Lyn‐Marié Birkholtz

Also affiliated with Institute for Sustainable Development, University of Pretoria

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 17 papers. Top paper: “Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases”.

Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases

Communications Biology(2020)10.1038/s42003-020-01424-z

N/A

0.529DataRank · unranked

33 citations

Clarissa Abrie, Keith Al‐Hasani, Mitchell B. Batty, Victoria Corey, Anne N. Cowell +6 more

Machine Learning Approaches Identify Chemical Features for Stage-Specific Antimalarial Compounds

ACS Omega(2023)10.1021/acsomega.3c05664

N/A

0.373DataRank · unranked

11 citations

Gemma Turon, Miquel Duran‐Frigola, Nelishia Pillay, Lyn‐Marié Birkholtz, Ashleigh van Heerden

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission

Science Advances(2024)10.1126/sciadv.adq1383

N/A

0.241DataRank · unranked

4 citations

Antima Gupta, Laura Drought, Avnish Patel, John Okombo, Mariëtte van der Watt +42 more

Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01291-23

N/A

0.165DataRank · unranked

2 citations

Mariëtte van der Watt, Hazel Gwarinda, Ashleigh van Heerden, Bryan Greenhouse, Didier Leroy +3 more

A dynamic and combinatorial histone code drives malaria parasite asexual and sexual development

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.19.452879

N/A

0.104DataRank · unranked

1 citations

Mariel Coradin, Mariel Mendoza, Janette Reader, Simone Sidoli, Benjamin A. García +2 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Research Square(2024)10.21203/rs.3.rs-5412515/v1

N/A

0.104DataRank · unranked

1 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies–Activities Against Blood Stage P. falciparum Including PfKI3 C580Y Mutants and Liver Stage P. berghei Parasites

Frontiers in Chemistry(2020)10.3389/fchem.2019.00901

N/A

0DataRank · unranked

22 citations

Vivian Padín-Irizarry, Mariëtte van der Watt, Janette Reader, Wilna Liebenberg, Lubbe Wiesner +8 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

npj Drug Discovery.(2025)10.1038/s44386-025-00006-5

N/A

0DataRank · unranked

11 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Synthesis and SAR Studies of Acyl-Thiourea Platinum(II) Complexes Yield Analogs with Dual-Stage Antiplasmodium Activity

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.4c00545

N/A

0DataRank · unranked

5 citations

Dina Coertzen, Sizwe Tshabalala, Meta Leshabane, Shanté da Rocha, Mathew Njoroge +7 more

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01417

N/A

0DataRank · unranked

3 citations

Mmakwena M. Mmonwa, Dina Coertzen, Liezl Krugmann, Nicolaas Salomane, Meta Leshabane +18 more

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Angewandte Chemie International Edition(2025)10.1002/anie.202425206

N/A

0DataRank · unranked

6 citations

Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy +29 more

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01154

N/A

0DataRank · unranked

22 citations

Donald Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S. Sypu +30 more

Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products

International Journal for Parasitology Drugs and Drug Resistance(2020)10.1016/j.ijpddr.2020.05.003

N/A

0DataRank · unranked

27 citations

William Shamburger, Mariëtte van der Watt, Janette Reader, Ana Carolina C. de Sousa, Timothy J. Egan +4 more

A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development

Molecular & Cellular Proteomics(2022)10.1016/j.mcpro.2022.100199

N/A

0DataRank · unranked

22 citations

Mariel Coradin, Mariel Mendoza, Janette Reader, Simone Sidoli, Benjamin A. García +2 more

Adsorption to the Surface of Hemozoin Crystals: Structure‐Based Design and Synthesis of Amino‐Phenoxazine β‐Hematin Inhibitors

ChemMedChem(2022)10.1002/cmdc.202200139

N/A

0DataRank · unranked

11 citations

Leigh Loots, Michélle Kok, Marianne de Villiers, Janette Reader, Lyn‐Marié Birkholtz +3 more

Synthesis and Testing of Analogs of the Tuberculosis Drug SQ109 Against Bacteria and Protozoa: Identification of Lead Compounds Against Mycobacterium abscessus and Malaria

ChemRxiv(2022)10.26434/chemrxiv-2022-xm94p

N/A

0DataRank · unranked

0 citations

Satish R. Malwal, Nadine Álvarez, Zijun Gao, Mohammad Moniruzzaman, Svitlana Babii +28 more

Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00537

N/A

0DataRank · unranked

20 citations

Satish R. Malwal, Nadine Álvarez, Zijun Gao, Mohammad Moniruzzaman, Svitlana Babii +28 more