Chaitan Khosla

MedicineBiochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 40 papers. Top paper: “KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19”.

KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

Science(2022)10.1126/science.abi9591

N/A

7.1DataRank · unranked

250 citations

Maxim Zaslavsky, Yapeng Su, Jing Guo, Michael J. Sikora, Vincent van Unen +31 more

Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial

Nature Communications(2021)10.1038/s41467-021-22177-1

N/A

3.5DataRank · unranked

149 citations

Jason R. Andrews, Hector Bonilla, Haley Hedlin, Karen B. Jacobson, Vidhya Balasubramanian +22 more

Mapping the catalytic conformations of an assembly-line polyketide synthase module

Science(2021)10.1126/science.abi8358

N/A

2.3DataRank · unranked

87 citations

Kaiming Zhang, Xiuyuan Li, Shanshan Li, Grigore Pintilie, Soung‐Hun Roh +4 more

Latiglutenase Protects the Mucosa and Attenuates Symptom Severity in Patients With Celiac Disease Exposed to a Gluten Challenge

Gastroenterology(2022)10.1053/j.gastro.2022.07.071

N/A

1.8DataRank · unranked

73 citations

Jack A. Syage, Tsung‐Teh Wu, Matthew A. Dickason, Ana G. Ramos, Carol Van Dyke +19 more

Structure and Mechanisms of Assembly-Line Polyketide Synthases

Annual Review of Biochemistry(2024)10.1146/annurev-biochem-080923-043654

N/A

0.805DataRank · unranked

32 citations

D.P. Cogan, Krystal L. Brodsky, Chaitan Khosla, Alexander M. Soohoo

Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study

eLife(2022)10.7554/elife.77943

N/A

0.769DataRank · unranked

19 citations

Kattria van der Ploeg, Saborni Chakraborty, Prabhu S. Arunachalam, Diego AM Mori, Karen B. Jacobson +22 more

Understanding Substrate Specificity of Polyketide Synthase Modules by Generating Hybrid Multimodular Synthases

Journal of Biological Chemistry(2003)10.1074/jbc.m305339200

N/A

0.648DataRank · unranked

74 citations

Clay C.C. Wang, Christopher N. Boddy, David E. Cane, Chaitan Khosla, Kenji Watanabe

Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism

Cell chemical biology(2020)10.1016/j.chembiol.2020.05.002

N/A

0.546DataRank · unranked

37 citations

Amita Gupta, Ayse Okesli-Armlovich, Wenjie Qiao, Curt R. Fischer, Mark Smith +4 more

Genomic mining and diversity of assembly line polyketide synthases

Open Biology(2023)10.1098/rsob.230096

N/A

0.506DataRank · unranked

12 citations

Chaitan Khosla, Shreya Kishore

GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2100751118

N/A

0.494DataRank · unranked

26 citations

Sur Herrera Paredes, Hunter B. Fraser, Chaitan Khosla, Aleksandra Nivina

Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102848

N/A

0.464DataRank · unranked

21 citations

Nina Fatuzzo, Nielson Weng, Wojciech Michno, Wentao Dong, Maryline Kienle +8 more

The COVID-19 Outpatient Pragmatic Platform Study (COPPS): Study design of a multi-center pragmatic platform trial

Contemporary Clinical Trials(2021)10.1016/j.cct.2021.106509

N/A

0.292DataRank · unranked

6 citations

Haley Hedlin, Natasha Purington, Vandana Sundaram, Kristopher Kapphahn, Yingjie Weng +12 more

Evaluation of Acebilustat, a Selective Inhibitor of Leukotriene B4 Biosynthesis, for Treatment of Outpatients With Mild-Moderate Coronavirus Disease 2019: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial

Clinical Infectious Diseases(2023)10.1093/cid/ciad187

N/A

0.269DataRank · unranked

5 citations

Haley Hedlin, Sophie Duong, Di Lu, Justin Lee, Bryan Bunning +15 more

Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.23.473930

N/A

0.165DataRank · unranked

2 citations

Maxim Zaslavsky, Yapeng Su, Michael J. Sikora, Vincent van Unen, Asbjørn Christophersen +27 more

Engineering site-selective incorporation of fluorine into polyketides

Nature Chemical Biology(2022)10.1038/s41589-022-01070-y

N/A

0DataRank · unranked

63 citations

Omer Ad, Thomas M. Privalsky, Swetha Ramesh, Joel L. Sax, Hongjun Dong +5 more

An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease

Nature Communications(2022)10.1038/s41467-022-28353-1

N/A

0DataRank · unranked

42 citations

Nielson Weng, Lichao Zhang, Andrew J. Hilmer, Lalla A. Fall, Kavya Swaminathan +6 more

In vivo visualization and molecular targeting of the cardiac conduction system

Journal of Clinical Investigation(2022)10.1172/jci156955

N/A

0DataRank · unranked

31 citations

Benjamin Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos +11 more

Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial

Research Square(2020)10.21203/rs.3.rs-110659/v1

N/A

0DataRank · unranked

7 citations

Jason R. Andrews, Hector Bonilla, Haley Hedlin, Karen B. Jacobson, Vidhya Balasubramanian +22 more

A Mouse Model of Celiac Disease

Current Protocols(2022)10.1002/cpz1.515

N/A

0DataRank · unranked

13 citations

Chaitan Khosla, Bana Jabrì, Valérie Abadie

Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP-1 Pathway

Journal of the American Chemical Society(2023)10.1021/jacs.3c05109

N/A

0DataRank · unranked

48 citations

Harrison A. Besser, Christina E. Lee, William Zhang, Bianxiao Cui, Chaitan Khosla +1 more

Celiac disease: mechanisms and emerging therapeutics

Trends in Pharmacological Sciences(2023)10.1016/j.tips.2023.09.006

N/A

0DataRank · unranked

42 citations

Chaitan Khosla, Harrison A. Besser

LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens

Cell chemical biology(2023)10.1016/j.chembiol.2022.12.002

N/A

0DataRank · unranked

17 citations

Harrison A. Besser, Agnele Sylvia Sewa, Fu-Chen Yang, Bana Jabrì, Chaitan Khosla +1 more

Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase

Biochemistry(2023)10.1021/acs.biochem.3c00156

N/A

0DataRank · unranked

5 citations

D.P. Cogan, Krystal L. Brodsky, Alexander M. Soohoo, Xiuyuan Li, Natalia Sevillano +5 more

Structural basis for intermodular communication in assembly-line polyketide biosynthesis

Nature Chemical Biology(2024)10.1038/s41589-024-01709-y

N/A

0DataRank · unranked

17 citations

Alexander M. Soohoo, Muyuan Chen, Yan Liu, Krystal L. Brodsky, Chaitan Khosla +1 more

Structural and mechanistic analysis of Ca 2+ -dependent regulation of transglutaminase 2 activity using a Ca 2+ -bound intermediate state

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2407066121

N/A

0DataRank · unranked

13 citations

Harrison A. Besser, Irimpan I. Mathews, Chaitan Khosla, Agnele Sylvia Sewa

Past, Present, and Future of Noninvasive Tests to Assess Gluten Exposure, Celiac Disease Activity, and End-Organ Damage

Gastroenterology(2024)10.1053/j.gastro.2024.01.053

N/A

0DataRank · unranked

9 citations

Luca Elli, Chaitan Khosla, Jason A. Tye-Din, Jocelyn A. Silvester

Enterocyte-Derived and Catalytically Active Transglutaminase 2 in the Gut Lumen of Mice: Implications for Celiac Disease

Gastroenterology(2024)10.1053/j.gastro.2024.05.029

N/A

0DataRank · unranked

9 citations

Liv Kleppa, Harrison A. Besser, Chaitan Khosla, M. Fleur du Pré, Ludvig M Sollid +1 more

Discovery and Characterization of the Fully Decorated Nocardiosis-Associated Polyketide Natural Product

Journal of the American Chemical Society(2024)10.1021/jacs.3c13670

N/A

0DataRank · unranked

7 citations

Antonio Del Rio Flores, Stephen R. Lynch, Kai P. Yuet, Chaitan Khosla, Shreya Kishore

New Insights into the Mechanism of Action of L-681,217, a Medicinally Promising Polyketide Inhibitor of Bacterial Protein Translation

Biochemistry(2024)10.1021/acs.biochem.4c00541

N/A

0DataRank · unranked

2 citations

Rolin A. Aguilar, Heewon Cho, Thomas M. Privalsky, Lin Liu, Khanh P. Nguyen +3 more

Characterization of the Flavin-Dependent Monooxygenase Involved in the Biosynthesis of the Nocardiosis-Associated Polyketide

Biochemistry(2024)10.1021/acs.biochem.4c00480

N/A

0DataRank · unranked

3 citations

Chaitan Khosla, Antonio Del Rio Flores

Peyer’s Patch B Cells Sample Transglutaminase-Gluten Complexes and Drive Celiac Disease Autoimmunity

Gastroenterology(2025)10.1053/j.gastro.2025.06.021

N/A

0DataRank · unranked

6 citations

Liv Kleppa, Alisa E. Dewan, Maureen Tania Meling, Lene S. Høydahl, Harrison A. Besser +3 more

ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer’s Disease Pathogenesis

Biochemistry(2025)10.1021/acs.biochem.5c00503

N/A

0DataRank · unranked

2 citations

Dylan Reil, Nina Fatuzzo, Ming Fu, Yuxing Dai, D. Martínez +5 more

A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.02.657527

N/A

0DataRank · unranked

0 citations

Harrison A. Besser, Hye Rin Chun, Megan A. Albertelli, Nielsen Fernandez‐Becker, Bana Jabrì +2 more

Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction

Journal of the American Chemical Society(2020)10.1021/jacs.0c05133

N/A

0DataRank · unranked

11 citations

Xiuyuan Li, Natalia Sevillano, Irimpan I. Mathews, Tsutomu Matsui, Charles S. Craik +2 more

Fragment antigen binding domains (Fabs) as tools to study assembly-line polyketide synthases

Synthetic and Systems Biotechnology(2021)10.1016/j.synbio.2021.12.003

N/A

0DataRank · unranked

3 citations

Chaitan Khosla, Katarina M. Guzman

An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.17.435829

N/A

0DataRank · unranked

2 citations

Nielson Weng, Lichao Zhang, Andrew J. Hilmer, Lalla A. Fall, Kavya Swaminathan +6 more

Analysis of a “Split-and-Stuttering” Module of an Assembly Line Polyketide Synthase

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.15.426894

N/A

0DataRank · unranked

0 citations

Kai P. Yuet, Stephen R. Lynch, Corey W. Liu, Chaitan Khosla, Katarina M. Guzman

SARS-CoV-2 subgenomic RNA kinetics in longitudinal clinical samples

medRxiv(2021)10.1101/2021.04.26.21256131

N/A

0DataRank · unranked

0 citations

Eugene Kim, Giovanny J. Martínez-Colón, Prasanna Jagannathan, Arjun Rustagi, Julie Parsonnet +9 more

SARS-CoV-2 Subgenomic RNA Kinetics in Longitudinal Clinical Samples

Open Forum Infectious Diseases(2021)10.1093/ofid/ofab310

N/A

0DataRank · unranked

33 citations

Eugene Kim, Giovanny J. Martínez-Colón, Prasanna Jagannathan, Arjun Rustagi, Julie Parsonnet +9 more

Complete Reconstitution and Deorphanization of the 3 MDa NOCAP (NOCardiosis-Associated Polyketide) Synthase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.28.923383

N/A

0DataRank · unranked

0 citations

Corey W. Liu, Stephen R. Lynch, James Kuo, Wesley Michaels, Robert Lee +5 more