Brian C. Smith

Physics and AstronomyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis”.

Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100809

N/A

0.373DataRank · unranked

11 citations

Jackie Chang, Vaya Chen, M. A. Beg, Wenxin Huang, Lance Vick +21 more

BET bromodomain inhibitors attenuate transcription of a subset of IL-1-induced NF-κB targets that promote inflammation in β-cells

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110358

N/A

0.258DataRank · unranked

3 citations

Savannah J. Makowski, Paul Sidlowski, Karina Bursch, John A. Corbett, Brian C. Smith +1 more

Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.07.556574

N/A

0.104DataRank · unranked

1 citations

Jackie Chang, Wenjing Chen, M. A. Beg, Wenxin Huang, Lance Vick +22 more

Sirtuin Oxidative Post-translational Modifications

Frontiers in Physiology(2021)10.3389/fphys.2021.763417

N/A

0DataRank · unranked

25 citations

Sarah L. Wynia‐Smith, Brian C. Smith, Kelsey Kalous

Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12

ACS Medicinal Chemistry Letters(2021)10.1021/acsmedchemlett.1c00388

N/A

0DataRank · unranked

7 citations

Anthony E. Getschman, Tyler G. Fenske, Brian F. Volkman, Brian C. Smith, Daniel J. Sprague

BET bromodomain inhibitors diminish IL‐1B‐induced transcription of NF‐κB target genes

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04284

N/A

0DataRank · unranked

1 citations

Sarah L. Wynia‐Smith, Rachel Jones Lipinski, Brian C. Smith, Joshua Nord

Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1‐like ( DOT1L ) and partnering complexes involved in leukemogenesis

Proteins Structure Function and Bioinformatics(2021)10.1002/prot.26219

N/A

0DataRank · unranked

5 citations

Young‐In Chi, Thiago M. de Assuncao, Elise Leverence, Swarnendu Tripathi, Nikita R. Dsouza +7 more

Discovering and Exploiting Selectivity in Bromodomain Recognition of Epigenetic Lysine Acylation

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04850

N/A

0DataRank · unranked

0 citations

Brian C. Smith

BET Bromodomain Inhibition Results in the Conserved Upregulation of Sirtuin 1

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04110

N/A

0DataRank · unranked

0 citations

Sarah L. Wynia‐Smith, Joshua Nord, Brian C. Smith, Rachel Jones Lipinski

Mitigation of Injury from Myocardial Infarction by TH1834, an Inhibitor of the Acetyltransferase Tip60

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.09.467996

N/A

0DataRank · unranked

0 citations

Tina C. Wan, Katherine Kulik, Amelia Lauth, Brian C. Smith, John Lough +2 more

Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00864

N/A

0DataRank · unranked

20 citations

Raymundo Nuñez, Brayden P. Strohmier, Karina Bursch, Christopher J. Goetz, Michael D. Olp +10 more

Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury

Disease Models & Mechanisms(2022)10.1242/dmm.049786

N/A

0DataRank · unranked

18 citations

Tina C. Wan, Katherine Kulik, Amelia Lauth, Brian C. Smith, John Lough +2 more

N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells

Frontiers in Endocrinology(2022)10.3389/fendo.2022.923925

N/A

0DataRank · unranked

15 citations

Sarah L. Wynia‐Smith, Alyssa L Gehant, Rachel A. Jones, Aaron Naatz, Inmaculada Rioja +4 more

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.04.028

N/A

0DataRank · unranked

12 citations

Timothy J. Stodola, Thiago M. de Assuncao, Elise Leverence, Brian C. Smith, Brian F. Volkman +5 more

Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

iScience(2022)10.1016/j.isci.2022.105670

N/A

0DataRank · unranked

10 citations

Robert F. Keyes, Donna McAllister, Francis C. Peterson, Ishaque P. Kadamberi, Daniel J. Sprague +4 more

Characterization of Dual-Acting A3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gαi3 and GαoA Isoprotein Activation

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00076

N/A

0DataRank · unranked

13 citations

Lucas B. Fallot, Tina C. Wan, Robert F. Keyes, R. Rama Suresh, Amy C. Rothwell +6 more

Characterization of Novel A 3 Adenosine Receptor Allosteric Modulators

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.00r64

N/A

0DataRank · unranked

0 citations

Tina C. Wan, Lucas B. Fallot, Robert F. Keyes, R. R. Suresh, Amy C. Rothwell +6 more

Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.03.034

N/A

0DataRank · unranked

30 citations

Joyce Chiu, Christina Scartelli, Nathan Ponzar, Sachin Patel, Anika Patel +8 more

Cysteine and methionine oxidation in thrombotic disorders

Current Opinion in Chemical Biology(2023)10.1016/j.cbpa.2023.102350

N/A

0DataRank · unranked

28 citations

Brian C. Smith, Moua Yang

Fragment-based screening by protein-detected NMR spectroscopy

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.06.018

N/A

0DataRank · unranked

16 citations

Raymundo Nuñez, Davin R. Jensen, Angela L. Zhou, Francis C. Peterson, R. Blake Hill +3 more

Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00671

N/A

0DataRank · unranked

15 citations

Chad A. Maschinot, Sijie Wang, Surbhi Sood, Luisa F. Baracaldo-Lancheros, Brayden P. Strohmier +4 more

Analysis of continuous enzyme kinetic data using ICEKAT

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.06.019

N/A

0DataRank · unranked

10 citations

Michael D. Olp, Brian C. Smith, Karina Bursch

Fragment-based drug discovery of small molecule ligands for the human chemokine CCL28

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.02.004

N/A

0DataRank · unranked

7 citations

Davin R. Jensen, Francis C. Peterson, Monica A. Thomas, Roman R. Schlimgen, Michael B. Dwinell +3 more

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.10.003

N/A

0DataRank · unranked

8 citations

Neshatul Haque, Jessica B. Wagenknecht, Davin R. Jensen, Guadalupe Esparza, Elise Leverence +8 more

Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction

Frontiers in Genetics(2023)10.3389/fgene.2023.1291307

N/A

0DataRank · unranked

6 citations

Young‐In Chi, Jose Lizarraga Mazaba, Neshatul Haque, Jessica B. Wagenknecht, Brian C. Smith +6 more

Identification of Protein Targets of S-Nitroso-Coenzyme A-Mediated S-Nitrosation Using Chemoproteomics

ACS Chemical Biology(2023)10.1021/acschembio.3c00654

N/A

0DataRank · unranked

2 citations

Sarah L. Wynia‐Smith, James David McCoy, Brian C. Smith, Eranthie Weerapana, Julia A. Falco

A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.10.022

N/A

0DataRank · unranked

2 citations

Salomão Dória Jorge, Davin R. Jensen, Brian C. Smith, Brian F. Volkman, Angela Mathison +4 more

Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.28.536249

N/A

0DataRank · unranked

2 citations

Neshatul Haque, Jessica B. Wagenknecht, Davin R. Jensen, Guadalupe V. Esparza, Elise Leverence +8 more

Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection

STAR Protocols(2023)10.1016/j.xpro.2023.102437

N/A

0DataRank · unranked

0 citations

Donna McAllister, Michael B. Dwinell, Brian C. Smith, Robert F. Keyes

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.06.556558

N/A

0DataRank · unranked

0 citations

Salomão Dória Jorge, Davin R. Jensen, Brian C. Smith, Brian F. Volkman, Angela Mathison +4 more

Current Trends in Sirtuin Activator and Inhibitor Development

Molecules(2024)10.3390/molecules29051185

N/A

0DataRank · unranked

54 citations

Christopher J. Goetz, Brian C. Smith, Karina Bursch

The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation

ACS Chemical Biology(2024)10.1021/acschembio.4c00248

N/A

0DataRank · unranked

49 citations

Paul Sidlowski, Erica A. Steen, Sarah L. Wynia‐Smith, Daniel J. Sprague, Robert F. Keyes +2 more

Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7

Molecular Pharmacology(2024)10.1124/molpharm.123.000784

N/A

0DataRank · unranked

10 citations

Matteo Pavan, Veronica Salmaso, Robert F. Keyes, Tina C. Wan, Balaram Pradhan +5 more

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107146

N/A

0DataRank · unranked

8 citations

Christopher G. Goetz, Guanming Jiao, Raymundo Nuñez, Michael D. Olp, Alisha Dhiman +6 more

Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs)

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00944

N/A

0DataRank · unranked

8 citations

Matteo Pavan, Courtney Fisher, Veronica Salmaso, Tina C. Wan, Robert F. Keyes +8 more

Inhibition of Sirtuin Deacylase Activity by Peroxynitrite

Biochemistry(2024)10.1021/acs.biochem.4c00257

N/A

0DataRank · unranked

6 citations

Sarah L. Wynia‐Smith, Rachel A. Jones, Brian C. Smith, Kelsey S Bohl

Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108289

N/A

0DataRank · unranked

3 citations

Karina Bursch, Sarah L. Wynia‐Smith, Raymundo Nuñez, Christopher G. Goetz, Vaughn Jackson +2 more

ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces

BMC Bioinformatics(2020)10.1186/s12859-020-3513-y

N/A

0DataRank · unranked

55 citations

Kelsey Kalous, Brian C. Smith, Michael D. Olp

Polybromo-1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00352

N/A

0DataRank · unranked

0 citations

Karina Bursch, Savannah J. Makowski, Mingguang Xue, Kira Cozzolino, Shifali Shishodia +4 more

Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.9b01501

N/A

0DataRank · unranked

13 citations

Ayan Kumar Ghosh, Michael Forman, Xin Hu, Wenjuan Ye, Noel Southall +7 more

Development of activity-based probes for the protein deacylase Sirt1

Bioorganic Chemistry(2020)10.1016/j.bioorg.2020.104232

N/A

0DataRank · unranked

11 citations

Daniel J. Sprague, Brian C. Smith, Christopher J. Goetz