Amit V. Khera

Also affiliated with Harvard University, Verve Therapeutics (United States)

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

10.2Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Papers

Driven by 48 papers — median percentile 72. Top paper: “Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants”.

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Nature Genetics(2022)10.1038/s41588-022-01233-6

N/A

7.7DataRank · unranked

721 citations

Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N. Wolford, Deepak Atri +92 more

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

Nature Genetics(2022)10.1038/s41588-022-01036-9

N/A

6.6DataRank · unranked

284 citations

Masahiro Kanai, Huwenbo Shi, Steven Gazal, Wouter J. Peyrot, Amit V. Khera +30 more

Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

Nature Medicine(2024)10.1038/s41591-024-02796-z

N/A

4.8DataRank · unranked

196 citations

Leah C. Kottyan, Christopher Kachulis, Noura S. Abul‐Husn, Joshua Arias, Gillian M. Belbin +73 more

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

Nature Communications(2018)10.1038/s41467-018-03911-8

N/A

3.1DataRank · unranked

104 citations

Amit V. Khera, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Krishna Aragam +43 more

An open resource of structural variation for medical and population genetics

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/578674

Top 9%

2.2DataRank

Top 9%44 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +37 more

Selection of 51 predictors from 13,782 candidate multimodal features using machine learning improves coronary artery disease prediction

Patterns(2021)10.1016/j.patter.2021.100364

N/A

2.1DataRank · unranked

43 citations

Marcus D. R. Klarqvist, Connor A. Emdin, Aniruddh P. Patel, Manish Paranjpe, Patrick T. Ellinor +5 more

A single cell atlas of human and mouse white adipose tissue

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.09.466968

N/A

2.0DataRank · unranked

57 citations

Christopher Jacobs, Adam L. Essene, Deepti Pant, Danielle Tenen, Georgia Colleluori +38 more

Titin Truncating Variants in Adults Without Known Congestive Heart Failure

Journal of the American College of Cardiology(2020)10.1016/j.jacc.2020.01.013

N/A

1.6DataRank · unranked

28 citations

Alexander G. Bick, Mark Chaffin, Krishna G. Aragam, Seung Hoan Choi, Steven A. Lubitz +7 more

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Cell(2019)10.1016/j.cell.2019.03.028

N/A

1.0DataRank · unranked

842 citations

Mark Chaffin, Kaitlin H. Wade, Sohail Zahid, Joseph Brancale, Rui Xia +14 more

The PRIMED Consortium: Reducing disparities in polygenic risk assessment

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.10.010

N/A

0.893DataRank · unranked

37 citations

Matthew P. Conomos, Sarah C. Nelson, Sally N. Adebamowo, Ananyo Choudhury, David V. Conti +90 more

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

Nature Communications(2020)10.1038/s41467-020-15823-7

N/A

0.843DataRank · unranked

275 citations

Alexander G. Bick, Minxian Wang, Mark Chaffin, Sam Friedman, Jie Yao +14 more

Machine learning enables new insights into clinical significance of and genetic contributions to liver fat accumulation

medRxiv(2020)10.1101/2020.09.03.20187195

N/A

0.821DataRank · unranked

15 citations

James P. Pirruccello, Sam Friedman, Connor A. Emdin, Veeral Ajmera, Tracey G. Simon +11 more

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Nature Genetics(2022)10.1038/s41588-022-01078-z

N/A

0.793DataRank · unranked

197 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +86 more

Prediction performance and fairness heterogeneity in cardiovascular risk models

Scientific Reports(2022)10.1038/s41598-022-16615-3

N/A

0.764DataRank · unranked

23 citations

Shaan Khurshid, Bum Chul Kwon, Aniruddh P. Patel, Puneet Batra, Anthony Philippakis +5 more

Association of machine learning-derived measures of body fat distribution with cardiometabolic diseases in >40,000 individuals

medRxiv(2021)10.1101/2021.05.07.21256854

Top 28%

0.704DataRank

Top 28%17 citations

Marcus D. R. Klarqvist, Nathaniel Diamant, Takara L. Stanley, Patrick T. Ellinor, Nehal N. Mehta +7 more

Machine learning enables new insights into genetic contributions to liver fat accumulation

Cell Genomics(2021)10.1016/j.xgen.2021.100066

N/A

0.700DataRank · unranked

105 citations

James P. Pirruccello, Sam Friedman, Minxian Wang, Connor A. Emdin, Veeral Ajmera +12 more

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

medRxiv(2021)10.1101/2021.05.24.21257377

N/A

0.637DataRank · unranked

69 citations

Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N. Wolford, Elle M. Weeks +87 more

Author Correction: A single-cell atlas of human and mouse white adipose tissue

Nature(2023)10.1038/s41586-023-06445-2

Top 34%

0.569DataRank

Top 34%13 citations

Christopher Jacobs, Adam L. Essene, Deepti Pant, Danielle Tenen, Georgia Colleluori +38 more

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

medRxiv(2021)10.1101/2020.12.26.20248491

N/A

0.425DataRank · unranked

16 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +85 more

Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations

medRxiv(2023)10.1101/2023.05.25.23290535

N/A

0.330DataRank · unranked

8 citations

Leah C. Kottyan, Christopher Kachulis, Noura S. Abul‐Husn, Josh Arias, Gillian M. Belbin +71 more

Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease

PLoS Genetics(2022)10.1371/journal.pgen.1010294

N/A

0.292DataRank · unranked

6 citations

Mark Chaffin, Sohail Zahid, Scott C. Ritchie, Jerome I. Rotter, Stephen S. Rich +11 more

Rare penetrant mutations confer severe risk of common diseases

medRxiv(2023)10.1101/2023.05.01.23289356

N/A

0.269DataRank · unranked

5 citations

Jeremy F. McRae, Jacob C. Ulirsch, Jacqueline S. Dron, Tobias Hamp, Yanshen Yang +16 more

Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.12.946038

N/A

0.240DataRank · unranked

3 citations

Alexander G. Bick, Minxian Wang, Mark Chaffin, Steven A. Lubitz, Patrick T. Ellinor +4 more

Opportunistic hepatic steatosis assessment in low-dose coronary artery calcium CT using liver adipose-radiomic index (LARI)

EBioMedicine(2025)10.1016/j.ebiom.2025.105982

N/A

0.165DataRank · unranked

2 citations

Rohan Dhamdhere, Sanjay Rajagopalan, Jonathan R. Walker, Amit V. Khera, James A. de Lemos +7 more

Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of multiple cardiovascular disease risk factors

medRxiv(2022)10.1101/2022.03.29.22273133

N/A

0.111DataRank · unranked

1 citations

B Kavitha, Siqi Hu, Roi Isaac, Minxian Wang, Xiaomi Du +16 more

Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities

Cell Metabolism(2024)10.1016/j.cmet.2024.06.004

N/A

0DataRank · unranked

109 citations

Injeong Shim, Akl C. Fahed, Ron Do, Woong-Yang Park, Pradeep Natarajan +3 more

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

PLoS Genetics(2020)10.1371/journal.pgen.1008629

N/A

0DataRank · unranked

169 citations

Mary E. Haas, Amit V. Khera, Krishna G. Aragam, Mark Chaffin, Derek Klarin +37 more

Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank

International Journal for Equity in Health(2020)10.1186/s12939-020-01227-y

N/A

0DataRank · unranked

147 citations

Manish Paranjpe, Nina P. Kathiresan, Manuel A. Rivas, Amit V. Khera, Aniruddh P. Patel

Improving reporting standards for polygenic scores in risk prediction studies

medRxiv(2020)10.1101/2020.04.23.20077099

N/A

0DataRank · unranked

55 citations

Samuel A. Lambert, Cecelia P. Tamburro, Michael A. Iacocca, Jack W. O’Sullivan, Catherine H. Sillari +28 more

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

Apollo (University of Cambridge)(2020)10.17863/cam.52580

N/A

0DataRank · unranked

0 citations

Mary E. Haas, Amit V. Khera, Krishna G. Aragam, Mark Chaffin, Derek Klarin +37 more

Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100437

N/A

0DataRank · unranked

256 citations

Erik Abner, Connor A. Emdin, Émilie Gobeil, Nele Taba, Mary E. Haas +15 more

Coronary Artery Calcium for the Allocation of GLP-1RA for Primary Prevention of Atherosclerotic Cardiovascular Disease

JACC. Cardiovascular imaging(2021)10.1016/j.jcmg.2020.12.024

N/A

0DataRank · unranked

34 citations

Kershaw V. Patel, Renato Quispe, Parag H. Joshi, Amit V. Khera, Colby Ayers +10 more

Leveraging fine-mapping and non-European training data to improve cross-population polygenic risk scores

medRxiv(2021)10.1101/2021.01.19.21249483

N/A

0DataRank · unranked

31 citations

Masahiro Kanai, Huwenbo Shi, Steven Gazal, Wouter J. Peyrot, Amit V. Khera +6 more

A framework for integrated clinical risk assessment using population sequencing data

medRxiv(2021)10.1101/2021.08.12.21261563

N/A

0DataRank · unranked

6 citations

Tho Tran, Jackson R. Bernatchez, Keithen E. Shepard, Christopher Koch, Aniruddh P. Patel +10 more

Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study

medRxiv(2021)10.1101/2021.11.19.21266578

N/A

0DataRank · unranked

6 citations

Minku Song, Soyeon Kim, Beomsu Kim, Wonseok Kang, Jong Yeob Kim +6 more

Characterizing and Quantifying Performance Heterogeneity in Cardiovascular Risk Prediction Models — A Step Towards Improved Disease Risk Assessment

Research Square(2021)10.21203/rs.3.rs-936366/v1

N/A

0DataRank · unranked

1 citations

Shaan Khurshid, Bum Chul Kwon, Aniruddh P. Patel, Puneet Batra, Anthony Philippakis +5 more

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

medRxiv(2021)10.1101/2021.10.21.21264378

N/A

0DataRank · unranked

0 citations

John Dominy, Shareef Khalid, Linh Vong, Shari L. Caplan, Treeve Currie +22 more

Electronic Health Record-Based Genome-Wide Meta-Analysis and Mendelian Randomization Identify Metabolic and Phenotypic Consequences of Non-Alcoholic Fatty Liver Disease

Research Square(2021)10.21203/rs.3.rs-97977/v2

N/A

0DataRank · unranked

0 citations

Erik Abner, Connor A. Emdin, Émilie Gobeil, Nele Taba, Mary J. Haas +16 more

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

PLoS Genetics(2022)10.1371/journal.pgen.1010093

N/A

0DataRank · unranked

3 citations

John Dominy, Shareef Khalid, Linh Vong, Shari L. Caplan, Treeve Currie +21 more

Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study

Obesity(2023)10.1002/oby.23722

N/A

0DataRank · unranked

34 citations

Minku Song, Soyeon Kim, Beomsu Kim, Wonseok Kang, Jong Yeob Kim +6 more

Clinical utility of polygenic scores for cardiometabolic disease in Arabs

Nature Communications(2023)10.1038/s41467-023-41985-1

N/A

0DataRank · unranked

22 citations

Hiroyuki Kuwahara, Ningning Chen, Mais O. Hashem, Lama AlAbdi, Mohamed Abouelhoda +8 more

Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research

Circulation Genomic and Precision Medicine(2023)10.1161/circgen.123.004181

N/A

0DataRank · unranked

26 citations

Carolina Roselli, MacKenzie Brandes, Marc Duby, Quy Hoang, Dongkeun Jang +17 more

Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins

Cell Genomics(2023)10.1016/j.xgen.2023.100339

N/A

0DataRank · unranked

20 citations

B Kavitha, Siqi Hu, Roi Isaac, Lynne Krohn, Minxian Wang +17 more

Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease

Circulation(2023)10.1161/circulationaha.123.064168

N/A

0DataRank · unranked

12 citations

Jacqueline S. Dron, Brandon K. Bellows, Amit V. Khera, Junxiu Liu, Pallavi Balte +27 more

Mapping and characterization of structural variation in 17,795 human genomes

UNC Libraries(2024)10.17615/bjv3-ys88

Top 100%

0DataRank

Top 100%0 citations

S.S. Rich, Elizabeth L. Appelbaum, Ryan M. Layer, Subra Kugathasan, Scott M. Damrauer +95 more

The PRIMED Consortium: Reducing disparities in polygenic risk assessment

UNC Libraries(2024)10.17615/67cq-h633

N/A

0DataRank · unranked

0 citations

John S. Witte, Iman K. Martin, Sally N. Adebamowo, Maggie C. Y. Ng, Eimear E. Kenny +22 more

Lifestyle Interventions in Cardiovascular-Kidney-Metabolic Syndrome JACC: Advances Expert Panel

JACC Advances(2025)10.1016/j.jacadv.2025.101788

N/A

0DataRank · unranked

11 citations

Jerrin Philip, Eleonora Avenatti, Deepika Laddu, Michael D Shapiro, Amit V. Khera +6 more

Amit V. Khera

Indexed papers

Top data-sharing exemplar

Papers