Kenneth H. Pearce

University of North Carolina at Chapel Hill

Computer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.303Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12246

Top 55%

0.303DataRank

Top 55%5 citations

Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski +20 more

Papers

Driven by 39 papers — median percentile 45. Top paper: “Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways”.

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

Science(2007)10.1126/science.1150179

N/A

0.985DataRank · unranked

711 citations

Nan Wu, Joshua C. Curtin, Mohammed Qatanani, Nava R. Szwergold, Robert A. Reid +7 more

PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components

ACS Chemical Biology(2023)10.1021/acschembio.2c00804

N/A

0.590DataRank · unranked

50 citations

Caroline A. Foley, Han Wee Ong, Justin M. Rectenwald, Ronan P. Hanley, Jacqueline L. Norris‐Drouin +8 more

A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics

Nature Microbiology(2025)10.1038/s41564-025-02124-2

N/A

0.416DataRank · unranked

15 citations

Xiangbo Yang, Matthew J. G. Eldridge, Rongfeng Sun, Rachel T. Giorgio, B Morris +11 more

Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

Nature Communications(2025)10.1038/s41467-025-57005-3

N/A

0.330DataRank · unranked

8 citations

Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk +21 more

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12246

Top 55%

0.303DataRank

Top 55%5 citations

Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski +20 more

A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer's disease

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108356

N/A

0.241DataRank · unranked

4 citations

Nicole Hajicek, Andy P. Tsai, Padam P. Acharya, P. Brian Hardy, Emma Meyer +5 more

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

UNC Libraries(2020)10.17615/evfs-ha32

N/A

0.165DataRank · unranked

2 citations

Alicia Greenwalt, Michael B. Major, Kenneth H. Pearce, Yang Yang, Feng Yan +6 more

A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2’s Association with the HUSH Complex

ACS Chemical Biology(2021)10.1021/acschembio.1c00429

N/A

0DataRank · unranked

21 citations

Sarah E. Clinkscales, Kimberly D. Barnash, Gabrielle R. Budziszewski, Justin M. Rectenwald, Anna M. Chiarella +8 more

Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins

ACS Omega(2021)10.1021/acsomega.1c05381

N/A

0DataRank · unranked

10 citations

Sarah N. Dishman, Jarod M. Waybright, Isabelle A. Engelberg, Justin M. Rectenwald, Jacqueline L. Norris‐Drouin +5 more

A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.17.435897

N/A

0DataRank · unranked

3 citations

Deepika Jayaprakash, Robert M. Hollingworth, Steve Chen, Amy E. Jablonski, Yanzhe Gao +10 more

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

UNC Libraries(2021)10.17615/5h4x-0k36

N/A

0DataRank · unranked

0 citations

Ethan J. Fritch, Brett L. Hurst, Peter B. Madrid, Carolina Horta Andrade, Thomas R. Lane +20 more

Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00220

N/A

0DataRank · unranked

32 citations

Sandip Mukherjee, Daowei Huang, Molee Chakraborty, Chunfang Gu, Guangning Zong +7 more

Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00185

N/A

0DataRank · unranked

17 citations

Lilly F. Chiou, Percy Tumbale, Gaith N. Droby, Jiwoong Lim, Jacqueline L. Norris‐Drouin +6 more

Development of a high-throughput TR-FRET screening assay for a fast-cycling KRAS mutant

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.12.001

N/A

0DataRank · unranked

8 citations

P. Brian Hardy, Noah K. Schomburg, Xiaodong Wang, Dmitri Kireev, Kent L. Rossman +2 more

Computational and Experimental Approaches Identify Beta-Blockers as Potential SARS-CoV-2 Spike Inhibitors

ACS Omega(2022)10.1021/acsomega.2c01707

N/A

0DataRank · unranked

12 citations

Melina Mottin, Carolina Q. Sacramento, Tatyana Almeida Tavella, Gabriel Gonçalves Dias, Natalia Fintelman‐Rodrigues +11 more

A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors

UNC Libraries(2020)10.17615/m52q-g503

N/A

0DataRank · unranked

0 citations

Stephen V. Frye, Kenneth H. Pearce, Michael A. Stashko, Brandi M. Baughman, Yi An +4 more

Translational diffusion of bovine prothrombin fragment 1 weakly bound to supported planar membranes: measurement by total internal reflection with fluorescence pattern photobleaching recovery

UNC Libraries(2020)10.17615/8p56-wf98

N/A

0DataRank · unranked

0 citations

Kenneth H. Pearce, N.L. Thompson, Zeng Huang

SETDB1 Triple Tudor Domain Ligand, ( R , R )-59, Promotes Methylation of Akt1 in Cells

ACS Chemical Biology(2023)10.1021/acschembio.3c00280

N/A

0DataRank · unranked

15 citations

Yu Deng, Fengling Li, Devan J. Shell, Jacqueline L. Norris‐Drouin, Michael A. Stashko +7 more

Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot

Research Square(2023)10.21203/rs.3.rs-3197490/v1

N/A

0DataRank · unranked

2 citations

Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline L. Norris +4 more

SETDB1 Triple Tudor Domain Ligand, ( R,R )-59, Promotes Methylation of Akt1 in Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.10.539986

N/A

0DataRank · unranked

0 citations

Yu Deng, Fengling Li, Devan J. Shell, Jacqueline L. Norris‐Drouin, Michael A. Stashko +7 more

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121

N/A

0DataRank · unranked

31 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +24 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01346

N/A

0DataRank · unranked

28 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Meganathan Nandakumar, Anand Vala +12 more

In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot

Nature Communications(2024)10.1038/s41467-024-49892-9

N/A

0DataRank · unranked

11 citations

Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris‐Drouin, P. Brian Hardy +4 more

A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery

PLoS ONE(2024)10.1371/journal.pone.0308647

N/A

0DataRank · unranked

5 citations

P. Brian Hardy, S. Chubinskaya, Kenneth H. Pearce, Richard F. Loeser, Philip Coryell

PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling

Nucleic Acids Research(2024)10.1093/nar/gkae918

N/A

0DataRank · unranked

6 citations

Deepika Jayaprakash, Satpal S. Jhujh, John J. Reynolds, Steve Chen, Yanzhe Gao +13 more

Crystal structure of MAGEA4 MHD-RAD18 R6BD reveals a flipped binding mode compared to AlphaFold2 prediction

The EMBO Journal(2024)10.1038/s44318-024-00140-2

N/A

0DataRank · unranked

5 citations

Matthew C Fleming, Kenneth H. Pearce, Cyrus Vaziri, Albert A Bowers, Pei Zhou +1 more

A First-in-Class High-Throughput Screen to Discover Modulators of the Alternative Lengthening of Telomeres (ALT) Pathway

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00251

N/A

0DataRank · unranked

4 citations

C. Cook, Alyssa M. Cadiz, Katherine A. Flinter, Sara T. Ledeboer, Bianca Chan +8 more

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586341

N/A

0DataRank · unranked

7 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +20 more

Identification of Inhibitors of Chikungunya virus nsP2 ATPase

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.02.625520

N/A

0DataRank · unranked

4 citations

J. E. Scott, Ginger R. Smith, Pegah Ghiabi, Elisa Gibson, P. Loppnau +8 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.12.598722

N/A

0DataRank · unranked

2 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Eric M. Merten, John D. Sears +7 more

Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615363

N/A

0DataRank · unranked

2 citations

Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk +21 more

Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer

UNC Libraries(2024)10.17615/90en-6z38

N/A

0DataRank · unranked

0 citations

Richard G. Hodge, Jacob E. Larson, Michael J. Emanuele, Stephen V. Frye, McKenzie P. Kline +12 more

Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial β-Glucuronidases

Figshare(2024)10.17615/3qds-f928

N/A

0DataRank · unranked

0 citations

Lauren Lim, Matthew R. Redinbo, Samantha M. Ervin, Aadra P. Bhatt, Lindsey I. James +3 more

Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells

Research Square(2024)10.21203/rs.3.rs-5039962/v1

N/A

0DataRank · unranked

0 citations

Mélanie Uguen, Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li +21 more

A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery

UNC Libraries(2024)10.17615/rqaw-a983

N/A

0DataRank · unranked

0 citations

Kenneth H. Pearce, Philip Coryell, Richard F. Loeser, P. Brian Hardy, S. Chubinskaya

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.407361

N/A

0DataRank · unranked

21 citations

Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carol Queiroz Sacramento +19 more

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Scientific Reports(2025)10.1038/s41598-025-91673-x

N/A

0DataRank · unranked

9 citations

Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears +22 more

Structure–Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains

INDIGO (University of Illinois at Chicago)(2020)10.17615/4qgg-qe95

N/A

0DataRank · unranked

0 citations

Stephen V. Frye, Nancy Cheng, Jacqueline L. Norris‐Drouin, Jacob I. Stuckey, Catherine Simpson +6 more

Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins

Molecules(2020)10.3390/molecules25040979

N/A

0DataRank · unranked

23 citations

Shiva Krishna Reddy Guduru, Zhao Dang, Leonard B. Collins, Yi-En Liao, Jacqueline L. Norris‐Drouin +7 more

Kenneth H. Pearce

Indexed papers

Top data-sharing exemplar

Papers