Dmitri Kireev

Also affiliated with Joint Center for Structural Genomics, University of Missouri

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.303Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12246

Top 55%

0.303DataRank

Top 55%5 citations

Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski +20 more

Papers

Driven by 41 papers — median percentile 45. Top paper: “A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization”.

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Nature Chemical Biology(2021)10.1038/s41589-021-00898-0

N/A

0.705DataRank · unranked

109 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +35 more

PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components

ACS Chemical Biology(2023)10.1021/acschembio.2c00804

N/A

0.590DataRank · unranked

50 citations

Caroline A. Foley, Han Wee Ong, Justin M. Rectenwald, Ronan P. Hanley, Jacqueline L. Norris‐Drouin +8 more

MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer

Journal of Clinical Investigation(2022)10.1172/jci150517

N/A

0.581DataRank · unranked

47 citations

Justus M. Huelse, Dmitri Kireev, Zikang Tan, Luxiao Chen, Subir Goyal +10 more

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Nature Chemical Biology(2023)10.1038/s41589-023-01256-y

N/A

0.500DataRank · unranked

27 citations

Aleksandra Skrajna, Caroline A. Foley, Anh Nguyen, Gabrielle R. Budziszewski, Dalal N. Azzam +12 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00535

N/A

0.406DataRank · unranked

14 citations

Madhushika Silva, Ayaz Ahmad, Oscar E. A. Arce, Roly J. Armstrong, Cheryl Arrowsmith +105 more

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12246

Top 55%

0.303DataRank

Top 55%5 citations

Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski +20 more

A simulation model of heterochromatin formation at submolecular detail

iScience(2022)10.1016/j.isci.2022.104590

N/A

0.241DataRank · unranked

4 citations

Xiaokang Yan, Nathaniel A. Hathaway, Dmitri Kireev, Michael R. Williams

REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.23.432388

N/A

0.208DataRank · unranked

3 citations

Daniel Bsteh, Yibo Si, Bryce Hart, Tyler Weaver, Carina Pribitzer +22 more

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.433782

N/A

0.208DataRank · unranked

3 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +29 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq-v3

N/A

0.165DataRank · unranked

2 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

Biophysical Probes Reveal a “Compromise” Nature of the Methyl-lysine Binding Pocket in L3MBTL1

INDIGO (University of Illinois at Chicago)(2020)10.17615/bsf8-t806

N/A

0.165DataRank · unranked

2 citations

Dmitri Kireev, Tim J. Wigle, Cen Gao, Jacqueline L. Norris, Stephen V. Frye +1 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq

N/A

0.150DataRank · unranked

1 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

UNC Libraries(2020)10.17615/17wc-xm97

N/A

0DataRank · unranked

0 citations

Christopher J. MacNevin, Stephen V. Frye, William P. Janzen, Dalia Barsyte-Lovejoy, Xi‐Ping Huang +19 more

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

UNC Libraries(2020)10.17615/h6h3-eh02

N/A

0DataRank · unranked

0 citations

Peter A. DiMaggio, Dalia Barsyte-Lovejoy, Sylvie Rival‐Gervier, W. Tempel, Feng Liu +27 more

Small-molecule ligands of methyl-lysine binding proteins: Optimization of selectivity for L3MBTL3

Figshare(2021)10.17615/x6qe-4112

N/A

0DataRank · unranked

0 citations

Masoud Vedadi, Lindsey A. Ingerman, Robert Lam, Victoria Korboukh, J. Martin Herold +11 more

Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity

Nucleic Acids Research(2022)10.1093/nar/gkac198

N/A

0DataRank · unranked

51 citations

Yani Zhao, Cathy J. Spangler, Katarzyna M. Kedziora, Michael R. Williams, Dalal N. Azzam +9 more

Development of a high-throughput TR-FRET screening assay for a fast-cycling KRAS mutant

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.12.001

N/A

0DataRank · unranked

8 citations

P. Brian Hardy, Noah K. Schomburg, Xiaodong Wang, Dmitri Kireev, Kent L. Rossman +2 more

Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico

PNAS Nexus(2023)10.1093/pnasnexus/pgad062

N/A

0DataRank · unranked

4 citations

Michael R. Williams, Ameriks D Barboza Castillo, Dmitri Kireev, Nathaniel A. Hathaway, Xiaokang Yan

Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot

Research Square(2023)10.21203/rs.3.rs-3197490/v1

N/A

0DataRank · unranked

2 citations

Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline L. Norris +4 more

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c01267

N/A

0DataRank · unranked

26 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +91 more

In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot

Nature Communications(2024)10.1038/s41467-024-49892-9

N/A

0DataRank · unranked

11 citations

Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris‐Drouin, P. Brian Hardy +4 more

Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00148

N/A

0DataRank · unranked

10 citations

Qiang Tian, Zhilong Chen, Hongchao Zheng, Michael A. Stashko, Dan Yan +7 more

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson’s Disease associated protein

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.18.603797

N/A

0DataRank · unranked

5 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +90 more

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

UNC Libraries(2024)10.17615/jadh-1012

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Alison D. Axtman, Michael P. East, Benjamin Lee, Denis O. Okumu +12 more

The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia

UNC Libraries(2024)10.17615/dgnw-zr34

N/A

0DataRank · unranked

0 citations

Craig T. Jordan, Stephen V. Frye, Catherine C. Smith, Dmitri Kireev, Katherine A. Minson +12 more

Structural basis of paralog-specific KDM2A/B nucleosome recognition

UNC Libraries(2024)10.17615/n5q3-1z22

N/A

0DataRank · unranked

0 citations

Dmitri Kireev, Caroline A. Foley, Gabrielle R. Budziszewski, Lindsey I. James, Eyla C. Arteaga +12 more

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

Chemical Science(2025)10.1039/d4sc07532c

N/A

0DataRank · unranked

5 citations

Marta Glavatskikh, Xiaowen Wang, Antonio Jesús Lara Ordóñez, Fengling Li, Irene Chau +17 more

Discovery of Novel TYRO3/MERTK Dual Inhibitors

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00009

N/A

0DataRank · unranked

4 citations

Jichen Zhao, Daowei Huang, Michael A. Stashko, Dan Yan, Ransheng Ding +11 more

UNC9426, a Potent and Orally Bioavailable TYRO3-Specific Inhibitor

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00048

N/A

0DataRank · unranked

2 citations

Xiangbo Yang, Samantha Judd, Dan Yan, Stephanie Springborn, Michael A. Stashko +8 more

Exploiting structural variability in the kinase back-pocket to modulate polypharmacology of TAM inhibitors

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117561

N/A

0DataRank · unranked

0 citations

Dehui� Zhang, Zhilong Chen, Andrew L. McIver, Justus M. Huelse, Jyoti Mahajan +12 more

Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins

Molecules(2020)10.3390/molecules25040979

N/A

0DataRank · unranked

23 citations

Shiva Krishna Reddy Guduru, Zhao Dang, Leonard B. Collins, Yi-En Liao, Jacqueline L. Norris‐Drouin +7 more

Integrating DNA-encoded chemical libraries with virtual combinatorial library screening: Optimizing a PARP10 inhibitor

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127464

N/A

0DataRank · unranked

15 citations

Hannah Ravenscroft, Nicole J. Rueb, Dmitri Kireev, Dana Ferraris, Raphael M. Franzini +1 more

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

INDIGO (University of Illinois at Chicago)(2020)10.17615/0ecj-ye88

N/A

0DataRank · unranked

5 citations

C.H. Arrowsmith, Irene Chau, Guillermo Senisterra, Masoud Vedadi, Jian Jin +16 more

High-Throughput Screening for RecA Inhibitors Using a Transcreener Adenosine 5′- O -Diphosphate Assay

UNC Libraries(2020)10.17615/vpj4-6n34

N/A

0DataRank · unranked

4 citations

Dmitri Kireev, Eliza J. R. Peterson, Scott F. Singleton, William P. Janzen

UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo

UNC Libraries(2020)10.17615/4pj9-cy35

N/A

0DataRank · unranked

3 citations

Sandra Christoph, Dmitri Kireev, Emily A. Hull-Ryde, Chao Yang, Deborah DeRyckere +16 more

Assessment of free energy predictors for ligand binding to a methyllysine histone code reader

UNC Libraries(2020)10.17615/3wtx-vj74

N/A

0DataRank · unranked

0 citations

J. Martin Herold, Dmitri Kireev, Cen Gao

Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3

UNC Libraries(2020)10.17615/g8fd-vy49

N/A

0DataRank · unranked

0 citations

William P. Janzen, Liubov Krichevsky, Jacqueline L. Norris, Victoria Korboukh, Dmitri Kireev +4 more

Identification of Non-Peptide Malignant Brain Tumor (MBT) Repeat Antagonists by Virtual Screening of Commercially Available Compounds

UNC Libraries(2020)10.17615/9qqd-7336

N/A

0DataRank · unranked

0 citations

J. Martin Herold, William P. Janzen, Stephen V. Frye, Dmitri Kireev, Jacqueline Norris‐Drouin +1 more

A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors

UNC Libraries(2020)10.17615/m52q-g503

N/A

0DataRank · unranked

0 citations

Stephen V. Frye, Kenneth H. Pearce, Michael A. Stashko, Brandi M. Baughman, Yi An +4 more

The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface

UNC Libraries(2020)10.17615/6838-7x37

N/A

0DataRank · unranked

0 citations

Aiping Dong, C.H. Arrowsmith, Brandi M. Baughman, Jacqueline L. Norris, Dmitri Kireev +6 more

Inhibitors of Streptococcus pneumoniae Surface Endonuclease EndA Discovered by High-Throughput Screening Using a PicoGreen Fluorescence Assay

UNC Libraries(2020)10.17615/hqb8-rh27

N/A

0DataRank · unranked

0 citations

Marika Midon, William P. Janzen, Scott F. Singleton, Alfred Pingoud, Lars C. Pedersen +3 more

Dmitri Kireev

Indexed papers

Top data-sharing exemplar

Papers