Gustav Akk

Also affiliated with Mallinckrodt (United States), Innovative Research (United States)

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI”.

Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101455

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0.345DataRank · unranked

9 citations

Kemburli Munoz, Eloisa Peredia, Gustav Akk, Ayman K. Hamouda, Farah Deba

Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions

Molecular Pharmacology(2020)10.1124/molpharm.120.000066

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0DataRank · unranked

12 citations

Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach +1 more

Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites

Molecular Pharmacology(2020)10.1124/mol.120.119842

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0DataRank · unranked

5 citations

David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach +2 more

Reduced Activation of the Synaptic-Type GABAA Receptor Following Prolonged Exposure to Low Concentrations of Agonists: Relationship between Tonic Activity and Desensitization

Molecular Pharmacology(2020)10.1124/molpharm.120.000088

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0DataRank · unranked

5 citations

Allison L. Germann, Alex S. Evers, Joe Henry Steinbach, Gustav Akk, Spencer R. Pierce

Site-specific effects of neurosteroids on GABA A receptor activation and desensitization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.063404

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0DataRank · unranked

1 citations

Wayland W.L. Cheng, John Bracamontes, Zi-Wei Chen, Lei Wang, Allison L. Germann +8 more

Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAAReceptor: Relating Occupancy to State Functions

Molecular Pharmacology(2020)10.1124/mol.120.000066

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0DataRank · unranked

0 citations

Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach +1 more

Intrasubunit and Intersubunit Steroid Binding Sites Independently and Additively Mediate α1β2γ2L GABAA Receptor Potentiation by the Endogenous Neurosteroid Allopregnanolone

Molecular Pharmacology(2021)10.1124/molpharm.121.000268

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0DataRank · unranked

23 citations

Spencer R. Pierce, Hiroki Tateiwa, Yusuke Sugasawa, David E. Reichert, Alex S. Evers +3 more

Activation of the α1β2γ2L GABAA Receptor by Physiological Agonists

Biomolecules(2021)10.3390/biom11121864

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2 citations

Allison L. Germann, Gustav Akk, Spencer R. Pierce

(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop

Biochemical Pharmacology(2022)10.1016/j.bcp.2022.114993

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0DataRank · unranked

6 citations

Cecilia M. Borghese, Allison L. Germann, Spencer R. Pierce, Alessandro Bonardi, Alessio Nocentini +6 more

Potentiation of the GABAAR reveals variable energetic contributions by etiocholanolone and propofol

Biophysical Journal(2023)10.1016/j.bpj.2023.09.014

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0DataRank · unranked

7 citations

Sophia Q. Xu, Allison L. Germann, Joe Henry Steinbach, Gustav Akk, Spencer R. Pierce

UNC-49 is a redox-sensitive GABA A receptor that regulates the mitochondrial unfolded protein response cell nonautonomously

Science Advances(2023)10.1126/sciadv.adh2584

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8 citations

Allison L. Germann, Jack Mao, Sydney Hou, Bayode Bakare, Paul Kong Thoo Lin +6 more

Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABAA Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor

Biomolecules(2023)10.3390/biom13040698

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2 citations

Allison L. Germann, Sophia Q. Xu, Saumith L. Menon, Marcelo O. Ortells, Hugo R. Arias +2 more

Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor

Molecular Pharmacology(2023)10.1124/molpharm.123.000692

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0DataRank · unranked

2 citations

Spencer R. Pierce, Allison L. Germann, Sophia Q. Xu, Marcelo O. Ortells, Seiji Sakamoto +5 more

Three classes of propofol binding sites on GABAA receptors

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107778

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0DataRank · unranked

12 citations

Satyanarayana M. Chintala, John Bracamontes, Yusuke Sugasawa, Spencer R. Pierce, Balázs R. Varga +7 more

Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channel

Biochemical Pharmacology(2024)10.1016/j.bcp.2024.116183

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0DataRank · unranked

9 citations

Marcelo O. Ortells, Arsalan Yousuf, Sophia Q. Xu, Gustav Akk, David J. Adams +2 more

Inhibitory Actions of Potentiating Neuroactive Steroids in the Human α1β3γ2L γ-Aminobutyric Acid Type A Receptor

Molecular Pharmacology(2024)10.1124/molpharm.124.000960

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0DataRank · unranked

4 citations

Allison L. Germann, Douglas F. Covey, Alex S. Evers, Joe Henry Steinbach, Gustav Akk +1 more

Direct measurements of neurosteroid binding to specific sites on GABAA receptors

British Journal of Pharmacology(2024)10.1111/bph.16490

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0DataRank · unranked

5 citations

Hiroki Tateiwa, Mingxing Qian, Yuanjian Xu, Fatima Amtashar, Ziwei Chen +7 more

Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00571

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0DataRank · unranked

2 citations

Peter Reinholdt, Rasmus Schnoor-Madsen, Line Lauritsen, J P Bader, M. Qian +9 more

Comparison of Behavioral Effects of GABAergic Low- and High-Efficacy Neuroactive Steroids in the Zebrafish Larvae Assay

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.3c00836

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0DataRank · unranked

1 citations

Yuanjian Xu, Douglas F. Covey, Alex S. Evers, Gustav Akk, Allison L. Germann

Site-specific effects of neurosteroids on GABAA receptor activation and desensitization

eLife(2020)10.7554/elife.55331

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0DataRank · unranked

60 citations

Wayland W.L. Cheng, John Bracamontes, Zi-Wei Chen, Lei Wang, Allison L. Germann +8 more

Null method to estimate the maximal PA at subsaturating concentrations of agonist

The Journal of General Physiology(2024)10.1085/jgp.202413644

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0DataRank · unranked

0 citations

Steven R. Pierce, Joe Henry Steinbach, Gustav Akk, Allison L. Germann