🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Astrid M. Manuel

Baylor College of Medicine

ORCID: 0000-0001-8303-8116
Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile
2.0Author DataRank

Indexed papers

4in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

CSEA-DB: an omnibus for human complex trait and cell type associations

Nucleic Acids Research(2020)10.1093/nar/gkaa1064
Top 20%
1.0DataRank
Top 20%31 citations

Ruifeng Hu, Astrid M. Manuel, Andi Liu, Peilin Jia, Zhongming Zhao +1 more

Papers

Driven by 19 papers — median percentile 54. Top paper: “CSEA-DB: an omnibus for human complex trait and cell type associations”.

CSEA-DB: an omnibus for human complex trait and cell type associations

Nucleic Acids Research(2020)10.1093/nar/gkaa1064
Top 20%
1.0DataRank
Top 20%31 citations

Ruifeng Hu, Astrid M. Manuel, Andi Liu, Peilin Jia, Zhongming Zhao +1 more

Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data

The American Journal of Human Genetics(2020)10.1016/j.ajhg.2020.04.012
N/A
0.714DataRank · unranked
116 citations

Kathryn S. Burch, Ruth Johnson, Malika Freund, Gleb Kichaev, Nicholas Mancuso +4 more

Identifying candidate genes and drug targets for Alzheimer’s disease by an integrative network approach using genetic and brain region-specific proteomic data

Human Molecular Genetics(2022)10.1093/hmg/ddac124
Top 34%
0.585DataRank
Top 34%16 citations

Astrid M. Manuel, Yulin Dai, Brisa S. Fernandes, Nitesh Enduru, Peilin Jia +2 more

Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations

Nature Communications(2023)10.1038/s41467-023-38800-2
N/A
0.584DataRank · unranked
48 citations

Michael R. Brown, Taryn Alkis, Astrid M. Manuel, Xihao Li, Usman A. Tahir +31 more

A gene regulatory network approach harmonizes genetic and epigenetic signals and reveals repurposable drug candidates for multiple sclerosis

Human Molecular Genetics(2022)10.1093/hmg/ddac265
N/A
0.449DataRank · unranked
19 citations

Yulin Dai, Peilin Jia, Léorah Freeman, Zhongming Zhao, Astrid M. Manuel

Dense module searching for gene networks associated with multiple sclerosis

BMC Medical Genomics(2020)10.1186/s12920-020-0674-5
N/A
0.442DataRank · unranked
18 citations

Yulin Dai, Léorah Freeman, Peilin Jia, Zhongming Zhao, Astrid M. Manuel

Distinct effect of prenatal and postnatal brain expression across 20 brain disorders and anthropometric social traits: a systematic study of spatiotemporal modularity

Briefings in Bioinformatics(2021)10.1093/bib/bbab214
N/A
0.406DataRank · unranked
14 citations

Astrid M. Manuel, Brisa S. Fernandes, Yulin Dai, Zhongming Zhao, Peilin Jia

Prioritization of risk genes in multiple sclerosis by a refined Bayesian framework followed by tissue-specificity and cell type feature assessment

BMC Genomics(2022)10.1186/s12864-022-08580-y
N/A
0.373DataRank · unranked
11 citations

Astrid M. Manuel, Yulin Dai, Zhongming Zhao, Andi Liu

Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease

Science Advances(2025)10.1126/sciadv.adw4917
Top 58%
0.272DataRank
Top 58%5 citations

Citu Citu, Nitesh Enduru, Xian Chen, Chia-Hao Tung, Tirthankar Sinha +10 more

Identification and catalog of viral transcriptional regulators in human diseases

iScience(2025)10.1016/j.isci.2025.112081
N/A
0.241DataRank · unranked
4 citations

Le Chang, Astrid M. Manuel, Nitesh Enduru, Zhongming Zhao, Citu Citu

Montelukast as a repurposable additive drug for standard-efficacy multiple sclerosis treatment: Emulating clinical trials with retrospective administrative health claims data

Multiple Sclerosis Journal(2024)10.1177/13524585241240398
N/A
0.208DataRank · unranked
3 citations

Assaf Gottlieb, Léorah Freeman, Zhongming Zhao, Astrid M. Manuel

Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.25.600720
Top 78%
0.104DataRank
Top 78%1 citations

Citu Citu, Nitesh Enduru, Xian Chen, Astrid M. Manuel, Tirthankar Sinha +8 more

Disentangling accelerated cognitive decline from the normal aging process and unraveling its genetic components: A neuroimaging-based deep learning approach

Research Square(2023)10.21203/rs.3.rs-3328861/v1
N/A
0.104DataRank · unranked
1 citations

Yu‐Chun Hsu, Brisa S. Fernandes, Kai Zhang, Xiaoyang Li, Nitesh Enduru +5 more

Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer's disease

Research Square(2024)10.21203/rs.3.rs-4622123/v1
N/A
0DataRank · unranked
3 citations

Andi Liu, Citu Citu, Nitesh Enduru, Xian Chen, Astrid M. Manuel +8 more

Predicting regulatory variants using a dense epigenomic mapped CNN model elucidated the molecular basis of trait-tissue associations

Nucleic Acids Research(2020)10.1093/nar/gkaa1137
N/A
0DataRank · unranked
23 citations

Ruifeng Hu, Yulin Dai, Astrid M. Manuel, Zhongming Zhao, Peilin Jia +1 more

Enzalutamide-induced signatures revealed by epigenetic plasticity using single-cell multi-omics sequencing in prostate cancer

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.02.022
N/A
0DataRank · unranked
14 citations

Jinze Li, Astrid M. Manuel, Zhongming Zhao, Huihui Fan

WebCSEA: web-based cell-type-specific enrichment analysis of genes

Nucleic Acids Research(2022)10.1093/nar/gkac392
N/A
0DataRank · unranked
151 citations

Ruifeng Hu, Andi Liu, Kyung Serk Cho, Astrid M. Manuel, Xiaoyang Li +4 more

Unveiling Gene Interactions in Alzheimer’s Disease by Integrating Genetic and Epigenetic Data with a Network-Based Approach

Epigenomes(2024)10.3390/epigenomes8020014
N/A
0DataRank · unranked
2 citations

Astrid M. Manuel, Andi Liu, Boyan Leng, Xiangning Chen, Zhongming Zhao +1 more

Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach

Journal of Alzheimer s Disease(2024)10.3233/jad-231020
N/A
0DataRank · unranked
5 citations

Yu-Chun Hsu, Brisa S. Fernandes, Kai Zhang, Xiaoyang Li, Nitesh Enduru +6 more