Mark T. Heise

University of North Carolina at Chapel Hill

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Complete genome sequences of 15 chikungunya virus isolates from Puerto Rico

UNC Libraries(2020)10.17615/q3wy-wf18

Top 100%

0DataRank

Top 100%0 citations

Mark T. Heise, Brenda Rivera, José F. Rodríguez‐Orengo, Nathaniel J. Moorman, Kristin A. Long +2 more

Papers

Driven by 124 papers — median percentile 0. Top paper: “A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge”.

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

UNC Libraries(2020)10.17615/e4vx-zc66

N/A

1.2DataRank · unranked

36 citations

Meagan Bolles, Ralph S. Baric, Martin T. Ferris, William K. Funkhouser, Alan C. Whitmore +6 more

β-d-N4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells

The Journal of Infectious Diseases(2021)10.1093/infdis/jiab247

N/A

0.856DataRank · unranked

300 citations

Collin S Hill, Sanjay Sarkar, Longping V. Tse, Blaide M D Woodburn, Raymond F. Schinazi +5 more

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3′UTR Variation in Chikungunya Virus

Journal of Virology(2020)10.1128/jvi.00701-20

N/A

0.581DataRank · unranked

47 citations

Kenneth S. Plante, Clayton R. Morrison, Katrina M. Kutchko, Wes Sanders, Kristin M. Long +10 more

A Mouse Model of Chikungunya Virus–Induced Musculoskeletal Inflammatory Disease: Evidence of Arthritis, Tenosynovitis, Myositis, and Persistence

UNC Libraries(2020)10.17615/xz3a-1e58

N/A

0.574DataRank · unranked

28 citations

Alina R. Lotstein, Mark T. Heise, Thomas E. Morrison, Alan C. Whitmore, Stephanie A. Montgomery +3 more

Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses

ACS Chemical Biology(2022)10.1021/acschembio.2c00378

N/A

0.505DataRank · unranked

28 citations

Rebekah J. Dickmander, Armin Bayati, Sharon Taft-Benz, Jeffery L. Smith, Carrow I. Wells +12 more

Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135004

N/A

0.489DataRank · unranked

25 citations

Sarah Entwistle, Caryn Willis, Steven Vensko, Wolfgang Beck, Jason Garness +15 more

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population

Vaccines(2024)10.3390/vaccines12010103

N/A

0.433DataRank · unranked

9 citations

Elizabeth J. Anderson, Brea K. Hampton, Breantié Parotti, Sanjay Sarkar, Sharon Taft-Benz +15 more

Virology under the Microscope—a Call for Rational Discourse

mSphere(2023)10.1128/msphere.00034-23

N/A

0.360DataRank · unranked

10 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice

G3 Genes Genomes Genetics(2024)10.1093/g3journal/jkae193

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0.312DataRank · unranked

7 citations

John Sebastian Sigmon, Jennifer Brennan, Chidima Ahulamibe, Michelle E Allen, Sam Ardery +32 more

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00351

N/A

0.292DataRank · unranked

6 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Virology under the Microscope—a Call for Rational Discourse

mBio(2023)10.1128/mbio.00188-23

N/A

0.241DataRank · unranked

4 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

Species-Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with In Vivo Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00825

N/A

0.241DataRank · unranked

4 citations

Abigail K. Mayo, Anirban Ghoshal, Sharon Taft-Benz, Elizabeth J. Anderson, Noah L. Morales +7 more

Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses

ChemRxiv(2022)10.26434/chemrxiv-2022-bj274

N/A

0.165DataRank · unranked

2 citations

Frances Potjewyd, Jeffrey L. Smith, Rebekah J. Dickmander, Armin Bayati, Stefanie Howell +7 more

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

Molecules(2024)10.3390/molecules29174158

N/A

0.165DataRank · unranked

2 citations

Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander +12 more

Mouse Models as Resources for Studying Infectious Diseases

UNC Libraries(2020)10.17615/5egs-j588

N/A

0DataRank · unranked

0 citations

Sanjay Sarkar, Mark T. Heise

Mannose Binding Lectin Is Required for Alphavirus-Induced Arthritis/Myositis

UNC Libraries(2020)10.17615/7qkb-p835

N/A

0DataRank · unranked

0 citations

Lara J. Herrero, Thomas E. Morrison, Linda Hueston, Robert J. Fraser, Alan C. Whitmore +6 more

Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants

UNC Libraries(2020)10.17615/72cq-r833

N/A

0DataRank · unranked

0 citations

Jack R. Harkema, Ande West, Raymond J. Pickles, Alan C. Whitmore, Deming, Damon +10 more

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

UNC Libraries(2020)10.17615/kzxb-9b93

N/A

0DataRank · unranked

0 citations

Xianchun Tang, Madeline G. Douglas, Kara Jensen, Anne Beall, Boyd L. Yount +5 more

Complete genome sequences of 15 chikungunya virus isolates from Puerto Rico

UNC Libraries(2020)10.17615/q3wy-wf18

Top 100%

0DataRank

Top 100%0 citations

Mark T. Heise, Brenda Rivera, José F. Rodríguez‐Orengo, Nathaniel J. Moorman, Kristin A. Long +2 more

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

UNC Libraries(2020)10.17615/36ww-wt38

N/A

0DataRank · unranked

0 citations

Matthew S. Miller, Xin Lin, Zhicheng Zhou, Wenqian He, Tingting Wang +6 more

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

UNC Libraries(2020)10.17615/z06v-7412

N/A

0DataRank · unranked

0 citations

Gary A. Churchill, Darla R. Miller, David W. Threadgill, Fernando Pardo‐Manuel de Villena, Richard Green +14 more

Glycosylation of Mouse DPP4 Plays a Role in Inhibiting Middle East Respiratory Syndrome Coronavirus Infection

UNC Libraries(2020)10.17615/x666-rc86

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0DataRank · unranked

0 citations

Adam S. Cockrell, Kayla M. Peck, Ralph S. Baric, Mark T. Heise, Trevor Scobey +1 more

Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants

UNC Libraries(2020)10.17615/qxh9-7054

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0DataRank · unranked

0 citations

Christina L. Burch, Mark T. Heise, Trevor Scobey, Kayla M. Peck, Jensen, Kara L. +2 more

Vaccination with DNA Plasmids Expressing Gn Coupled to C3d or Alphavirus Replicons Expressing Gn Protects Mice against Rift Valley Fever Virus

UNC Libraries(2020)10.17615/n5a6-j593

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0DataRank · unranked

0 citations

Ted M. Ross, Nitin Bhardwaj, Mark T. Heise

Modulation of Cellular Tropism and Innate Antiviral Response by Viral Glycans

UNC Libraries(2020)10.17615/zdar-bz15

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0DataRank · unranked

0 citations

Kristin M. Rogers, Mark T. Heise

Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein

UNC Libraries(2020)10.17615/kb8g-at17

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0DataRank · unranked

0 citations

Thomas E. Morrison, Robert E. Johnston, Reed S. Shabman, Stephanie A. Montgomery, Mehul S. Suthar +3 more

Development of a broadly accessible Venezuelan equine encephalitis virus replicon particle vaccine platform

UNC Libraries(2020)10.17615/fa7s-s338

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0DataRank · unranked

0 citations

Ralph S. Baric, Sudhakar Agnihothram, Mark T. Heise, Alexandra Schäfer, Jr. Yount +4 more

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

UNC Libraries(2020)10.17615/38n7-e665

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0DataRank · unranked

0 citations

Wataru Akahata, Jolanda M. Smit, Gary J. Nabel, Michael Diamond, Theodore C. Pierson +10 more

Ross River virus envelope glycans contribute to disease through activation of the host complement system

UNC Libraries(2020)10.17615/1c9p-vb05

N/A

0DataRank · unranked

0 citations

Bronwyn M. Gunn, Jennifer E. Jones, Sanjay Sarkar, Alan C. Whitmore, Thomas E. Morrison +3 more

An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo

UNC Libraries(2020)10.17615/yazd-wv98

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0DataRank · unranked

0 citations

Mark T. Heise, Martin T. Ferris, Yueh–Ming Loo, Michael Gale, Lance K. Blevins +1 more

MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV

UNC Libraries(2020)10.17615/9e08-dg24

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0DataRank · unranked

0 citations

Thomas E. Morrison, Mark T. Heise, Timothy P. Sheahan, Satoshi Uematsu, Ralph S. Baric +2 more

Genetic analysis of complex traits in the emerging Collaborative Cross

UNC Libraries(2020)10.17615/qyyg-x402

Top 100%

0DataRank

Top 100%0 citations

David A. Schwartz, David L. Aylor, Jill Steigerwalt, Martin T. Ferris, Elissa J. Chesler +27 more

A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

UNC Libraries(2020)10.17615/4z78-b985

N/A

0DataRank · unranked

0 citations

Virginia Godfrey, Andrew Hillhouse, Elizabeth P. Ryan, Mark T. Heise, Threadgill, Deborah S. +12 more

A Reverse Genetics Platform That Spans the Zika Virus Family Tree

UNC Libraries(2020)10.17615/9x3a-0b79

N/A

0DataRank · unranked

0 citations

Kayla M. Peck, Jessica A. Plante, Ralph S. Baric, Helen M. Lazear, Jesica Swanstrom +7 more

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

UNC Libraries(2020)10.17615/kt6q-wv72

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0DataRank · unranked

0 citations

Thomas E. Morrison, Kara Jensen, Sarah R. Leist, Vineet D. Menachery, Ralph S. Baric +4 more

Modeling Host Genetic Regulation of Influenza Pathogenesis in the Collaborative Cross

UNC Libraries(2020)10.17615/epjv-w292

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0DataRank · unranked

0 citations

Alan C. Whitmore, Shannon K. McWeeney, David L. Aylor, Timothy A. Bell, Lisa E. Gralinski +18 more

Annotation of long non-coding RNAs expressed in Collaborative Cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts

UNC Libraries(2020)10.17615/5png-6y33

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0DataRank · unranked

0 citations

Amie J. Eisfeld, Matthew J. W. Thomas, Yoshihiro Kawaoka, Laurence Josset, Michael G. Katze +10 more

A Protective Role for Complement C3 Protein during Pandemic 2009 H1N1 and H5N1 Influenza A Virus Infection

UNC Libraries(2020)10.17615/yr86-8f45

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0DataRank · unranked

0 citations

David Y. Dundore, Mark T. Heise, Stacey Schultz‐Cherry, Kevin O’Brien, Thomas E. Morrison

A Mouse-Adapted SARS-Coronavirus Causes Disease and Mortality in BALB/c Mice

UNC Libraries(2020)10.17615/5ehf-dw39

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0DataRank · unranked

0 citations

Tim Sheahan, Christopher D. Paddock, Mark T. Heise, Leatrice Vogel, Ralph S. Baric +8 more

High Rates of O’Nyong Nyong and Chikungunya Virus Transmission in Coastal Kenya

UNC Libraries(2020)10.17615/y65n-6z55

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0DataRank · unranked

0 citations

Julie Brichard, Uriel Kitron, Charles H. King, Eric M. Muchiri, Ginny Gildengorin +10 more

Severe Acute Respiratory Syndrome Coronavirus ORF6 Antagonizes STAT1 Function by Sequestering Nuclear Import Factors on the Rough Endoplasmic Reticulum/Golgi Membrane

UNC Libraries(2020)10.17615/s985-yf81

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0DataRank · unranked

0 citations

Peter Palese, Boyd L. Yount, Sarah A. Kopecky-Bromberg, Ralph S. Baric, Mark T. Heise +1 more

Synthetic Reconstruction of Zoonotic and Early Human Severe Acute Respiratory Syndrome Coronavirus Isolates That Produce Fatal Disease in Aged Mice

UNC Libraries(2020)10.17615/1tjz-xj23

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0DataRank · unranked

0 citations

Mark T. Heise, Amy Sims, Ralph S. Baric, Eric Donaldson, Mark J. Cameron +5 more

Expression Quantitative Trait Loci for Extreme Host Response to Influenza A in Pre-Collaborative Cross Mice

UNC Libraries(2020)10.17615/n0tk-5b74

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0DataRank · unranked

0 citations

Daniel Bottomly, Elizabeth Rosenzweig, Bart L Haagmans, Birgit Bradel-Tretheway, Martin T. Ferris +11 more

Natural Resistance-associated Macrophage Protein (NRAMP) is a cellular receptor for Sindbis virus in both insect and mammalian hosts

UNC Libraries(2020)10.17615/2t1m-7y59

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0DataRank · unranked

0 citations

Shelly Bambina, Richard W. Hardy, Daniel P. Beiting, Mark T. Heise, Susan R. Ross +5 more

Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection

PLoS Pathogens(2021)10.1371/journal.ppat.1009897

N/A

0DataRank · unranked

78 citations

Wanbo Tai, Victoria K. Baxter, Juan Shi, Yushun Wan, Xiujuan Zhang +16 more

Landscape and selection of vaccine epitopes in SARS-CoV-2

Genome Medicine(2021)10.1186/s13073-021-00910-1

N/A

0DataRank · unranked

59 citations

Kelly Olsen, Kaylee M. Gentry, Maria J. Sambade, Wolfgang Beck, Jason Garness +23 more

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

PLoS Pathogens(2021)10.1371/journal.ppat.1009287

N/A

0DataRank · unranked

32 citations

Jessica L. Swarts, Sarah R. Leist, Alexandra Schäfer, Vineet D. Menachery, Lisa E. Gralinski +10 more

Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses

PLoS neglected tropical diseases(2021)10.1371/journal.pntd.0009308

N/A

0DataRank · unranked

24 citations

Nicole N. Haese, Michael Denton, Takeshi Ando, Craig N. Kreklywich, Kiley Bonin +9 more

Novel modulators of p53-signaling encoded by unknown genes of emerging viruses

PLoS Pathogens(2021)10.1371/journal.ppat.1009033

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0DataRank · unranked

16 citations

Kathleen Corcoran, Aubrey Bailey, Kristin M. Long, Sharon Taft-Benz, Rachel L. Graham +9 more

Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication

mBio(2021)10.1128/mbio.03149-20

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0DataRank · unranked

9 citations

Kenneth H. Dinnon, Yixuan J. Hou, Timothy P. Sheahan, Mark T. Heise, Ralph S. Baric +1 more

Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection

UNC Libraries(2021)10.17615/48dn-p307

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0DataRank · unranked

3 citations

Jian Shang, Sharon Taft-Benz, Qibin Geng, Kenneth H. Dinnon, Victoria K. Baxter +16 more

A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding and cytopathogenicity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.24.469793

N/A

0DataRank · unranked

2 citations

Anna M. Schmoker, Boyd L. Yount, Philip Eisenhauer, Judith I. Keller, Clarissa Gold +13 more

Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein

UNC Libraries(2021)10.17615/yq96-sw95

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0DataRank · unranked

0 citations

Catherine C. Cruz, Mark T. Heise, Robert E. Johnston, Stephanie A. Montgomery, Thomas E. Morrison +3 more

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

UNC Libraries(2021)10.17615/ffgx-2r88

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0DataRank · unranked

0 citations

Jessica L. Swarts, Fernando Pardo‐Manuel de Villena, Martin T. Ferris, Mark T. Heise, Jessica B. Graham +10 more

Content and performance of the MiniMUGA genotyping array: A new tool to improve rigor and reproducibility in mouse research

UNC Libraries(2021)10.17615/tfcg-gt15

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0DataRank · unranked

0 citations

C. Franklin, B.J. Vilen, Lisa M. Tarantino, L. O apos Brien, Ralph S. Baric +64 more

Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection

UNC Libraries(2021)10.17615/cxvj-j536

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0DataRank · unranked

0 citations

Cole J. Batty, Eric M. Bachelder, Mark T. Heise, Kristy M. Ainslie

Characterization of Ross River Virus Tropism and Virus-Induced Inflammation in a Mouse Model of Viral Arthritis and Myositis

UNC Libraries(2021)10.17615/1yf3-zr41

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0DataRank · unranked

0 citations

Mark T. Heise, Thomas E. Morrison, Suresh Mahalingam, Alan C. Whitmore, Reed S. Shabman +1 more

An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo

UNC Libraries(2021)10.17615/5hd0-2332

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0DataRank · unranked

0 citations

Mark T. Heise, Yueh–Ming Loo, Michael Gale, Martin T. Ferris, Amy C. Wollish +1 more

Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model

UNC Libraries(2021)10.17615/26zb-5c57

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0DataRank · unranked

0 citations

Henri Jupille, Kristina A. Stoermer, Suresh Mahalingam, Mark T. Heise, Thomas E. Morrison +2 more

An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2

Cell Host & Microbe(2022)10.1016/j.chom.2022.12.005

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0DataRank · unranked

74 citations

Yuying Xie, Takanori Asakura, Dingka Song, Kaixin Liang, Sharon Taft-Benz +13 more

Genetic diversity of collaborative cross mice enables identification of novel rift valley fever virus encephalitis model

PLoS Pathogens(2022)10.1371/journal.ppat.1010649

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0DataRank · unranked

39 citations

Dominique J. Barbeau, Joshua Doyle, Ed Klein, Mark T. Heise, Martin T. Ferris +2 more

A Multitrait Locus Regulates Sarbecovirus Pathogenesis

mBio(2022)10.1128/mbio.01454-22

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0DataRank · unranked

25 citations

Sarah R. Leist, Lisa E. Gralinski, David R. Martinez, Emma S. Winkler, Kenichi Okuda +27 more

β-D-N4-hydroxycytidine (NHC) Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells

UNC Libraries(2022)10.17615/6dxx-nz91

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0DataRank · unranked

0 citations

Timothy P. Sheahan, Collin S Hill, Sanjay Sarkar, Raymond F. Schinazi, Mark T. Heise +5 more

Genetic diversity of collaborative cross mice enables identification of novel rift valley fever virus encephalitis model

UNC Libraries(2022)10.17615/tgpf-2181

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0DataRank · unranked

0 citations

Martin T. Ferris, Mark T. Heise, Anita K. McElroy, Joshua Doyle, Haley N. Cartwright +2 more

Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses

UNC Libraries(2022)10.17615/cph0-4s39

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0DataRank · unranked

0 citations

Sharon Taft-Benz, Nathaniel J. Moorman, Peter S. McPherson, Alison D. Axtman, David H. Drewry +8 more

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

Science Translational Medicine(2023)10.1126/scitranslmed.abq1533

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0DataRank · unranked

186 citations

Joseph M. Dybas, Hossein Fazelinia, Man S. Kim, Justin J. Frere, Yuanchao Zhang +46 more

Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection

Nature Communications(2023)10.1038/s41467-023-38238-6

N/A

0DataRank · unranked

96 citations

Muthu Saravanan Manoharan, Grace C. Lee, Lyle R. McKinnon, Justin A. Meunier, Maristella Steri +95 more

Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination

Cell Reports(2023)10.1016/j.celrep.2023.112326

N/A

0DataRank · unranked

51 citations

Sarah R. Leist, Kenneth H. Dinnon, Ande West, Kendra L. Gully, Elizabeth J. Anderson +19 more

The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection

Molecular Cell(2023)10.1016/j.molcel.2023.10.008

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0DataRank · unranked

28 citations

Frances Taschuk, Swechha M. Pokharel, Oleksandr Zginnyk, Max Ferretti, P Bailer +6 more

Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements

PLoS Pathogens(2023)10.1371/journal.ppat.1011168

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0DataRank · unranked

20 citations

Leigh A. Jania, Trang Thi Huyen Nguyen, David R. Martinez, Alexandra Schäfer, Nicholas Catanzaro +12 more

Effect of Viral Strain and Host Age on Clinical Disease and Viral Replication in Immunocompetent Mouse Models of Chikungunya Encephalomyelitis

Viruses(2023)10.3390/v15051057

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0DataRank · unranked

16 citations

Audrey C. Knight, Mark T. Heise, Victoria K. Baxter, Elizabeth J. Anderson

Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants

Journal of Virology(2023)10.1128/jvi.01070-23

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0DataRank · unranked

4 citations

Richard H.C. Huntwork, Gillian Q. Horn, Milite Abraha, Kathryn M. Hastie, Haoyang Li +14 more

Virology under the Microscope—a Call for Rational Discourse

Journal of Virology(2023)10.1128/jvi.00089-23

N/A

0DataRank · unranked

20 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.08.561395

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0DataRank · unranked

6 citations

Michael J. Topper, Katherine Beigel, Jeffrey Haltom, Amy Chadburn, Justin J. Frere +56 more

Chikungunya-virus-specific CD4 + T cells are associated with chronic chikungunya viral arthritic disease in humans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.20.567688

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0DataRank · unranked

3 citations

Rimjhim Agarwal, Fernanda Heloise Côrtes, Calvin Ha, John Villalpando, Izabella N. Castillo +9 more

Woodsmoke particle exposure prior to SARS-CoV-2 infection alters antiviral response gene expression in human nasal epithelial cells in a sex-dependent manner

UNC Libraries(2023)10.17615/w1df-8759

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0DataRank · unranked

0 citations

Neil E. Alexis, Ilona Jaspers, Mark T. Heise, Sharon Taft-Benz, Grant T. Billings +1 more

Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination

UNC Libraries(2023)10.17615/besf-dx19

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0DataRank · unranked

0 citations

Ande West, Ralph S. Baric, Brea K. Hampton, John M. Powers, Emily A. Madden +19 more

Adjuvant-dependent effects on the safety and efficacy of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus

Research Square(2023)10.21203/rs.3.rs-3401539/v1

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0DataRank · unranked

0 citations

Jacob A. Dillard, Sharon Taft-Benz, Audrey C. Knight, Elizabeth J. Anderson, Katia Pressey +26 more

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121

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0DataRank · unranked

31 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +24 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01346

N/A

0DataRank · unranked

28 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Meganathan Nandakumar, Anand Vala +12 more

A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants

Nature Communications(2024)10.1038/s41467-024-51535-y

N/A

0DataRank · unranked

22 citations

Wern Hann Ng, Eva Žusinaite, Joseph R. Freitas, Adam Taylor, Venugopal Yerragunta +28 more

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00962

N/A

0DataRank · unranked

18 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Jason W. Brown, Tammy M. Havener +13 more

Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus

Nature Communications(2024)10.1038/s41467-024-47450-x

N/A

0DataRank · unranked

15 citations

Sharon Taft-Benz, Audrey C. Knight, Elizabeth J. Anderson, Katia D. Pressey, Breantié Parotti +26 more

Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans

Virus Research(2024)10.1016/j.virusres.2024.199357

N/A

0DataRank · unranked

7 citations

Lisa E. Gralinski, Sarah R. Leist, Brea K. Hampton, Michael A. Mooney, Kara Jensen +20 more

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

Viruses(2024)10.3390/v16040636

N/A

0DataRank · unranked

4 citations

John D. Sears, Che-Kang Chang, Jane Burdick, Isabella Law, Wes Sanders +6 more

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production

Microorganisms(2024)10.3390/microorganisms12091794

N/A

0DataRank · unranked

3 citations

Emily A. Madden, J Boussier, Diana Erazo, Wes Sanders, Thomas Vallet +5 more

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586341

N/A

0DataRank · unranked

7 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +20 more

The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.29.582794

N/A

0DataRank · unranked

2 citations

John Sebastian Sigmon, Jennifer Brennan, Chidima Ahulamibe, Michelle E Allen, Ralph S. Baric +28 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.12.598722

N/A

0DataRank · unranked

2 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Eric M. Merten, John D. Sears +7 more

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

ChemRxiv(2024)10.26434/chemrxiv-2024-h2x2b

N/A

0DataRank · unranked

0 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Joshua B. Brown, Tammy M. Havener +13 more

Universal Competition Assay by Nanopore Sequencing (U-CAN-Seq) v1

(2024)10.17504/protocols.io.kqdg3xjdzg25/v1

N/A

0DataRank · unranked

0 citations

John D. Sears, Wes Sanders, Che-Kang Chang, Paul W. Sylvester, Colton L. Linnertz +4 more

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population

UNC Libraries(2024)10.17615/33ab-w788

N/A

0DataRank · unranked

0 citations

Sharon Taft-Benz, Fernando Pardo‐Manuel de Villena, Pablo Hock, Emily A. Madden, Martin T. Ferris +15 more

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

UNC Libraries(2024)10.17615/k948-9046

N/A

0DataRank · unranked

0 citations

Paul W. Sylvester, Martin T. Ferris, Wes Sanders, Jennifer Diaz, Isabella Law +6 more

Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus

UNC Libraries(2024)10.17615/c2sq-w405

N/A

0DataRank · unranked

0 citations

Stephanie A. Montgomery, David R. Martinez, Ralph S. Baric, Victoria K. Baxter, Emily A. Madden +26 more

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3'UTR Variation in Chikungunya Virus.

UNC Libraries(2024)10.17615/mxrz-yq05

N/A

0DataRank · unranked

0 citations

N.J. Moorman, Mark T. Heise, Sharon Taft-Benz, Emily A. Madden, Grace L. Reynolds +10 more

The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice

UNC Libraries(2024)10.17615/vjs1-0445

N/A

0DataRank · unranked

0 citations

Kelsey E. Noll, David Truong Nguyen, Megan K. Proulx, Marta C Cruz Cisneros, Pablo Hock +32 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635

N/A

0DataRank · unranked

9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Scientific Reports(2025)10.1038/s41598-025-91673-x

N/A

0DataRank · unranked

9 citations

Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears +22 more

Broadly active intranasal influenza vaccine with a nanocomplex particulate adjuvant targeting mast cells and toll-like receptor 9

Journal of Controlled Release(2025)10.1016/j.jconrel.2025.113855

N/A

0DataRank · unranked

3 citations

Dylan A. Hendy, Erik S. Pena, Grace L. Williamson, Connor T. Murphy, Nicole Rose Lukesh +12 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01802

N/A

0DataRank · unranked

2 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650479

N/A

0DataRank · unranked

1 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.30.662352

N/A

0DataRank · unranked

1 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

Species Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with in Vivo Anti-alphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.13.632788

N/A

0DataRank · unranked

0 citations

Abigail K. Mayo, Anirban Ghoshal, Sharon Taft-Benz, Elizabeth J. Anderson, Noah L. Morales +7 more

Identification of Spirodioxolane nsP2 Helicase Inhibitors with Antialphaviral Activity

ChemRxiv(2025)10.26434/chemrxiv-2025-mfts7

N/A

0DataRank · unranked

0 citations

John D. Sears, Muthu Bose Ramalingam, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

Insulin-deficient diabetes impairs vaccine-mediated antibody and germinal center B-cell formation in mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.24.677144

N/A

0DataRank · unranked

0 citations

Pablo Ariel, Mark T. Heise, Lance R. Thurlow, Christopher J. Genito

The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection

UNC Libraries(2025)10.17615/g75h-dc83

N/A

0DataRank · unranked

0 citations

Oleksandr Zginnyk, Frances Taschuk, Emily A. Madden, P Bailer, Sara Cherry +6 more

Development of a virulent O'nyong'nyong challenge model to determine heterologous protection mediated by a hydrogen peroxide-inactivated chikungunya virus vaccine.

UNC Libraries(2025)10.17615/vpvc-7h13

N/A

0DataRank · unranked

0 citations

Magdalene M. Streblow, Michael Denton, Gauthami Sulgey, Mark T. Heise, Dawn K. Slifka +9 more

Adaptive immune response to West Nile virus infection in the Collaborative Cross mouse model: A database of cellular phenotypes and Quantitative Trait Loci

Scientific Data(2025)10.1038/s41597-025-06293-x

N/A

0DataRank · unranked

0 citations

Jessica B. Graham, Sophia Jeng, Jessica L. Swarts, Martin T. Ferris, Mark T. Heise +5 more

Identification of spirodioxolane nsP2 helicase inhibitors with antialphaviral activity

RSC Medicinal Chemistry(2025)10.1039/d5md00772k

N/A

0DataRank · unranked

0 citations

John D. Sears, M. Bose, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research

Genetics(2020)10.1534/genetics.120.303596

N/A

0DataRank · unranked

112 citations

Matthew W Blanchard, Ralph S. Baric, Timothy A. Bell, Jennifer Brennan, Gudrun A. Brockmann +64 more

Novel computational pipeline to identify target sites for broad spectrum antiviral drugs

Antiviral Research(2025)10.1016/j.antiviral.2025.106322

N/A

0DataRank · unranked

0 citations

Konstantin Popov, P. A. Sylvester, Rebekah J. Dickmander, Jennifer Loome-Diaz, Che-Kang Chang +14 more

Immunopathogenesis of alphaviruses

Advances in virus research(2020)10.1016/bs.aivir.2020.06.002

N/A

0DataRank · unranked

57 citations

Mark T. Heise, Victoria K. Baxter

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

UNC Libraries(2020)10.17615/v24k-gj40

N/A

0DataRank · unranked

54 citations

Alexandra Schäfer, Alan C. Whitmore, Sudhakar Agnihothram, Michael G. Katze, Ralph S. Baric +2 more

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Cell Reports(2020)10.1016/j.celrep.2020.107587

N/A

0DataRank · unranked

50 citations

Alan C. Whitmore, Ande West, Mary K. McCarthy, Clayton R. Morrison, Kenneth S. Plante +18 more

Mouse Dipeptidyl Peptidase 4 Is Not a Functional Receptor for Middle East Respiratory Syndrome Coronavirus Infection

UNC Libraries(2020)10.17615/v26a-qn52

N/A

0DataRank · unranked

7 citations

Boyd L. Yount, Ralph S. Baric, Sudhakar Agnihothram, Trevor Scobey, Mark T. Heise +3 more

A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/dwgs-ep23

N/A

0DataRank · unranked

3 citations

Eric Donaldson, Arun K. Ghosh, Robin Gopal, Trevor Scobey, Maria Zambon +14 more

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

UNC Libraries(2020)10.17615/h1fd-8931

N/A

0DataRank · unranked

3 citations

Nurgun Kose, Pankaj Pal, Michael Diamond, Benjamin J. Doranz, Charles E. McGee +15 more

Bayesian Diallel analysis reveals MX1-dependent and MX1-independent effects on response to influenza a virus in mice

UNC Libraries(2020)10.17615/0ed7-d785

N/A

0DataRank · unranked

2 citations

Ande West, Paul L. Maurizio, Mark T. Heise, Ralph S. Baric, Ginger D. Shaw +11 more

Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus

UNC Libraries(2020)10.17615/y0zf-jc86

N/A

0DataRank · unranked

4 citations

Mark T. Heise, Barry Rockx, Ralph S. Baric, Martin T. Ferris, Timothy P. Sheahan +8 more

Genomic Profiling of Collaborative Cross Founder Mice Infected with Respiratory Viruses Reveals Novel Transcripts and Infection-Related Strain-Specific Gene and Isoform Expression

UNC Libraries(2020)10.17615/eja8-sy07

N/A

0DataRank · unranked

1 citations

Alan C. Whitmore, Michael G. Katze, Ralph S. Baric, Juliet Morrison, Martin T. Ferris +9 more

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.19.957118

N/A

0DataRank · unranked

18 citations

Kenneth S. Plante, Lisa E. Gralinski, Anne Beall, Martin T. Ferris, Daniel Bottomly +6 more

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.21.306837

N/A

0DataRank · unranked

1 citations

Jessica L. Swarts, Sarah R. Leist, Alexandra Schäfer, Vineet D. Menachery, Lisa E. Gralinski +10 more

478 Translation of a therapeutic neoantigen vaccine workflow to SARS-CoV-2 vaccine development

Regular and Young Investigator Award Abstracts(2020)10.1136/jitc-2020-sitc2020.0478

N/A

0DataRank · unranked

0 citations

Sarah Entwistle, Caryn Willis, Steven Vensko, Wolfgang Beck, Jason Garness +20 more

Vaccine-induced skewing of t cell responses protects against chikungunya virus disease

UNC Libraries(2020)10.17615/wez2-yx46

N/A

0DataRank · unranked

0 citations

Rebecca M. Broeckel, Patricia Smith, Igor P. Dmitriev, Victor R. DeFilippis, Ilhem Messaoudi +9 more

Mark T. Heise

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