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Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.04.028Source: DataRank Database

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers is a research paper published in Computational and Structural Biotechnology Journal (2022). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.85)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Timothy J. Stodola ORCID,Thiago M. de Assuncao,Elise Leverence,Brian C. Smith ORCID,Brian F. Volkman ORCID

Live enrichment

PubMed:35615018 PMC:PMC9111933 OpenAlex:https://openalex.org/W4225009930

National Institutes of Health

Grant: R01DK052913

National Institutes of Health

Grant: R35GM128840

NCI NIH HHS

Grant: R01 CA247898

Medical College of Wisconsin

FWCI

1.85

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.csbj.2022.04.028

publisherhttps://doi.org/10.1016/j.csbj.2022.04.028

publisherhttps://api.elsevier.com/content/article/PII:S2001037022001453?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2001037022001453?httpAccept=text/plain

publisherhttps://spj.science.org/doi/pdf/10.1016/j.csbj.2022.04.028

Fields of Study

Genomics and Rare DiseasesEpigenetics and DNA MethylationGenomics and Phylogenetic Studies

Keywords

MutationComputational biologySomatic cellDemethylaseBiologyBioinformaticsGeneticsHistoneGeneCancerMolecular dynamicsgenomic variationhistone demethylaseprotein structureKabuki SyndromeMd, Molecular DynamicsPdb, Protein Data BankKdm6aRg, Radius Of GyrationSasa, Solvent-accessible Surface AreaSnp, Single Nucleotide PolymorphismRmsd, Root Mean Square DeviationTcga, The Cancer Genome AtlasHmt, Histone Methyltransferase2Og, 2-OxoglutarateTpr, Tetratricopeptide RepeatEpigenetic RegulatorHat, Hydrogen Atom TransferDv, Dynamics VariantsJmjc, Jumonji C DomainKdm6a, Histone Lysine(k)-specific Demethylase 6ASdv, Structural & Dynamics VariantsSv, Structural VariantsVus, Variant Of Uncertain (Unknown) SignificanceDbsnp, Single Nucleotide Polymorphism DatabaseCosmic, Catalog Of Somatic Mutations In CancerMutational Impact AnalysisRmsf, Root Mean Square FluctuationGnomad, Genome Aggregation Database

Sustainable Development Goals

SDG 0: Good health and well-being

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

FAIR Checklist

Authors (10)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)