🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Melissa E. Hughes

Yale Cancer Center

ORCID: 0000-0001-6190-9101

Also affiliated with Yale University, Dana-Farber Cancer Institute, Dana-Farber Brigham Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile
1.3Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine(2024)10.1038/s41591-024-03215-z
Top 15%
1.3DataRank
Top 15%91 citations

Daniel L. Abravanel, Åsa Segerstolpe, Timothy R. Blosser, Yury Goltsev, Yi Cui +57 more

Papers

Driven by 14 papers — median percentile 85. Top paper: “A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features”.

A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine(2024)10.1038/s41591-024-03215-z
Top 15%
1.3DataRank
Top 15%91 citations

Daniel L. Abravanel, Åsa Segerstolpe, Timothy R. Blosser, Yury Goltsev, Yi Cui +57 more

STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

Nature Communications(2022)10.1038/s41467-022-30568-1
N/A
0.832DataRank · unranked
255 citations

Johann S. Bergholz, Liya Ding, Ziying Lin, Sheheryar Kabraji, Melissa E. Hughes +14 more

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer

Annals of Oncology(2020)10.1016/j.annonc.2020.02.008
N/A
0.759DataRank · unranked
157 citations

Ofir Cohen, Bose Kochupurakkal, D. Kim, Connor E. Dunn, Jorge Buendia +20 more

Liquid biopsy epigenomic profiling for cancer subtyping

Nature Medicine(2023)10.1038/s41591-023-02605-z
N/A
0.722DataRank · unranked
122 citations

Ji-Heui Seo, Matthew P. Davidsohn, Brad Fortunato, Karl Semaan, Shahabbedin Sotudian +38 more

Clinical outcomes of early-stage triple-negative breast cancer after neoadjuvant chemotherapy according to HER2-low status☆

ESMO Open(2024)10.1016/j.esmoop.2024.103973
N/A
0.385DataRank · unranked
12 citations

Danielle Brandes Zakon, Qingchun Jin, Ava Strahan, Melissa Grimm, Melissa E. Hughes +15 more

Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer

npj Breast Cancer(2024)10.1038/s41523-023-00605-3
N/A
0.360DataRank · unranked
10 citations

Jia‐Ren Lin, Ricardo Pastorello, Ziming Du, Yu-An Chen, Madeline G Townsend +17 more

Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2

ESMO Open(2025)10.1016/j.esmoop.2024.104111
N/A
0.282DataRank · unranked
5 citations

P. Tarantino, Rong Li, Albert Grinshpun, Hersh Gupta, Melissa E. Hughes +12 more

Pure estrogen receptor antagonists potentiate capecitabine activity in ESR1-mutant breast cancer

npj Breast Cancer(2024)10.1038/s41523-024-00647-1
N/A
0.241DataRank · unranked
4 citations

Douglas Russo, Wen Ma, Ana Verma, Francisco Hermida-Prado, Shira Sherman +13 more

Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine(2025)10.1038/s41591-025-03665-z
N/A
0.104DataRank · unranked
1 citations

Daniel L. Abravanel, Åsa Segerstolpe, Timothy R. Blosser, Yury Goltsev, Yi Cui +57 more

Genomic profiling of breast cancer brain metastases reveals targetable alterations.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.2525
N/A
0.104DataRank · unranked
1 citations

Liam F. Spurr, Melissa E. Hughes, Yvonne Y. Li, José Pablo Leone, Ana C. Garrido-Castro +8 more

Adjuvant capecitabine in patients with triple-negative breast cancer after neoadjuvant chemotherapy

ESMO Open(2025)10.1016/j.esmoop.2025.105568
N/A
0.104DataRank · unranked
1 citations

Qi Jin, Agepati S. Raghavendra, Danielle Brandes Zakon, Melissa Grimm, Melissa E. Hughes +16 more

Humoral immune responses to the second dose of a COVID-19 mRNA vaccine in cancer patients undergoing treatment

Human Vaccines & Immunotherapeutics(2025)10.1080/21645515.2025.2570963
N/A
0.104DataRank · unranked
1 citations

Troy J. Kemp, Nancy Roche, Katarzyna Haynesworth, Sarah Loftus, Benjamin J. Borski +10 more

Data from Preclinical and Clinical Efficacy of Trastuzumab Deruxtecan in Breast Cancer Brain Metastases

(2023)10.1158/1078-0432.c.6532872
N/A
0DataRank · unranked
0 citations

Jing Ni, Sarah Sammons, Tianyu Li, Amanda E.D. Van Swearingen, Yanzhi Wang +14 more

The Effects of Diabetes and Glycemic Control on Cancer Outcomes in Individuals With Metastatic Breast Cancer

The Journal of Clinical Endocrinology & Metabolism(2022)10.1210/clinem/dgac375
N/A
0DataRank · unranked
16 citations

Melissa E. Hughes, Julia C. Harrod, Janet Files, Greg Kirkner, Lauren Buckley +5 more