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Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116465Source: DataRank Database

Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457 is a research paper published in Bioorganic & Medicinal Chemistry (2021). On theSindex it has a DataRank of 0.165. It has been cited 2 times.

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0.165DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 0.18)OA: greenTopics (46)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.165

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (4)

Fatemeh Akhlaghi ORCID,Lorenzo Leggio ORCID,Kenner C. Rice ORCID,Agnieszka Sulima ORCID

Live enrichment

PubMed:34662828 PMC:PMC9837661 OpenAlex:https://openalex.org/W3207649043

Intramural NIH HHS

Grant: Z99 DA999999

FWCI

0.18

Citation Percentile

0.4%

Citation Trend

2022

2023

greenLicense: cc-by

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9837661

publisherhttps://api.elsevier.com/content/article/PII:S0968089621004739?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089621004739?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmc.2021.116465

Fields of Study

Regulation of Appetite and ObesityBiochemical Analysis and Sensing TechniquesPharmacological Effects of Natural CompoundsAlcoholismAzetidinesDose-Response Relationship, DrugHumansIndenesMolecular StructurePyrimidinesReceptors, GhrelinSpiro CompoundsStructure-Activity RelationshipThiazoles

MeSH Terms

AlcoholismAzetidinesDose-Response Relationship, DrugHumansIndenesPyrimidinesSpiro CompoundsStructure-Activity RelationshipThiazolesMolecular StructureReceptors, Ghrelin

Keywords

MetaboliteChemistryInverse agonistGhrelinAgonistIn vivoPharmacologyReceptorChemical synthesisAlcoholIn vitroStereochemistryEndocrinologyBiochemistryMedicineBiologySynthesisCharacterizationPf-5190457Alcohol Use Disorder (Aud)Hydroxy Metabolite Pf-6870961

Sustainable Development Goals

SDG 0: Good health and well-being