Timothy A. Springer

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2”.

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

eLife(2021)10.7554/elife.74707

N/A

0.679DataRank · unranked

13 citations

Xianchi Dong, Adam DeCosta, Yang Su, Fiona Angrisano, Katarzyna A Sala +4 more

Ligand binding initiates single-molecule integrin conformational activation

Cell(2024)10.1016/j.cell.2024.04.049

N/A

0.628DataRank · unranked

65 citations

Myung Hyun Jo, Jiabin Yan, Taylor Hall, Joon Lee, Uriel López-Sánchez +4 more

Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102323

N/A

0.515DataRank · unranked

30 citations

Roxana E. Iacob, Jing Li, John R. Engen, Timothy A. Springer, Yang Su

Single-molecule imaging of von Willebrand factor reveals tension-dependent self-association

Blood(2021)10.1182/blood.2021012595

N/A

0.434DataRank · unranked

17 citations

Yan Jiang, Wesley P. Wong, Timothy A. Springer, Hongxia Fu

Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state

Nature Communications(2022)10.1038/s41467-022-31744-z

N/A

0.312DataRank · unranked

7 citations

Xianchi Dong, Yang Su, Chafen Lu, Timothy A. Springer, Juan Feng

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465389

N/A

0DataRank · unranked

0 citations

Xianchi Dong, Adam DeCosta, Yang Su, Fiona Angrisano, Katarzyna Sala +4 more

Single-molecule characterization of subtype-specific β1 integrin mechanics

Nature Communications(2022)10.1038/s41467-022-35173-w

N/A

0DataRank · unranked

48 citations

Jing Li, Valentin Jaumouillé, Yuxin Hao, Jessica Coppola, Jiabin Yan +4 more

Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange

Blood(2022)10.1182/blood.2022016467

N/A

0DataRank · unranked

27 citations

Jing Li, Timothy A. Springer, Alan Brown, Jacob R. Anderson

Loss of LRRC33-Dependent TGFβ1 Activation Enhances Antitumor Immunity and Checkpoint Blockade Therapy

Cancer Immunology Research(2022)10.1158/2326-6066.cir-21-0593

N/A

0DataRank · unranked

19 citations

Qin Yan, Timothy A. Springer, Aiping Jiang

Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker

eLife(2022)10.7554/elife.75760

N/A

0DataRank · unranked

13 citations

Roxana E. Iacob, Nathan E. Hudson, Jing Li, Chafen Lu, John R. Engen +2 more

Protection of the Prodomain α1-Helix Correlates with Latency in the Transforming Growth Factor-β Family

Journal of Molecular Biology(2022)10.1016/j.jmb.2021.167439

N/A

0DataRank · unranked

9 citations

Roxana E. Iacob, Bo Zhao, Yang Su, Yuan Tian, Cameron Toohey +3 more

Von Willebrand factor A1 domain affinity for GPIbα and stability are differentially regulated by its O-glycosylated N-linker and C-linker

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.13.476208

N/A

0DataRank · unranked

0 citations

Roxana E. Iacob, Nathan E. Hudson, Jing Li, Chafen Lu, John R. Engen +2 more

Subtype-specific single β1 integrin mechanics for activation, mechanotransduction and cytoskeleton remodeling

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.08.495291

N/A

0DataRank · unranked

0 citations

Jing Li, Valentin Jaumouillé, Yuxin Hao, Jessica Coppola, Jiabin Yan +4 more

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

Nature Communications(2023)10.1038/s41467-023-41272-z

N/A

0DataRank · unranked

48 citations

Lei Shi, Ashley Chang, Xianchi Dong, Andres Fernandez, John C. Kraft +35 more

Conformational change of Plasmodium TRAP is essential for sporozoite migration and transmission

EMBO Reports(2023)10.15252/embr.202357064

N/A

0DataRank · unranked

17 citations

Dennis Klug, Jessica Kehrer, Gaojie Song, Juan Feng, Timothy A. Springer +2 more

A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104901

N/A

0DataRank · unranked

11 citations

Elizabeth H. Konopka, Woojin Kim, Yuki Taga, Kazunori Mizuno, Timothy A. Springer +4 more

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.12.544624

N/A

0DataRank · unranked

2 citations

Lei Shi, Ashley Chang, Xianchi Dong, Andres Fernandez, John C. Kraft +35 more

Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits

mAbs(2024)10.1080/19420862.2024.2365891

N/A

0DataRank · unranked

6 citations

Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Roushu Zhang +7 more

De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.21.600123

N/A

0DataRank · unranked

2 citations

Jordi Guillem‐Marti, Saurav Kumar, David Lee, Daniel Cabrerizo‐Aguado, R. Werther +21 more

Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.26.577394

N/A

0DataRank · unranked

1 citations

Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Roushu Zhang +7 more

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials(2025)10.1002/adma.202500872

N/A

0DataRank · unranked

7 citations

Jordi Guillem‐Marti, Saurav Kumar, David Lee, Daniel Cabrerizo‐Aguado, R. Werther +21 more

Design and assessment of TRAP-CSP fusion antigens as effective malaria vaccines

PLoS ONE(2020)10.1371/journal.pone.0216260

N/A

0DataRank · unranked

22 citations

Gaojie Song, Kristin Beale, Jiabin Yan, Emma Garst, Juan Feng +4 more

Nanobodies targeting EGFR provide insight into conformations stabilized by glioblastoma mutations

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110374

N/A

0DataRank · unranked

7 citations

Edward P. Harvey, Novalia Pishesha, Hidde L. Ploegh, Timothy A. Springer, Sean Watson

Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP

eLife(2020)10.7554/elife.57572

N/A

0DataRank · unranked

30 citations

Sarah Goellner, Jessica Kehrer, Julia M. Sattler, Léanne Strauss, Mirko Singer +4 more

Congenital X‐linked neutropenia with myelodysplasia and somatic tetraploidy due to a germline mutation in SEPT6

American Journal of Hematology(2021)10.1002/ajh.26382

N/A

0DataRank · unranked

8 citations

Katelyn E. Gagne, Ellen M. Beauchamp, Jonathan Fogel, Aleksej Perlov, Mireia Sola +17 more

Protection of the prodomain α1-helix correlates with latency in the transforming growth factor-β family

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.24.449816

N/A

0DataRank · unranked

0 citations

Bo Zhao, Roxana E. Iacob, Yuan Tian, Cameron Toohey, John R. Engen +2 more

Low affinity integrin states have faster binding kinetics than the high affinity state

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.26.453735

N/A

0DataRank · unranked

0 citations

Jiabin Yan, Timothy A. Springer, Jing Li