Lorenzo Leggio

Also affiliated with National Institute on Alcohol Abuse and Alcoholism

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.6Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021

Clinical and Molecular Hepatology(2025)10.3350/cmh.2024.0835

Top 23%

0.872DataRank

Top 23%60 citations

Luis Antonio Díaz, Kanokphong Suparan, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Thanida Auttapracha +18 more

Papers

Driven by 114 papers — median percentile 74. Top paper: “Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021”.

Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021

Clinical and Molecular Hepatology(2025)10.3350/cmh.2024.0835

Top 23%

0.872DataRank

Top 23%60 citations

Luis Antonio Díaz, Kanokphong Suparan, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Thanida Auttapracha +18 more

OUP accepted manuscript

Alcohol and Alcoholism(2021)10.1093/alcalc/agab038

Top 28%

0.705DataRank

Top 28%14 citations

Ethan H. Mereish, Monica L. Faulkner, Shervin Assari, Kelvin Choi, Lorenzo Leggio +2 more

A Population Pharmacokinetic Analysis of PF-5190457, a Novel Ghrelin Receptor Inverse Agonist in Healthy Volunteers and in Heavy Alcohol Drinkers

Clinical Pharmacokinetics(2020)10.1007/s40262-020-00942-7

N/A

0.633DataRank · unranked

12 citations

Mary R. Lee, Lorenzo Leggio, Fatemeh Akhlaghi, Enoch Cobbina

Mifepristone as a pharmacological intervention for stress‐induced alcohol craving: A human laboratory study

Addiction Biology(2023)10.1111/adb.13288

N/A

0.578DataRank · unranked

19 citations

Molly Magill, Nazzareno Cannella, Joshua C. Brown, Elie Aoun, Patricia A. Cioe +5 more

Anabolic androgenic steroids used as performance and image enhancing drugs in professional and amateur athletes: Toxicological and psychopathological findings

Human Psychopharmacology Clinical and Experimental(2021)10.1002/hup.2815

N/A

0.520DataRank · unranked

31 citations

Gabriele Sani, Georgios D. Kotzalidis, Simone Cappelletti, Livia Longo, Salvatore Rizzato +5 more

A randomized, double-blind, placebo-controlled study of a GHSR blocker in people with alcohol use disorder

JCI Insight(2024)10.1172/jci.insight.182331

N/A

0.402DataRank · unranked

11 citations

Mehdi Farokhnia, Mary R. Lee, Lisa Farinelli, Brittney D. Browning, Kelly M. Abshire +13 more

The effect of alcohol, tobacco, and other drug use on vaccine acceptance, uptake, and adherence: a systematic review

Alcohol and Alcoholism(2024)10.1093/alcalc/agae057

N/A

0.345DataRank · unranked

9 citations

Jenna E. Sanfilippo, Paul Juneau, Garrick Sherman, Diane Cooper, Lorenzo Leggio +1 more

Oxytocin Reduces Methylphenidate-Induced Dorsal Striatal Dopamine Release in Male Rhesus Macaques

The International Journal of Neuropsychopharmacology(2024)10.1093/ijnp/pyae056

N/A

0.208DataRank · unranked

3 citations

Ehsan Shokri‐Kojori, William J. Dieckmann, Erick Singley, Julie A. Mattison, Peter Herscovitch +2 more

Understanding plasma treatment effect on human acyl-ghrelin concentrations.

PubMed(2020)10.26355/eurrev_202002_20216

N/A

0DataRank · unranked

10 citations

Lorenzo Leggio, Sara L. Deschaine

Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β‐Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders

American Journal on Addictions(2020)10.1111/ajad.13064

N/A

0DataRank · unranked

8 citations

Roberta Perciballi, Zoe E. Brown, Mary R. Lee, William H. Zywiak, Jonathan D. Kurtis +3 more

Differences in Sociodemographic and Alcohol‐Related Clinical Characteristics Between Treatment Seekers and Nontreatment Seekers and Their Role in Predicting Outcomes in the COMBINE Study for Alcohol Use Disorder

Alcoholism Clinical and Experimental Research(2020)10.1111/acer.14428

N/A

0DataRank · unranked

29 citations

Daria Piacentino, Xiaobai Li, Victoria M. Long, Mary R. Lee, Robert M. Swift +3 more

Development of a Physiologically Based Pharmacokinetic Model for Prediction of Ethanol Concentration-Time Profile in Different Organs

Alcohol and Alcoholism(2020)10.1093/alcalc/agaa129

N/A

0DataRank · unranked

6 citations

Lorenzo Leggio, Fatemeh Akhlaghi, Armin Sadighi

Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity

Drug and Alcohol Dependence(2020)10.1016/j.drugalcdep.2020.108155

N/A

0DataRank · unranked

5 citations

Mikela A. Murphy, Lorenzo Leggio, Joshua C. Gray

Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.30.228494

N/A

0DataRank · unranked

0 citations

Sara L. Deschaine, Adriana Gregory‐Flores, Lia J. Zallar, Zhi‐Bing You, Hui Sun +15 more

Addiction as a brain disease revised: why it still matters, and the need for consilience

Neuropsychopharmacology(2021)10.1038/s41386-020-00950-y

N/A

0DataRank · unranked

281 citations

James MacKillop, Diana Martínez, Jürgen Rehm, Lorenzo Leggio, Louk J. M. J. Vanderschuren +1 more

Bots and Misinformation Spread on Social Media: Implications for COVID-19

Journal of Medical Internet Research(2021)10.2196/26933

N/A

0DataRank · unranked

223 citations

Salvatore Giorgi, Amanda Devoto, Muhammad Mahbubur Rahman, Lyle Ungar, H. Andrew Schwartz +4 more

Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation

Nature Reviews Gastroenterology & Hepatology(2021)10.1038/s41575-021-00527-0

N/A

0DataRank · unranked

119 citations

Manhal Izzy, Lorenzo Leggio, Ramón Bataller, Vijay H. Shah, Juan Pablo Arab

Blood Biomarkers of Alcohol Use: A Scoping Review

Current Addiction Reports(2021)10.1007/s40429-021-00402-7

N/A

0DataRank · unranked

66 citations

Lorenzo Leggio, Mehdi Farokhnia, Julia C. Harris

Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trials

Neuroscience & Biobehavioral Reviews(2021)10.1016/j.neubiorev.2021.11.019

N/A

0DataRank · unranked

20 citations

Riccardo Presciuttini, Pier Paolo Pani, Julia Sinclair, Lorenzo Leggio, Roberta Agabio +1 more

From “Hunger Hormone” to “It’s Complicated”: Ghrelin Beyond Feeding Control

Physiology(2021)10.1152/physiol.00024.2021

N/A

0DataRank · unranked

46 citations

Lorenzo Leggio, Sara L. Deschaine

The influence of anxiety symptoms on clinical outcomes during baclofen treatment of alcohol use disorder: A systematic review and meta-analysis

Neuroscience & Biobehavioral Reviews(2021)10.1016/j.neubiorev.2020.12.030

N/A

0DataRank · unranked

34 citations

David S. Baldwin, Hugo Amaro, Lorenzo Leggio, Julia Sinclair, Roberta Agabio

A closer look at alcohol‐induced changes in the ghrelin system: novel insights from preclinical and clinical data

Addiction Biology(2021)10.1111/adb.13033

N/A

0DataRank · unranked

29 citations

Mehdi Farokhnia, Adriana Gregory‐Flores, Lia J. Zallar, Zhi‐Bing You, Hui Sun +15 more

Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking

Translational Psychiatry(2021)10.1038/s41398-021-01728-6

N/A

0DataRank · unranked

26 citations

Silvia Grant-Beurmann, Carlotta Vizioli, Xiaobai Li, Catherine F. Moore, Victor Ruiz‐Rodado +6 more

Effect of oral alcohol administration on plasma cytokine concentrations in heavy drinking individuals

Drug and Alcohol Dependence(2021)10.1016/j.drugalcdep.2021.108771

N/A

0DataRank · unranked

25 citations

Kelly M. Abshire, Mehdi Farokhnia, Fatemeh Akhlaghi, Lorenzo Leggio, Mary R. Lee

Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap?

Frontiers in Neuroscience(2021)10.3389/fnins.2021.656475

N/A

0DataRank · unranked

22 citations

Amanda K. Bacon, Lydia G. Bailey, Mark A. Coggiano, Amy Hauck Newman, Lorenzo Leggio +2 more

Effectiveness of spironolactone dispensation in reducing weekly alcohol use: a retrospective high-dimensional propensity score-matched cohort study

Neuropsychopharmacology(2021)10.1038/s41386-021-01117-z

N/A

0DataRank · unranked

22 citations

Mehdi Farokhnia, Andrea H. Kline‐Simon, Joseph Elson, Stacy Sterling, Lorenzo Leggio +3 more

Sensory cue reactivity: Sensitization in alcohol use disorder and obesity

Neuroscience & Biobehavioral Reviews(2021)10.1016/j.neubiorev.2021.02.014

N/A

0DataRank · unranked

20 citations

Peter Manza, Lorenzo Leggio, Alicia A. Livinski, Nora D. Volkow, Paule V. Joseph +1 more

Neuroendocrine Response to Exogenous Ghrelin Administration, Combined With Alcohol, in Heavy-Drinking Individuals: Findings From a Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study

The International Journal of Neuropsychopharmacology(2021)10.1093/ijnp/pyab004

N/A

0DataRank · unranked

19 citations

Kelly M. Abshire, Aaron Hammer, Sara L. Deschaine, Anitha Saravanakumar, Enoch Cobbina +6 more

Cardiovascular Consequences of Excessive Alcohol Drinking via Electrocardiogram

Journal of Addictions Nursing(2021)10.1097/jan.0000000000000384

N/A

0DataRank · unranked

14 citations

Daria Piacentino, Brittney D. Browning, Barbara B. Brewer, Lorenzo Leggio, Lisa A. Farinelli

A neuroimaging investigation into the role of peripheral metabolic biomarkers in the anticipation of reward in alcohol use

Drug and Alcohol Dependence(2021)10.1016/j.drugalcdep.2021.108638

N/A

0DataRank · unranked

10 citations

Reza Momenan, Lorenzo Leggio, Monica L. Faulkner

The GABA-B receptor agonist baclofen helps patients with alcohol use disorder: why these findings matter

Neuropsychopharmacology(2021)10.1038/s41386-021-01142-y

N/A

0DataRank · unranked

10 citations

Raye Z. Litten, Lorenzo Leggio

An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder

Psychopharmacology(2021)10.1007/s00213-021-06008-1

N/A

0DataRank · unranked

10 citations

Roberta Perciballi, Molly Magill, Antonella Loche, Roberto Cacciaglia, Lorenzo Leggio +2 more

Leptin Gene and Leptin Receptor Gene Polymorphisms in Alcohol Use Disorder: Findings Related to Psychopathology

Frontiers in Psychiatry(2021)10.3389/fpsyt.2021.723059

N/A

0DataRank · unranked

7 citations

Melanie L. Schwandt, Mehdi Farokhnia, Sara L. Deschaine, Colin A. Hodgkinson, Lorenzo Leggio +1 more

Effect of intravenous ghrelin administration, combined with alcohol, on circulating metabolome in heavy drinking individuals with alcohol use disorder

Alcoholism Clinical and Experimental Research(2021)10.1111/acer.14719

N/A

0DataRank · unranked

7 citations

Mehdi Farokhnia, Anton Klåvus, Seppo Auriola, Marko Lehtonen, Sara L. Deschaine +5 more

A population-based investigation of the association between alcohol intake and serum total ghrelin concentrations among cigarette-smoking, non-alcohol-dependent male individuals

Drug and Alcohol Dependence(2021)10.1016/j.drugalcdep.2021.108835

N/A

0DataRank · unranked

8 citations

Gwen Murphy, Stephanie J. Weinstein, Navan N. Shah, Dominick Parisi, Demetrius Albanes +2 more

Thiamine administration toallpatients with alcohol use disorder: why not?

The American Journal of Drug and Alcohol Abuse(2021)10.1080/00952990.2021.1978474

N/A

0DataRank · unranked

7 citations

Lorenzo Leggio, Roberta Agabio

The validity of the state–trait anxiety inventory and the brief scale for anxiety in an inpatient sample with alcohol use disorder

Addiction(2021)10.1111/add.15516

N/A

0DataRank · unranked

6 citations

Melanie L. Schwandt, Breanne Hobden, David S. Baldwin, Julia Sinclair, Roberta Agabio +2 more

Response to “Addiction is a social disease: just as tenable as calling it a brain disease”

Neuropsychopharmacology(2021)10.1038/s41386-021-01037-y

N/A

0DataRank · unranked

3 citations

James MacKillop, Diana Martínez, Jürgen Rehm, Lorenzo Leggio, Louk J. M. J. Vanderschuren +1 more

Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116465

N/A

0DataRank · unranked

2 citations

Fatemeh Akhlaghi, Lorenzo Leggio, Kenner C. Rice, Agnieszka Sulima

Alcohol-related changes in behaviors and characteristics from the baseline to the randomization session for treatment and non-treatment seeking participants with alcohol use disorder

The American Journal of Drug and Alcohol Abuse(2021)10.1080/00952990.2021.1961799

N/A

0DataRank · unranked

1 citations

Talia R. Vasaturo-Kolodner, George A. Kenna, Robert M. Swift, Lorenzo Leggio, Carolina L. Haass‐Koffler +1 more

Bots and Misinformation Spread on Social Media: Implications for COVID-19 (Preprint)

(2021)10.2196/preprints.26933

N/A

0DataRank · unranked

9 citations

Salvatore Giorgi, Amanda Devoto, Muhammad Mahbubur Rahman, Lyle Ungar, H. Andrew Schwartz +4 more

Hazardous drinking and alcohol use disorders

Nature Reviews Disease Primers(2022)10.1038/s41572-022-00406-1

N/A

0DataRank · unranked

199 citations

Roberta Agabio, Sarah W. Feldstein Ewing, Markus Heilig, John F. Kelly, Lorenzo Leggio +6 more

Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review

Pharmacological Reviews(2022)10.1124/pharmrev.121.000367

N/A

0DataRank · unranked

156 citations

Natalie E. Zlebnik, Mehdi Farokhnia, Lorenzo Leggio, Satoshi Ikemoto, Yavin Shaham +1 more

Barriers to the management of alcohol use disorder and alcohol-associated liver disease: strategies to implement integrated care models

The Lancet. Gastroenterology & hepatology(2022)10.1016/s2468-1253(21)00191-6

N/A

0DataRank · unranked

88 citations

Lorenzo Leggio, Ashwani K Singal, Andrea F DiMartini

Alcohol use disorder in community management of chronic liver diseases

Hepatology(2022)10.1002/hep.32531

N/A

0DataRank · unranked

50 citations

Jessica L. Mellinger, Lorenzo Leggio

Simultaneous Management of Alcohol Use Disorder and Liver Disease: A Systematic Review and Meta-analysis

Journal of Addiction Medicine(2022)10.1097/adm.0000000000001084

N/A

0DataRank · unranked

50 citations

Mohamed A. Abdallah, Lorenzo Leggio, Ashwani K. Singal, Mohamed A. Elfeki

The glucagon‐like peptide‐1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post‐mortem brain study

Addiction Biology(2022)10.1111/adb.13211

N/A

0DataRank · unranked

44 citations

Brittney D. Browning, Madeline E. Crozier, Hui Sun, Fatemeh Akhlaghi, Lorenzo Leggio +1 more

The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder

Biological Psychiatry(2022)10.1016/j.biopsych.2022.02.006

N/A

0DataRank · unranked

41 citations

Reesha R. Patel, Alessandra Matzeu, Sarah A. Wolfe, Dallece E. Curley, Sophia Khom +13 more

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies

Molecular Psychiatry(2022)10.1038/s41380-022-01736-y

N/A

0DataRank · unranked

41 citations

Christopher T. Rentsch, Vicky Chuong, M. Adrienne McGinn, Sophie K. Elvig, Eliza Douglass +10 more

Role of the ghrelin system in alcohol use disorder and alcohol‐associated liver disease: A narrative review

Alcoholism Clinical and Experimental Research(2022)10.1111/acer.14967

N/A

0DataRank · unranked

33 citations

Mehdi Farokhnia, Sara L. Deschaine, Raghav Bhargava, Marcela Rodríguez-Flores, Carol A. Casey +5 more

Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies

Molecular Psychiatry(2022)10.1038/s41380-022-01594-8

N/A

0DataRank · unranked

32 citations

Brittney D. Browning, ReJoyce Green, Lorenzo Leggio, Dieter J. Meyerhoff, Lindsay M. Squeglia +1 more

Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use

Scientific Reports(2022)10.1038/s41598-022-17190-3

N/A

0DataRank · unranked

30 citations

Samantha J. Fede, Erica N. Grodin, Brittney D. Browning, Madeline E. Crozier, Melanie L. Schwandt +4 more

Toward a consensus nomenclature for ghrelin, its non‐acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor

Journal of Neuroendocrinology(2022)10.1111/jne.13224

N/A

0DataRank · unranked

24 citations

Suzanne L. Dickson, Jeffrey M. Zigman, Lorenzo Leggio, The Ghrelin Nomenclature Consensus Group, Mario Perelló

Identifying Alcohol Use Disorder in Patients With Cirrhosis Reduces 30-Days Readmission Rate

Alcohol and Alcoholism(2022)10.1093/alcalc/agac015

N/A

0DataRank · unranked

17 citations

Andrea F. DiMartini, Lorenzo Leggio, Juan Pablo Arab, Yong‐Fang Kuo, Vijay H. Shah +1 more

Echocardiographic markers of early alcoholic cardiomyopathy: Six-month longitudinal study in heavy drinking patients

European Journal of Internal Medicine(2022)10.1016/j.ejim.2022.04.005

N/A

0DataRank · unranked

16 citations

Luisa Sestito, Christian Lauria, Claudia Tarli, Gabriele Vassallo, Mariangela Antonelli +9 more

Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches

Molecular Psychiatry(2022)10.1038/s41380-022-01438-5

N/A

0DataRank · unranked

14 citations

Eliot L. Gardner, Ewa Galaj, Allamar Moore, Tristram Buck, Chloe J. Jordan +5 more

The Need for Integrating Addiction Medicine and Hepatology

JAMA Network Open(2022)10.1001/jamanetworkopen.2022.13022

N/A

0DataRank · unranked

13 citations

M. Katherine Jung, Lorenzo Leggio

Changes in plasma ghrelin levels following surgical and non-surgical weight-loss in female rats predict alcohol use

Brain Research Bulletin(2022)10.1016/j.brainresbull.2022.07.019

N/A

0DataRank · unranked

9 citations

Nelli Horvath, Mehdi Farokhnia, Lorenzo Leggio, A. Hajnal, Elise R. Orellana

Oxytocin receptors mediate oxytocin potentiation of methylphenidate‐induced stimulation of accumbens dopamine in rats

Journal of Neurochemistry(2022)10.1111/jnc.15730

N/A

0DataRank · unranked

8 citations

Amanda K. Bacon, Lydia G. Bailey, Mary R. Lee, Andy Y. Chen, Lorenzo Leggio +2 more

The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission

JCI Insight(2023)10.1172/jci.insight.170671

N/A

0DataRank · unranked

208 citations

Mehdi Farokhnia, Sophia Khom, Claire Pince, Sophie K. Elvig, Roman Vlkolinský +6 more

GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders

Nature Medicine(2023)10.1038/s41591-023-02634-8

N/A

0DataRank · unranked

86 citations

Christian S. Hendershot, Mehdi Farokhnia, Anders Fink‐Jensen, Mette Kruse Klausen, Joseph P. Schacht +2 more

Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice

Neuropharmacology(2023)10.1016/j.neuropharm.2023.109643

N/A

0DataRank · unranked

36 citations

Agnieszka Sulima, Kenner C. Rice, Jed A. Kucharczk, Kim D. Janda, Khalin E. Nisbett +4 more

The vicious cycle between (neuro)inflammation and alcohol use disorder: An opportunity to develop new medications?

Alcohol Clinical and Experimental Research(2023)10.1111/acer.15049

N/A

0DataRank · unranked

21 citations

Lara A. Ray, Lorenzo Leggio, András H. Lékó

Sex difference in alcohol withdrawal syndrome: a scoping review of clinical studies

Frontiers in Psychiatry(2023)10.3389/fpsyt.2023.1266424

N/A

0DataRank · unranked

19 citations

Marie Michele Macaron, Hande Ayraler Taner, Duygu Kaba, Burcu Akın Sarı, Terry D. Schneekloth +3 more

Alcohol use disorder in alcohol-associated liver disease: Two sides of the same coin

Liver Transplantation(2023)10.1097/lvt.0000000000000296

N/A

0DataRank · unranked

24 citations

Lorenzo Leggio, Andrea F. DiMartini, Ashwani K. Singal

Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving

BMJ Mental Health(2023)10.1136/bmjment-2023-300852

N/A

0DataRank · unranked

19 citations

Mehdi Farokhnia, Susan Persky, Lorenzo Leggio, Brenda Curtis, Madeline E. Crozier

A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder

Drug and Alcohol Dependence(2023)10.1016/j.drugalcdep.2023.109809

N/A

0DataRank · unranked

15 citations

Tammy Wang, Tony Jourdan, Grzegorz Godlewski, Lisa A. Farinelli, George Kunos +2 more

Investigating the relationship between early life adversity, inflammation and alcohol use

Addiction Biology(2023)10.1111/adb.13274

N/A

0DataRank · unranked

13 citations

Daria Piacentino, Melanie L. Schwandt, Mary R. Lee, Monica L. Faulkner, Mehdi Farokhnia +2 more

Lifetime use of alcohol and cannabis among U.S. adolescents across age: Exploring differential patterns by sex and race/ethnicity using the 2019 NSDUH data

Drug and Alcohol Dependence Reports(2023)10.1016/j.dadr.2023.100214

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13 citations

Julia C. Harris, Shannon Speed, Lorenzo Leggio, Reneé M. Johnson, Mehdi Farokhnia

Brain proteomic atlas of alcohol use disorder in adult males

Translational Psychiatry(2023)10.1038/s41398-023-02605-0

N/A

0DataRank · unranked

12 citations

Waleed Barakat, Sophie M. Tran, Zoe M. Tran, Nicholas W. Bateman, Kelly A. Conrads +10 more

Role of aldosterone and mineralocorticoid receptor (MR) in addiction: A scoping review

Neuroscience & Biobehavioral Reviews(2023)10.1016/j.neubiorev.2023.105427

N/A

0DataRank · unranked

12 citations

K. Whiting, Tammy Wang, András H. Lékó, Lisa A. Farinelli, Diane Cooper +4 more

The adolescent and young adult microbiome and its association with substance use: a scoping review

Alcohol and Alcoholism(2023)10.1093/alcalc/agad055

N/A

0DataRank · unranked

8 citations

Anna E. Kirkland, ReJoyce Green, Melinda A. Engevik, Alexander V. Alekseyenko, Lorenzo Leggio +3 more

Alcohol Use Disorder and Posttraumatic Stress Disorder: A Relationship Unbonded by Oxytocin Blockade

Biological Psychiatry(2023)10.1016/j.biopsych.2023.04.012

N/A

0DataRank · unranked

2 citations

Mary R. Lee, Lorenzo Leggio, Leandro F. Vendruscolo

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

Research Square(2023)10.21203/rs.3.rs-3236045/v1

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0DataRank · unranked

0 citations

András H. Lékó, Adriana Gregory‐Flores, Renata C.N. Marchette, Juan L. Gomez, Janaina Vendruscolo +17 more

IUPHAR review – Glucagon-like peptide-1 (GLP-1) and substance use disorders: An emerging pharmacotherapeutic target

Pharmacological Research(2024)10.1016/j.phrs.2024.107312

N/A

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80 citations

Elizabeth H. Tressler, Leandro F. Vendruscolo, Lorenzo Leggio, Mehdi Farokhnia, Nicolaus Bruns

Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials

Addiction(2024)10.1111/add.16409

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48 citations

Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Reneé M. Johnson, Rosa M. Crum +2 more

Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement

Nature Reviews Gastroenterology & Hepatology(2024)10.1038/s41575-024-00936-x

N/A

0DataRank · unranked

48 citations

Katie Witkiewitz, Jessica L. Mellinger, Frank A. Anania, Ramón Bataller, Thomas G. Cotter +26 more

Novel medications for problematic alcohol use

Journal of Clinical Investigation(2024)10.1172/jci172889

N/A

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24 citations

Katie Witkiewitz, Lara A. Ray, Lorenzo Leggio, Markus Heilig

The glucagon‐like peptide‐1 and other endocrine responses to alcohol ingestion in women with versus without metabolic surgery

Addiction Biology(2024)10.1111/adb.13441

N/A

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19 citations

Neda Seyedsadjadi, Danisa Nieto, Lorenzo Leggio, Blair Rowitz, Marta Yanina Pepino +1 more

The crosstalk between fibroblast growth factor 21 (FGF21) system and substance use

iScience(2024)10.1016/j.isci.2024.110389

N/A

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16 citations

Ryan E. Tyler, Oyenike Ilaka, Diane Cooper, Mehdi Farokhnia, Lorenzo Leggio +1 more

Barriers to Alcohol Use Disorder Treatment in Patients with Alcohol-Associated Liver Disease

Clinics in Liver Disease(2024)10.1016/j.cld.2024.06.012

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9 citations

Lorenzo Leggio, András H. Lékó

GHSR blockade, but not reduction of peripherally circulating ghrelin via β1-adrenergic receptor antagonism, decreases binge-like alcohol drinking in mice

Molecular Psychiatry(2024)10.1038/s41380-024-02713-3

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10 citations

Lindsay A Kryszak, Janaina C. M. Vendruscolo, George F. Koob, Leandro F. Vendruscolo, Lorenzo Leggio +1 more

Integrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder

Hepatology(2024)10.1097/hep.0000000000000996

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14 citations

Lorenzo Leggio, Lamia Haque

Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial

Neuropsychopharmacology(2024)10.1038/s41386-024-01821-6

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13 citations

Adam Yngve, J. Paul Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg +9 more

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

Communications Biology(2024)10.1038/s42003-024-06303-5

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12 citations

Adriana Gregory‐Flores, Renata C.N. Marchette, Juan L. Gomez, Janaina C. M. Vendruscolo, Vez Repunte‐Canonigo +18 more

Gut microbial diversity and functional characterization in people with alcohol use disorder: A case-control study

PLoS ONE(2024)10.1371/journal.pone.0302195

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10 citations

Carlotta Vizioli, Jennifer J. Barb, Silvia Grant-Beurmann, Sofia Bouhlal, Jillian T. Battista +13 more

Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain

Brain Structure and Function(2024)10.1007/s00429-024-02876-3

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6 citations

Gimena Fernández, Ramiro E. Llovera, María José Tolosa, Sonia Cantel, Jean‐Alain Fehrentz +6 more

Parosmia Is Positively Associated With Problematic Drinking, as Is Phantosmia With Depressive Symptoms

Journal of Addiction Medicine(2024)10.1097/adm.0000000000001332

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5 citations

Jeremy W. Luk, B Stangl, Melanie L. Schwandt, Reza Momenan, David Goldman +6 more

Role of ghrelin hormone in the development of alcohol-associated liver disease

Biomedicine & Pharmacotherapy(2024)10.1016/j.biopha.2024.116595

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3 citations

Ramesh Bellamkonda, Kusum K. Kharbanda, Madan Kumar Arumugam, Vikas Kumar, Carol A. Casey +3 more

Bariatric surgery and alcohol and substance use: A case-control survey study

Drug and Alcohol Dependence(2024)10.1016/j.drugalcdep.2024.112529

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2 citations

Garrick Sherman, Tammy Wang, Claire Pince, Jenna E. Sanfilippo, Chiara Montemitro +6 more

Granulocyte-colony stimulating factor use in alcohol-associated hepatitis: is it time to promote liver regeneration?

The American Journal of Drug and Alcohol Abuse(2024)10.1080/00952990.2024.2308789

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1 citations

Juan Pablo Arab, Lorenzo Leggio, Luis Antonio Díaz

FGF21 responses to alcohol, an insight from a comparative study in individuals with alcohol use disorder

Alcohol(2024)10.1016/j.alcohol.2024.12.001

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1 citations

Lorenzo Leggio, Suthat Liangpunsakul

Amylin in Alcohol Addiction: A Potential New Treatment Target or an Adjuvant to Other Treatments?

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00133

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5 citations

Mehdi Farokhnia, Lorenzo Leggio, Selim R Boukabara

Crosstalk between alcohol use disorder and obesity: two sides of the same coin?

Molecular Psychiatry(2025)10.1038/s41380-025-03259-8

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8 citations

Mehdi Farokhnia, Paul J. Kenny, Marta Yanina Pepino, W. Kyle Simmons, Lorenzo Leggio

Circulating Immune and Endocrine Markers in Currently Drinking and Abstinent Individuals With Alcohol Use Disorder and Controls

Addiction Biology(2025)10.1111/adb.70039

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9 citations

Carlotta Vizioli, Jennifer J. Barb, Mehdi Farokhnia, Lorenzo Leggio, Ryan E. Tyler

Sex and gender differences in alcohol use disorder: Quo Vadis?

Alcohol(2025)10.1016/j.alcohol.2025.01.003

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5 citations

Lorenzo Leggio, Katie Witkiewitz

Glucagon-Like Peptide-1 Receptor Agonists and Alcohol Use: A Real-Word Observational Study in a Large, Integrated Health Care System

Biological Psychiatry Global Open Science(2025)10.1016/j.bpsgos.2025.100659

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3 citations

Brianna Costales, Stacy Sterling, Andrea H. Kline‐Simon, Lorenzo Leggio, Mehdi Farokhnia +1 more

Early signs of cardiovascular abnormalities in patients with alcohol misuse

Alcohol Clinical and Experimental Research(2025)10.1111/acer.70099

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2 citations

Garrick Sherman, Daria Piacentino, Melanie L. Schwandt, Valerie Espinal Abreu, Diane Cooper +2 more

Novel strategies for medical management of obesity: mechanisms, clinical implications, and societal impacts—a report from the 25th Annual Harvard Nutrition Obesity Symposium

American Journal of Clinical Nutrition(2025)10.1016/j.ajcnut.2025.06.015

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4 citations

Sophia L Campbell, Christine Hill, Takara L. Stanley, Elizabeth A. Lawson, Caroline M. Apovian +9 more

Evidence for independent actions of the CRF and ghrelin systems in binge-like alcohol drinking in mice

Progress in Neuro-Psychopharmacology and Biological Psychiatry(2025)10.1016/j.pnpbp.2025.111341

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3 citations

Lindsay A Kryszak, Janaina C. M. Vendruscolo, George F. Koob, Lorenzo Leggio, Leandro F. Vendruscolo +1 more

Exploring the Relationship Between Behavioral Inhibition and Approach Systems and Alcohol‐Related Outcomes in People With Alcohol Use Disorder

Brain and Behavior(2025)10.1002/brb3.70944

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1 citations

Lorenzo Leggio, Mehdi Farokhnia, Madeline E. Crozier

An exploratory analysis of the relationship between ultraprocessed food consumption, alcohol intake, body composition, and cardiometabolic markers in individuals with alcohol use disorder

Alcohol Clinical and Experimental Research(2025)10.1111/acer.70140

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2 citations

Lillian C. King, Shanna Yang, Sara Turner, Carlotta Vizioli, Ryan E. Tyler +5 more

Cocaine craving and use during pharmacotherapy trials for cocaine use disorder: A multi-trajectory analysis

Drug and Alcohol Dependence(2025)10.1016/j.drugalcdep.2025.112841

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1 citations

Ryoko Susukida, Mehdi Farokhnia, Trang Quynh Nguyen, Lorenzo Leggio, Cecilia L. Bergeria +3 more

Alcohol consumption and childhood trauma impact serum immunoglobulin levels in patients with alcohol use disorder

Alcohol Clinical and Experimental Research(2025)10.1111/acer.15537

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0 citations

Melanie L. Schwandt, Nancy Diazgranados, Mehdi Farokhnia, Lorenzo Leggio, Kelly M. Abshire

Preregistered multi-site preclinical randomized controlled trials: the beginning of a new day in reverse translational science?

Neuropsychopharmacology(2025)10.1038/s41386-025-02090-7

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0 citations

Giancarlo Colombo, Lorenzo Leggio

Interventions and Manipulations of Interoception

Trends in Neurosciences(2020)10.1016/j.tins.2020.09.010

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251 citations

Jack L. Feldman, Lorenzo Leggio, Vitaly Napadow, Jeanie Park, Cynthia Price +1 more

Plasma concentrations of the inflammatory adipokine lipocalin-2 are not affected by chronic alcohol exposure in rats or acute alcohol administration in people with alcohol use disorder

The American Journal of Drug and Alcohol Abuse(2025)10.1080/00952990.2025.2582563

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0 citations

Mehdi Farokhnia, Leandro F. Vendruscolo, Lorenzo Leggio, Rani S. Richardson

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

Nature Communications(2020)10.1038/s41467-020-15942-1

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135 citations

Tatiana A. Shnitko, Steven W. Blue, Amy V. Kaucher, Andrea J. Winchell, David W. Erikson +3 more

Long-Acting Glucagon-Like Peptide-1 Receptor Agonists Suppress Voluntary Alcohol Intake in Male Wistar Rats

Frontiers in Neuroscience(2020)10.3389/fnins.2020.599646

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100 citations

Mehdi Farokhnia, Joseph J. Munier, Yatendra Mulpuri, Lorenzo Leggio, Igor Spigelman +1 more

Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study

Translational Psychiatry(2020)10.1038/s41398-020-0756-3

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88 citations

Gray R. McDiarmid, Matthew N. Newmeyer, Vikas Munjal, Osama A. Abulseoud, Marilyn A. Huestis +2 more

New Challenges in Addiction Medicine: COVID-19 Infection in Patients With Alcohol and Substance Use Disorders—The Perfect Storm

American Journal of Psychiatry(2020)10.1176/appi.ajp.2020.20040417

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52 citations

Chiara Montemitro, Lorenzo Leggio, Primavera A. Spagnolo

Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individuals: Results from two human laboratory studies

Brain Research(2020)10.1016/j.brainres.2020.146851

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21 citations

Jeanelle Portelli, Mary R. Lee, Gray R. McDiarmid, Vikas Munjal, Kelly M. Abshire +6 more

Investigating the link between serum concentrations of brain-derived neurotrophic factor and behavioral measures in anxious alcohol-dependent individuals

Alcohol(2020)10.1016/j.alcohol.2020.07.009

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16 citations

Mehdi Farokhnia, Sara L. Deschaine, Jillian T. Battista, Mary R. Lee, Xiaobai Li +3 more

Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics

ACS Pharmacology & Translational Science(2020)10.1021/acsptsci.0c00017

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12 citations

Ki A. Goosens, Kenneth A. Jacobson, Lorenzo Leggio, Limei Zhang, Lee E. Eiden

Lorenzo Leggio

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