Gregory A. Newby

Also affiliated with Johns Hopkins Medicine, Johns Hopkins University Applied Physics Laboratory

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 45 papers. Top paper: “Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins”.

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

Cell(2022)10.1016/j.cell.2021.12.021

N/A

6.9DataRank · unranked

655 citations

Aditya Raguram, Susie Suh, Samuel W. Du, Jessie R. Davis, Elliot H. Choi +9 more

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature Biotechnology(2021)10.1038/s41587-021-00938-z

N/A

4.9DataRank · unranked

208 citations

Mandana Arbab, Max W. Shen, Jeffrey A. Hussmann, Andrew V. Anzalone, Jordan L. Doman +10 more

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

Nature Biotechnology(2022)10.1038/s41587-022-01533-6

N/A

3.8DataRank · unranked

267 citations

Alvin Hsu, Mandana Arbab, N Krasnow, Amber McElroy, Smriti Pandey +9 more

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

Genome biology(2021)10.1186/s13059-021-02304-3

N/A

2.7DataRank · unranked

99 citations

Qing Lyu, Amr R. Ghanam, Cícera R. Lazzarotto, Gregory A. Newby, Wei Zhang +13 more

In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice

Nature(2021)10.1038/s41586-020-03086-7

N/A

0.932DataRank · unranked

500 citations

Michael R. Erdos, Christopher Wilson, Wayne A. Cabral, Jonathan M. Levy, Zheng‐Mei Xiong +16 more

Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo

Nature Communications(2023)10.1038/s41467-023-43904-w

N/A

0.920DataRank · unranked

35 citations

Soumba Traore, Xue Cheng, Hadrien Benk-Fortin, Stéphanie Hallée, Mario Harvey +17 more

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

Nature Medicine(2023)10.1038/s41591-022-02190-7

N/A

0.786DataRank · unranked

188 citations

Gregory A. Newby, Hiroko Wakimoto, Mingyue Lun, Joshua M. Gorham, Justin J. Curran +13 more

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Nature Biomedical Engineering(2023)10.1038/s41551-023-01026-0

N/A

0.752DataRank · unranked

149 citations

Gregory A. Newby, Rachel M. Levine, Kalin Mayberry, Yoonjeong Jang, Thiyagaraj Mayuranathan +15 more

Base editing rescue of spinal muscular atrophy in cells and in mice

Science(2023)10.1126/science.adg6518

N/A

0.739DataRank · unranked

137 citations

Żaneta Matuszek, Kaitlyn M. Kray, Ailing Du, Gregory A. Newby, Anton J. Blatnik +12 more

Massively parallel base editing to map variant effects in human hematopoiesis

Cell(2023)10.1016/j.cell.2023.03.035

N/A

0.730DataRank · unranked

129 citations

Nicole Castano, Michael Pang, Emanuelle I. Grody, Samantha Joubran, Alexis Caulier +20 more

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

Nature Communications(2020)10.1038/s41467-020-15892-8

N/A

0.708DataRank · unranked

111 citations

Jordana M. Henderson, K. Coote, Yi Cheng, H. Valley, Xiao‐Ou Zhang +12 more

In vivo base editing extends lifespan of a humanized mouse model of prion disease

Nature Medicine(2025)10.1038/s41591-024-03466-w

N/A

0.696DataRank · unranked

42 citations

Jessie R. Davis, Jonathan M. Levy, Fiona E. Serack, John W. Harvey, Pamela P. Brauer +22 more

Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells

Nature Biomedical Engineering(2024)10.1038/s41551-024-01233-3

N/A

0.612DataRank · unranked

58 citations

Colin Hemez, Lei Lei, Soumba Traore, Katarina Kulhánková, Gregory A. Newby +7 more

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Molecular Therapy(2021)10.1016/j.ymthe.2021.10.026

N/A

0.581DataRank · unranked

47 citations

Gregory A. Newby, Cindy Eide, Amber McElroy, Sarah C. Nielsen, Kyle D. Smith +16 more

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Scientific Reports(2022)10.1038/s41598-022-24184-8

N/A

0.568DataRank · unranked

43 citations

Ina Guri, Paulina Żebrowska, Virginia Llopis-Hernández, Imogen Brooks, Stavroula Tekkela +14 more

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic Acids Research(2023)10.1093/nar/gkad1125

N/A

0.563DataRank · unranked

17 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +13 more

Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.05.438458

N/A

0.557DataRank · unranked

40 citations

Daniel Y. Kim, Kanae Sasaki, Matthew C. Canver, Xiao Wang, Hina Shah +14 more

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput

Nature Methods(2024)10.1038/s41592-024-02256-z

N/A

0.477DataRank · unranked

23 citations

Amin Alborzian Deh Sheikh, Matthew Balakar, Alexander C. Jones, Meagan E. Olive, Mudra Hegde +15 more

Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.07.372748

N/A

0.416DataRank · unranked

15 citations

Qing Lyu, Amr R. Ghanam, Cícera R. Lazzarotto, Gregory A. Newby, Wei Zhang +13 more

Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties

Frontiers in Genome Editing(2023)10.3389/fgeed.2023.1271813

N/A

0.396DataRank · unranked

13 citations

Christian M. Brommel, Soumba Traore, Gregory A. Newby, David R. Liu, Paul B. McCray +2 more

Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy

Nature Communications(2025)10.1038/s41467-025-59713-2

N/A

0.373DataRank · unranked

11 citations

Olivier Humbert, Jeffrey T. Ehmsen, Emily Fields, Sajeev Kohli, Stefan Radtke +14 more

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells

Nucleic Acids Research(2024)10.1093/nar/gkae819

N/A

0.345DataRank · unranked

9 citations

Anna X Cheng, Soumba Traore, Maud Auger, Mia Pelletier, Maxime Hervault +26 more

Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo

Research Square(2023)10.21203/rs.3.rs-2540755/v1

N/A

0.269DataRank · unranked

5 citations

Soumba Traore, Xue Cheng, Hadrien Benk-Fortin, Stéphanie Hallée, Mario Harvey +9 more

Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates

Science Translational Medicine(2025)10.1126/scitranslmed.adn2601

N/A

0.208DataRank · unranked

3 citations

Emily Fields, Kyle Swing, Greta Kanestrom, Jonathan Yen, Dnyanada Pande +7 more

Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499808

N/A

0.165DataRank · unranked

2 citations

Pawan K. Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby +12 more

Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

Epigenomics(2025)10.1080/17501911.2025.2603883

N/A

0DataRank · unranked

0 citations

Julia Nguyen, Elly H. Shin, Tyler Shin Nagano, Brent Selimi, Katie E. Hong +9 more

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

Cell Reports(2020)10.1016/j.celrep.2020.108001

N/A

0DataRank · unranked

6 citations

Timothy J. Eisen, Sven U. Heinrich, Zarina Brune, Erinc Hallacli, Gregory A. Newby +4 more

In vivo somatic cell base editing and prime editing

Molecular Therapy(2021)10.1016/j.ymthe.2021.09.002

N/A

0DataRank · unranked

192 citations

David R. Liu, Gregory A. Newby

Functional correction ofCFTRmutations in human airway epithelial cells using adenine base editors

Nucleic Acids Research(2021)10.1093/nar/gkab788

N/A

0DataRank · unranked

59 citations

Soumba Traore, Ashley L. Cooney, Christian M. Brommel, Katarina Kulhánková, Patrick L. Sinn +4 more

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Nature Communications(2022)10.1038/s41467-022-29490-3

N/A

0DataRank · unranked

94 citations

Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao +11 more

Comprehensive Analysis of CRISPR Base Editing Outcomes for Multimeric Protein

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.20.496792

N/A

0DataRank · unranked

4 citations

Mariya Moosajee, Gregory A. Newby, Kaivalya Molugu, Krishanu Saha, David R. Liu +2 more

Efficient prime editing in mouse brain, liver and heart with dual AAVs

Nature Biotechnology(2023)10.1038/s41587-023-01758-z

N/A

0DataRank · unranked

218 citations

Samagya Banskota, Jonathan M. Levy, Gregory A. Newby, Xiao Wang, Andrew V. Anzalone +9 more

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

Cell(2023)10.1016/j.cell.2023.02.027

N/A

0DataRank · unranked

83 citations

Gloria Yiu, Patrick Chang, Gregory A. Newby, Beatriz Campo-Fernández, Sorel Fitz‐Gibbon +18 more

Potent and uniform fetal hemoglobin induction via base editing

Nature Genetics(2023)10.1038/s41588-023-01434-7

N/A

0DataRank · unranked

77 citations

Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Cícera R. Lazzarotto +22 more

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Nature Biotechnology(2023)10.1038/s41587-023-01783-y

N/A

0DataRank · unranked

59 citations

Nicolas Mathey‐Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby +22 more

Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy

Journal of Clinical Investigation(2023)10.1172/jci171356

N/A

0DataRank · unranked

29 citations

Pawan K. Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby +12 more

Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.06.020

N/A

0DataRank · unranked

14 citations

Erin W. Kavanagh, Gregory A. Newby, Shakela Mitchell, Alice C. Eastman, Kathleen C. Paul +9 more

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.20.533459

N/A

0DataRank · unranked

1 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +11 more

Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo

Nature Biotechnology(2024)10.1038/s41587-023-02078-y

N/A

0DataRank · unranked

244 citations

Aditya Raguram, Samuel W. Du, Samagya Banskota, Jessie R. Davis, Gregory A. Newby +4 more

Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells

Nature Nanotechnology(2024)10.1038/s41565-024-01680-8

N/A

0DataRank · unranked

120 citations

Sumanta Chatterjee, Yehui Sun, Sean A. Dilliard, Stephen D. Moore, Yufen Xiao +17 more

Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

Nature Biomedical Engineering(2024)10.1038/s41551-024-01296-2

N/A

0DataRank · unranked

81 citations

Samuel W. Du, Jiin Felgner, Roman Šmidák, Elliot H. Choi, Grażyna Palczewska +19 more

In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2416827121

N/A

0DataRank · unranked

15 citations

Gregory A. Newby, David Salom, Fangyuan Gao, Carolline Rodrigues Menezes, Susie Suh +5 more

In vivo base editing of Angptl3 via lipid nanoparticles to treat cardiovascular disease

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102486

N/A

0DataRank · unranked

17 citations

Hanan Bloomer, Douglas Wich, Changfeng Huang, J. Noah Workman, Yamin Li +4 more

GFP-on mouse model for interrogation of in vivo gene editing

Nature Communications(2025)10.1038/s41467-025-61449-y

N/A

0DataRank · unranked

3 citations

Jack A. Queenan, Leah Swartzrock, Hana Willner, Morgane Denis, Nouraiz Ahmed +17 more

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

Nature Biomedical Engineering(2020)10.1038/s41551-020-00632-6

N/A

0DataRank · unranked

168 citations

Elliot H. Choi, Henri Leinonen, Andrzej T. Foik, Gregory A. Newby, Wei-Hsi Yeh +6 more