Willard M. Freeman

Also affiliated with Oklahoma Medical Research Foundation, Oklahoma City VA Medical Center, University of Oklahoma Health Sciences Center

NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 48 papers. Top paper: “Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia”.

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Communications Biology(2020)10.1038/s42003-020-01418-x

N/A

0.845DataRank · unranked

47 citations

Sarah R. Ocañas, David R. Stanford, Victor A. Ansere, Kyla B. Buettner, Hunter L. Porter +9 more

VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction

Nature Communications(2024)10.1038/s41467-024-53891-1

N/A

0.507DataRank · unranked

14 citations

Kelsey A Carter, Kevin D. Pham, Nina T. Cassidy, A Markiewicz, Michael I. Thellmann +4 more

Chromosomal and gonadal factors regulate microglial sex effects in the aging brain

Brain Research Bulletin(2023)10.1016/j.brainresbull.2023.02.008

N/A

0.483DataRank · unranked

24 citations

Victor A. Ansere, Collyn M. Kellogg, José V.V. Isola, Ana J. Chucair‐Elliott, Willard M. Freeman +1 more

Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.07.531435

N/A

0.416DataRank · unranked

15 citations

Kevin D. Pham, Adeline H. Machalinski, Hunter L. Porter, Harris E. Blankenship, Kyla B. Tooley +8 more

Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques

GeroScience(2023)10.1007/s11357-023-00767-9

N/A

0.373DataRank · unranked

11 citations

Kelli L. Vaughan, José V.V. Isola, Shivani N. Mann, Bayli Wellman, Jessica M. Hoffman +4 more

A satellite cell‐dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity

The FASEB Journal(2025)10.1096/fj.202500177r

N/A

0.345DataRank · unranked

9 citations

Davis A. Englund, Toby L. Chambers, Cory M. Dungan, Hunter L. Porter, Jonathan D. Wren +4 more

A single-cell atlas of the aging murine ovary

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.29.538828

N/A

0.292DataRank · unranked

6 citations

Sarah R. Ocañas, Chase R. Hubbart, Sung-Hwan Ko, Samim Ali Mondal, Jéssica D. Hense +7 more

Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age

iScience(2023)10.1016/j.isci.2023.108413

N/A

0.241DataRank · unranked

4 citations

Kevin D. Pham, Sung-Hwan Ko, Jillian E. J. Cox, Adeline H. Machalinski, Michael B. Stout +6 more

Late-Life Short-Term Dietary Restriction Improves Intestinal Stem Cell Function and Alters Intestinal Stem Cell Deoxyribonucleic Acid Methylation in Mice

Journal of Nutrition(2025)10.1016/j.tjnut.2025.05.044

N/A

0.208DataRank · unranked

3 citations

Michael D. Chan, Eric J. Moore, Michelle Ranjo‐Bishop, Kevin D. Pham, David R. Stanford +3 more

Protocol to sequentially isolate mouse oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons via magnetic cell sorting

STAR Protocols(2025)10.1016/j.xpro.2025.104139

N/A

0.208DataRank · unranked

3 citations

Dominika Siodłak, Kevin D. Pham, Casandra Salinas-Salinas, Sarah R. Ocañas, Willard M. Freeman +2 more

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome

Journal of Visualized Experiments(2023)10.3791/64765

N/A

0.165DataRank · unranked

2 citations

José V. V. Isola, Tatiana D. Saccon, Kevin D. Pham, Ana J. Chucair‐Elliott, Augusto Schneider +3 more

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.02.130674

N/A

0.165DataRank · unranked

2 citations

Niran Hadad, Molly Nelson-Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal +8 more

Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosis

GeroScience(2025)10.1007/s11357-025-01994-y

N/A

0.104DataRank · unranked

1 citations

Sunho Lee, M. Saminathan, Puvarajan Boovalingam, Kavitha Kurup, Kevin Pham +5 more

Hypothalamic melanocortin-4 receptors on astrocytes mediate inflammation and body weight homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.01.518727

N/A

0DataRank · unranked

0 citations

Kevin Pham, Rohan Varshney, Jacob W. Farriester, Charles I. Lacy, Heather C. Rice +4 more

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Journal of Neuroinflammation(2023)10.1186/s12974-023-02870-2

N/A

0DataRank · unranked

73 citations

Kevin D. Pham, Jillian E. J. Cox, Alex W. Keck, Sung-Hwan Ko, Felix A. Ampadu +10 more

Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans

GeroScience(2023)10.1007/s11357-023-00859-6

N/A

0DataRank · unranked

39 citations

Kevin D. Pham, Adeline H. Machalinski, Hunter L. Porter, Harris E. Blankenship, Kyla B. Tooley +8 more

Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis

Molecular Cancer Research(2023)10.1158/1541-7786.mcr-22-0820

N/A

0DataRank · unranked

26 citations

Nidheesh Thadathil, Phoebe Ohene-Marfo, Albert L. Tran, Michael Van Der Veldt, Constantin Georgescu +11 more

Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases

GeroScience(2023)10.1007/s11357-023-00955-7

N/A

0DataRank · unranked

14 citations

Hoang Van M. Nguyen, Nidheesh Thadathil, Roman F. Wolf, Willard M. Freeman, Christopher D. Wiley +3 more

Differential usage of DNA modifications in neurons, astrocytes, and microglia

Epigenetics & Chromatin(2023)10.1186/s13072-023-00522-6

N/A

0DataRank · unranked

10 citations

Ana J. Chucair‐Elliott, Sarah R. Ocañas, Adeline H. Machalinski, Kevin D. Pham, Walker Hoolehan +4 more

Heterochronic Plasma Transfer: Experimental Design, Considerations, and Technical Challenges

Rejuvenation Research(2023)10.1089/rej.2023.0035

N/A

0DataRank · unranked

3 citations

Matthew P. Bubak, Benjamin F. Miller, Willard M. Freeman, Victor A. Ansere

Methylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.20.572465

N/A

0DataRank · unranked

2 citations

Victor A. Ansere, Ram Babu Undi, Walker Hoolehan, Cory B. Giles, Chase A. Brown +5 more

Data from Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis

(2023)10.1158/1541-7786.c.6695932

N/A

0DataRank · unranked

0 citations

Nidheesh Thadathil, Phoebe Ohene-Marfo, Albert L. Tran, Michael Van Der Veldt, Constantin Georgescu +11 more

Consistent specificity and efficiency of tamoxifen-mediated cre induction across ages

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.19.558482

N/A

0DataRank · unranked

0 citations

Kevin D. Pham, Sung-Hwan Ko, Jillian E. J. Cox, Adeline H. Machalinski, Michael B. Stout +6 more

VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.16.567486

N/A

0DataRank · unranked

0 citations

Kelsey A Carter, Nina T. Cassidy, A Markiewicz, Michael I. Thellmann, Amanda L. Sharpe +3 more

A single-cell atlas of the aging mouse ovary

Nature Aging(2024)10.1038/s43587-023-00552-5

N/A

0DataRank · unranked

176 citations

Sarah R. Ocañas, Chase R. Hubbart, Sung-Hwan Ko, Samim Ali Mondal, Jéssica D. Hense +7 more

Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging

Journal of Neuroinflammation(2024)10.1186/s12974-024-03130-7

N/A

0DataRank · unranked

52 citations

Emily Ko, Amelia E. Andrews, Juliana Shin, Karina Nance, Pijus Barman +5 more

Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium

Neurobiology of Aging(2024)10.1016/j.neurobiolaging.2024.04.012

N/A

0DataRank · unranked

12 citations

Sarah R. Ocañas, Kevin D. Pham, Adeline H. Machalinski, Scott M. Plafker, Michael B. Stout +3 more

Transcriptomic Analysis Reveals That Excessive Thyroid Hormone Signaling Impairs Phototransduction and Mitochondrial Bioenergetics and Induces Cellular Stress in Mouse Cone Photoreceptors

International Journal of Molecular Sciences(2024)10.3390/ijms25137435

N/A

0DataRank · unranked

3 citations

David R. Stanford, Willard M. Freeman, Xi-Qin Ding, Hongwei Ma

Comparative analysis of In vivo endothelial cell translatomes across central nervous system vascular beds

Experimental Eye Research(2024)10.1016/j.exer.2024.110101

N/A

0DataRank · unranked

3 citations

Kevin D. Pham, Audrey Cleuren, Christopher M. Schafer, Courtney T. Griffin, Sarah R. Ocañas +3 more

Changes in microglia chromatin accessibility in aged female mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.18.575944

N/A

0DataRank · unranked

0 citations

Kyla B. Tooley, Kottapalli Srividya, Walker Hoolehan, Kevin D. Pham, Sarah R. Ocañas +2 more

P-glycoprotein expression skews mitochondrial dye measurements in T cells

Frontiers in Immunology(2025)10.3389/fimmu.2025.1560104

N/A

0DataRank · unranked

2 citations

Jianan Cheng, Klaudia Strucinska, Narcis I. Popescu, Lihua Wu, Qunhua Ke +7 more

Parallel Gene Expression Changes in Ventral Midbrain Dopamine and GABA Neurons during Normal Aging

eNeuro(2025)10.1523/eneuro.0107-25.2025

N/A

0DataRank · unranked

1 citations

Harris E. Blankenship, Kevin D. Pham, Kelsey A Carter, Willard M. Freeman, Michael J. Beckstead +1 more

Methylation array signals are predictive of chronological age without bisulfite conversion

GeroScience(2025)10.1007/s11357-025-01785-5

N/A

0DataRank · unranked

0 citations

Victor A. Ansere, Ram Babu Undi, Walker Hoolehan, Cory B. Giles, Chase A. Brown +5 more

Protocol to isolate oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons from a single mouse brain using magnetic-activated cell sorting

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.08.666877

N/A

0DataRank · unranked

0 citations

Dominika Siodłak, Kevin D. Pham, Casandra Salinas-Salinas, Sarah R. Ocañas, Willard M. Freeman +2 more

Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.26.690789

N/A

0DataRank · unranked

0 citations

Sabira Mohammed, Chao Jiang, Shylesh Bhaskaran, Constantin Georgescu, Megan John +12 more

Single Cell RNAseq Analysis of Thyroid Hormone Effects on Retinal Glial Cells

Aging and Disease(2025)10.14336/ad.2025.1221

N/A

0DataRank · unranked

0 citations

Shujuan Li, Yun Le, David R. Stanford, Willard M. Freeman, Xi‐Qin Ding +1 more

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

eLife(2020)10.7554/elife.59616

N/A

0DataRank · unranked

52 citations

Niran Hadad, Molly Nelson Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal +8 more

Heart and neural crest derivative 2‐induced preservation of sympathetic neurons attenuates sarcopenia with aging

Journal of Cachexia Sarcopenia and Muscle(2020)10.1002/jcsm.12644

N/A

0DataRank · unranked

18 citations

Zhong‐Min Wang, Marı́a Laura Messi, Henry Jacob Bonilla, Liang Liu, Willard M. Freeman +2 more

Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer

Scientific Reports(2020)10.1038/s41598-020-65536-6

N/A

0DataRank · unranked

27 citations

Xiaomeng Li, Sangphil Oh, Bin Zhang, Willard M. Freeman, Sook Shin +2 more

Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging

Aging Cell(2021)10.1111/acel.13492

N/A

0DataRank · unranked

71 citations

Chase A. Brown, Xiavan Roopnarinesingh, Cory B. Giles, Constantin Georgescu, Willard M. Freeman +2 more

Long‐term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice

Journal of Cachexia Sarcopenia and Muscle(2021)10.1002/jcsm.12790

N/A

0DataRank · unranked

20 citations

Marı́a Laura Messi, Zhong‐Min Wang, Henry Jacob Bonilla, Willard M. Freeman, Osvaldo Delbono +1 more

Litter expansion alters metabolic homeostasis in a sex specific manner

PLoS ONE(2021)10.1371/journal.pone.0237199

N/A

0DataRank · unranked

7 citations

Shivani N. Mann, Jordan Jackson, Stephanie Matyi, Michelle Ranjo‐Bishop, Willard M. Freeman +4 more

Minimizing the ex vivo confounds of cell-isolation techniques on transcriptomic -profiles of purified microglia

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.15.452509

N/A

0DataRank · unranked

8 citations

Kevin D. Pham, Harris E. Blankenship, Adeline H. Machalinski, Ana J. Chucair‐Elliott, Willard M. Freeman +1 more

Differential regulation of mouse hippocampal gene expression sex differences by chromosomal content and gonadal sex

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.01.458115

N/A

0DataRank · unranked

2 citations

Victor A. Ansere, Kyla B. Tooley, Niran Hadad, Ana J. Chucair‐Elliott, David R. Stanford +8 more

The NOTCH3 Downstream Target HEYL Regulates Human Airway Epithelial Club Cell Differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.10.434858

N/A

0DataRank · unranked

0 citations

Subramaniyan Bharathiraja, A. Moore, Jordan P. Metcalf, Sarah R. Ocañas, Willard M. Freeman +4 more

Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex

Molecular Neurobiology(2022)10.1007/s12035-022-02860-0

N/A

0DataRank · unranked

30 citations

Victor A. Ansere, Kyla B. Tooley, Niran Hadad, Ana J. Chucair‐Elliott, David R. Stanford +8 more

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.16.496423

N/A

0DataRank · unranked

1 citations

Roshini Sathiaseelan, Shivani N. Mann, Maria Kamal, Wenyi Luo, Tatiana D. Saccon +7 more

Blocking necroptosis reduces inflammation and tumor incidence in a mouse model of diet-induced hepatocellular carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.03.502666

N/A

0DataRank · unranked

0 citations

Nidheesh Thadathil, Albert L. Tran, Michael Van Der Veldt, Constantin Georgescu, Nair H Haritha +11 more