +11 more

Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry

Journal of Investigative Dermatology(2020)10.1016/j.jid.2020.08.014

N/A

0.360DataRank · unranked

10 citations

Xin Li, Alessia Visconti, Maxim B. Freidin, Chiara Sacco, Simone Ribero +5 more

Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

eLife(2025)10.7554/elife.105576

N/A

0.345DataRank · unranked

9 citations

Nicholas Tolman, Ayellet V. Segrè, Kelsey V. Stuart, Oana A. Zeleznik, Neeru A. Vallabh +14 more

Variants associated with HHIP expression have sex-differential effects on lung function

Wellcome Open Research(2021)10.12688/wellcomeopenres.15846.2

N/A

0.306DataRank · unranked

5 citations

Ma’en Obeidat, Carl Melbourne, Nick Shrine, Anna L. Guyatt, Catherine John +70 more

Plasma metabolomics of primary open-angle glaucoma in three prospective US cohorts and the UK Biobank

medRxiv(2022)10.1101/2022.02.24.22271483

N/A

0.292DataRank · unranked

6 citations

Jae H. Kang, Jessica Lasky‐Su, A. Heather Eliassen, Lisa Frueh, Clary B. Clish +7 more

The Association of Urinary Sodium Excretion with Glaucoma and Related Traits in a Large United Kingdom Population

Ophthalmology Glaucoma(2024)10.1016/j.ogla.2024.04.010

N/A

0.269DataRank · unranked

5 citations

Mahantesh I. Biradar, Robert Luben, Neeraj Dhaun, Siegfried K. Wagner, Alasdair Warwick +79 more

Association analyses of rare variants identify two genes associated with refractive error

PLOS ONE(2022)10.1371/journal.pone.0272379

N/A

0.208DataRank · unranked

3 citations

Annechien E. G. Haarman, Anthony M. Musolf, Omar A. Mahroo, Jugnoo S. Rahi, Mario Falchi +9 more

Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation

Research Square(2023)10.21203/rs.3.rs-2762003/v1

N/A

0.165DataRank · unranked

2 citations

Bryan R. Gorman, Michael Francis, Cari L. Nealon, Christopher Halladay, Nalvi Duro +14 more

A multiethnic GWAS meta-analysis of 585,243 individuals identifies new risk loci associated with cataract and reveals sex-specific effects

medRxiv(2020)10.1101/2020.09.23.20200428

N/A

0DataRank · unranked

1 citations

Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuéllar-Partida, Wei Wang +6 more

The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts

Ophthalmology(2022)10.1016/j.ophtha.2022.04.023

N/A

0DataRank · unranked

40 citations

Kelsey V. Stuart, Sharon Chua, Robert Luben, Alasdair Warwick, Louis R. Pasquale +83 more

Convolutional neural network-based classification of glaucoma using optic radiation tissue properties

Communications Medicine(2024)10.1038/s43856-024-00496-w

N/A

0DataRank · unranked

18 citations

Adam Richie-Halford, Noah C. Benson, Sendy Caffarra, Julia P. Owen, Yue Wu +84 more

Association of Forced Vital Capacity with the Developmental Gene NCOR2

Tampere University Institutional Repository (Tampere University)(2024)10.17615/agfx-qc43

N/A

0DataRank · unranked

0 citations

Lies Lahousse, Henry Völzke, K. De Jong, Thor Aspelund, G. Eiríksdóttir +95 more

Rare variant analyses across multiethnic cohorts identify novel genes for refractive error

Research Square10.21203/rs.3.rs-846265/v1

N/A

0DataRank · unranked

0 citations

Annechien E. G. Haarman, Robert Luben, Jue‐Sheng Ong, Karina Patasova, Rolando Hernandez Trapero +31 more

Genome-Wide Insights Into the Genes and Pathways Shaping Human Foveal Development: Redefining the Genetic Landscape of Foveal Hypoplasia

Investigative Ophthalmology & Visual Science(2025)10.1167/iovs.66.12.22

N/A

0DataRank · unranked

5 citations

Ha-Jun Yoon, Alvin Lirio, Kayesha Coley, Jun Wang, Nick Shrine +16 more

Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging

Epigenetics(2025)10.1080/15592294.2025.2566496

N/A

0DataRank · unranked

1 citations

Omar A. Mahroo, Anthony Khawaja, Dorota Skowronska‐Krawczyk, David A. Mackey, Janey L. Wiggs +4 more

Author response: Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma

(2025)10.7554/elife.105576.2.sa0

N/A

0DataRank · unranked

0 citations

Nicholas Tolman, Ayellet V. Segrè, Kelsey V. Stuart, Oana A. Zeleznik, Neeru A. Vallabh +14 more

Genome-Wide Insights into the Genes and Pathways Shaping Human Foveal Development

medRxiv(2025)10.1101/2025.06.18.25329836

N/A

0DataRank · unranked

0 citations

Ha-Jun Yoon, Alvin Lirio, Kayesha Coley, Jun Wang, Nick Shrine +12 more

Genetically Estimated Ancestry and the Risk of Pre-Eclampsia

JACC Advances(2025)10.1016/j.jacadv.2025.102283

N/A

0DataRank · unranked

0 citations

Kypros H. Nicolaides, Argyro Syngelaki, Peter Dixon, Catherine Williamson, Maria Tsoukaki +5 more

A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation

Communications Biology(2024)10.1038/s42003-024-06046-3

N/A

0DataRank · unranked

22 citations

Michael Francis, Cari L. Nealon, Christopher Halladay, Nalvi Duro, Kyriacos Markianos +16 more

Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia

Human Molecular Genetics(2022)10.1093/hmg/ddac004

N/A

0DataRank · unranked

22 citations

Rosie Clark, Jiangtian Cui, Louise Terry, Karina Patasova, Annechien E. G. Haarman +7 more

The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation

Nature Communications(2021)10.1038/s41467-021-22639-6

N/A

0DataRank · unranked

21 citations

Wei Yuan, Fei Gao, Yudong Xia, Emma Bourne, Eva Wozniak +11 more

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

Nature Communications(2021)10.1038/s41467-021-23873-8

N/A

0DataRank · unranked

95 citations

Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuéllar-Partida, Wei Wang +6 more

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

UNC Libraries(2020)10.17615/644k-gr54

N/A

0DataRank · unranked

0 citations

Brian L. Yaspan, R. Rand Allingham, Alex W. Hewitt, Jie Jin Wang, Chiea Chuen Khor +75 more

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

UNC Libraries(2020)10.17615/nsqr-r935

N/A

0DataRank · unranked

0 citations

Yunlong Nie, Ma’en Obeidat, H. Schulz, Andrew J. Sandford, Albert V. Smith +27 more

Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function

UNC Libraries(2020)10.17615/2z2d-ex03

N/A

0DataRank · unranked

0 citations

Jason Z. Liu, Joanna Smolonska, Kristin M. Burkart, Paul Elliott, Alisa K. Manning +27 more

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Research at the University of Copenhagen (University of Copenhagen)(2020)10.17615/07fz-zt78

N/A

0DataRank · unranked

0 citations

Stavroula Kanoni, Ghazaleh Fatemifar, Tiina Laatikainen, Cristina Menni, Yingchang Lu +95 more

Pirro G. Hysi

Indexed papers

Top data-sharing exemplar

Papers