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Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121Source: DataRank Database

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach is a research paper published in Proceedings of the National Academy of Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 31 times.

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Scored on demand from live citation data

Open Access31 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 13.13)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (29)

John D. Sears ORCID,Tina M. Leisner ORCID,P. Brian Hardy,Anirban Ghoshal ORCID,Mohammad Anwar Hossain ORCID

Live enrichment

PubMed:39388272 PMC:PMC11494320 OpenAlex:https://openalex.org/W4403298165

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: NIH 1U19AI171292-01

HHS | NIH | National Cancer Institute

Grant: 2P30CA016086-45

NIH HHS

Grant: S10 OD032476

NCI NIH HHS

Grant: P30 CA016086

NIAID NIH HHS

Grant: U19 AI171292

European Commission

Grant: 875510

EUbOPEN: Enabling and Unlocking biology in the OPEN

FWCI

13.13

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2409166121

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2409166121

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2409166121

journalhttps://doi.org/10.1073/pnas.2409166121

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39388272

Fields of Study

Mosquito-borne diseases and controlHIV Research and TreatmentVirology and Viral Diseases0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsAntiviral AgentsChikungunya virusCysteine EndopeptidasesHumansProtease InhibitorsSulfonesVirus ReplicationChikungunya Fever

Keywords

ChikungunyaVirologyFragment (logic)Identification (biology)Protease inhibitor (pharmacology)VirusComputational biologyBiologyComputer scienceAlgorithmFragmentChikungunya virusdrug discoveryCovalent InhibitorNsp2 ProteaseCysteine EndopeptidasesHumansAnimalsChikungunya FeverProtease InhibitorsSulfonesBiological SciencesVirus ReplicationAntiviral Agents

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

FAIR Checklist

Authors (29)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)