Sílvia Coma

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 11 papers. Top paper: “Preclinical efficacy of RAF/MEK clamp avutometinib in combination with FAK inhibition in low grade serous ovarian cancer”.

Preclinical efficacy of RAF/MEK clamp avutometinib in combination with FAK inhibition in low grade serous ovarian cancer

Gynecologic Oncology(2024)10.1016/j.ygyno.2024.01.028

N/A

0.879DataRank · unranked

31 citations

Cem Demirkiran, Tobias M.P. Hartwich, Stefania Bellone, Diego Manavella, Levent Mutlu +10 more

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

Blood(2022)10.1182/blood.2021011597

N/A

0.738DataRank · unranked

136 citations

Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar +14 more

The RAF/MEK clamp VS-6766 shows strong anti-tumor activity across multiple MAPK pathway alterations, with a preferential effect on KRAS G12V

European Journal of Cancer(2022)10.1016/s0959-8049(22)00851-6

N/A

0DataRank · unranked

0 citations

Mónica Musteanu, Alessia Mira, C. Caffarra, Deborah K. Morrison, Chiara Ambrogio +3 more

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101244

N/A

0DataRank · unranked

25 citations

Simone Lubrano, Michele Ceribelli, Damiano Cosimo Rigiracciolo, Robert Saddawi‐Konefka, Farhoud Faraji +18 more

Data from Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma

(2023)10.1158/1078-0432.c.6529851

N/A

0DataRank · unranked

0 citations

Monica Acosta, Robert Saddawi‐Konefka, Ayush Kishore, Simone Lubrano, Frederico Gomes +13 more

The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0870

N/A

0DataRank · unranked

33 citations

Larry Yan, Fadia Qiryaqos, Lars D. Engstrom, Jade Laguer, Andrew Calinisan +29 more

Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer

Cancer Medicine(2024)10.1002/cam4.70210

N/A

0DataRank · unranked

13 citations

Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara +7 more

FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma

Cancer Cell(2025)10.1016/j.ccell.2025.02.001

N/A

0DataRank · unranked

38 citations

Rodolfo Daniel Cervantes‐Villagrana, Farhoud Faraji, Sydney I. Ramirez, Kuniaki Sato, Sendi Rafael Adame-Garcia +15 more

Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ -Driven Uveal Melanoma

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-3363

N/A

0DataRank · unranked

77 citations

Monica Acosta, Robert Saddawi‐Konefka, Ayush Kishore, Simone Lubrano, Frederico Gomes +13 more

Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.101943

N/A

0DataRank · unranked

12 citations

Tursun Turapov, David A. Kircher, Karly A. Stanley, Katie M. Culver, A. Paulina Medellin +7 more

Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme

Nature Catalysis(2022)10.1038/s41929-022-00856-6

N/A

0DataRank · unranked

20 citations

Christos S. Karamitros, Kyle Ford, Catrina M. Somody, Ahlam N. Qerqez, Kyle Murray +20 more