Hal M. Hoffman

Also affiliated with University of California San Diego, Rady Children's Hospital-San Diego

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 42 papers. Top paper: “The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist”.

The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist

Annals of the Rheumatic Diseases(2022)10.1136/annrheumdis-2021-221801

N/A

0.737DataRank · unranked

135 citations

Zehra Serap Arıcı, David Piskin, Sara Alehashemi, Daniel Aletaha, Karyl S. Barron +26 more

Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C

Journal of Clinical Investigation(2021)10.1172/jci147076

N/A

0.641DataRank · unranked

71 citations

Isaac Shamie, Jamie Casey Lee, Cameron J. Nowell, Weiqi Peng, Shiela Angulo +18 more

NOD‐like receptor protein 3 activation causes spontaneous inflammation and fibrosis that mimics human NASH

Hepatology(2022)10.1002/hep.32320

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0.626DataRank · unranked

64 citations

Angela Chu, Susanne Gaul, Nika Taghdiri, Avinash Toomu, Aleksandra Leszczynska +8 more

Differential Binding of NLRP3 to non-oxidized and Ox-mtDNA mediates NLRP3 Inflammasome Activation

Communications Biology(2023)10.1038/s42003-023-04817-y

N/A

0.590DataRank · unranked

50 citations

Julia Elise Cabral, Angelina Wang, Yiyang Zhang, H. Liang, Donya Nikbakht +4 more

The 2021 EULAR/American College of Rheumatology Points to Consider for Diagnosis, Management and Monitoring of the Interleukin‐1 Mediated Autoinflammatory Diseases: Cryopyrin‐Associated Periodic Syndromes, Tumour Necrosis Factor Receptor‐Associated Periodic Syndrome, Mevalonate Kinase Deficiency, and Deficiency of the Interleukin‐1 Receptor Antagonist

Arthritis & Rheumatology(2022)10.1002/art.42139

N/A

0.561DataRank · unranked

41 citations

Zehra Serap Arıcı, David Piskin, Sara Alehashemi, Daniel Aletaha, Karyl S. Barron +26 more

Cold Urticaria Syndromes: Diagnosis and Management

The Journal of Allergy and Clinical Immunology In Practice(2023)10.1016/j.jaip.2023.05.040

N/A

0.464DataRank · unranked

21 citations

Katherine Gribbons, Katayoun Yazdi-Nejad, Jasmin Kuemmerle‐Deschner, Alan A. Wanderer, Lori Broderick +2 more

Endothelial Cell Response in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children

International Journal of Molecular Sciences(2023)10.3390/ijms241512318

N/A

0.405DataRank · unranked

9 citations

Chisato Shimizu, Ming He, Hao Wang, Hal M. Hoffman, Adriana H. Tremoulet +3 more

Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells

Cell Reports(2024)10.1016/j.celrep.2024.114598

N/A

0.272DataRank · unranked

4 citations

Elsa Meneses‐Salas, Jennifer L. Johnson, Susanna Manenti, Mouad Ait Kbaich, Danni Chen +15 more

Single-Cell Transcriptomic Analysis of Livers During NLRP3 Inflammasome Activation Reveals a Novel Immune Niche

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.31.437725

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0.104DataRank · unranked

1 citations

Angela Chu, Susanne Gaul, Nika Taghdiri, Avinash Toomu, Aleksandra Leszczynska +7 more

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

Scientific Reports(2021)10.1038/s41598-021-94565-y

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0DataRank · unranked

32 citations

Ronghao Zheng, Hao Sheng, Zhen Wang, Alex Gonzalez, Ping Zhou +3 more

Targeting interleukin‐1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis

Journal of Cachexia Sarcopenia and Muscle(2021)10.1002/jcsm.12744

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0DataRank · unranked

24 citations

Hao Sheng, Ronghao Zheng, Zhen Wang, Alex Gonzalez, Ping Zhou +3 more

Activin A Signaling Provides an Interorgan Link Between Kidney and Muscle in CKD-Associated Muscle Wasting

American Journal of Kidney Diseases(2021)10.1053/j.ajkd.2021.09.007

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0DataRank · unranked

4 citations

Hal M. Hoffman, Robert H. Mak, Elliot A. Perens

Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.05.429989

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0DataRank · unranked

2 citations

Hao Sheng, Ronghao Zheng, Zhen Wang, Alex Gonzalez, Ping Zhou +3 more

The Human Milk Oligosaccharide 3’Sialyllactose Promotes Inflammation Resolution and Reduces Atherosclerosis Development in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.19.433472

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0DataRank · unranked

0 citations

Nathanael J. Spann, Chloe Autran, Bastian Ramms, Austin W.T. Chiang, Kaare V. Grunddal +13 more

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.05.429984

N/A

0DataRank · unranked

0 citations

Ronghao Zheng, Hao Sheng, Zhen Wang, Alex Gonzalez, Ping Zhou +3 more

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

Research Square(2021)10.21203/rs.3.rs-156249/v1

N/A

0DataRank · unranked

0 citations

Ronghao Zheng, Sheng Hao, Zhen Wang, Alex Gonzalez, Ping Zhou +3 more

IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting

Nature Reviews Rheumatology(2022)10.1038/s41584-022-00797-1

N/A

0DataRank · unranked

167 citations

Hal M. Hoffman, Lori Broderick

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

Journal of Allergy and Clinical Immunology(2022)10.1016/j.jaci.2022.09.002

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0DataRank · unranked

128 citations

Tiphanie P. Vogel, Valentine G.J. Santarlas, Rahul Mhaskar, M.R. Smith, Alexandre F. Carisey +95 more

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology(2022)10.1002/hep.32776

N/A

0DataRank · unranked

88 citations

Benedikt Kaufmann, María Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark +15 more

NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis

EMBO Reports(2022)10.15252/embr.202154446

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0DataRank · unranked

42 citations

Aleksandra Leszczynska, Agustina Reca, Laela M. Booshehri, Janset Onyuru, ZheHao Tan +10 more

Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.06.007

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0DataRank · unranked

45 citations

Lin Kui, Agustina Reca, Aleksandra Leszczynska, Andrea D. Kim, Laela M. Booshehri +7 more

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease

Journal of the American Heart Association(2022)10.1161/jaha.122.025408

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0DataRank · unranked

16 citations

Jihoon Kim, Ming He, Adriana H. Tremoulet, Hal M. Hoffman, John Y.-J. Shyy +2 more

NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils

Science Advances(2023)10.1126/sciadv.adj1397

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0DataRank · unranked

67 citations

Mary Speir, ZheHao Tan, Jamie Casey Lee, Cameron J. Nowell, Alyce A. Chen +21 more

The discovery of NLRP3 and its function in cryopyrin‐associated periodic syndromes and innate immunity

Immunological Reviews(2023)10.1111/imr.13292

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0DataRank · unranked

36 citations

Lori Broderick, Hal M. Hoffman, Christopher D. Putnam

BRP39 Regulates Neutrophil Recruitment in NLRP3 Inflammasome-Induced Liver Inflammation

Cellular and Molecular Gastroenterology and Hepatology(2023)10.1016/j.jcmgh.2023.12.002

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0DataRank · unranked

23 citations

Andrea D. Kim, Janset Onyuru, Hal M. Hoffman, Ariel E. Feldstein, Lin Kui

Long-term exposure to house dust mites accelerates lung cancer development in mice

Journal of Experimental & Clinical Cancer Research(2023)10.1186/s13046-022-02587-9

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0DataRank · unranked

16 citations

Wen Li, Natalie Albasha, Lindsey Griffin, Han Chang, Lauren Amaya +20 more

Antisense Oligonucleotide Therapy Decreases IL-1β Expression and Prolongs Survival in Mutant Nlrp3 Mice

The Journal of Immunology(2023)10.4049/jimmunol.2200550

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0DataRank · unranked

9 citations

Marta de los Reyes Jiménez, Laela M. Booshehri, Janset Onyuru, Aleksandra Leszczynska, Anna Uri +7 more

The human milk oligosaccharide 3′sialyllactose reduces low-grade inflammation and atherosclerosis development in mice

JCI Insight(2024)10.1172/jci.insight.181329

N/A

0DataRank · unranked

16 citations

Nathanael J. Spann, Chloe Autran, Tae Gyu Oh, Kaare V. Grunddal, Joanna Coker +28 more

Cell Death in Liver Disease and Liver Surgery

Biomedicines(2024)10.3390/biomedicines12030559

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0DataRank · unranked

14 citations

Yeon‐Kyung Choi, Janset Onyuru, Helmut Friess, Hal M. Hoffman, Daniel Hartmann +2 more

Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation

Nature Immunology(2025)10.1038/s41590-025-02179-7

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0DataRank · unranked

16 citations

Kosuke Watari, Masafumi Ohira, Jonathan S. Brito, Peng He, Janset Onyuru +4 more

Modulating NLRP3 splicing with antisense oligonucleotides to control pathological inflammation

Nucleic Acids Research(2025)10.1093/nar/gkaf1116

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0DataRank · unranked

2 citations

Janset Onyuru, Jessica L. Centa, Estela M. Viera, Christopher D. Putnam, Hal M. Hoffman +2 more

Development of a Mouse Model of Coccidioidomycosis Using an Inhalation Exposure System

Journal of Fungi(2025)10.3390/jof11080599

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0DataRank · unranked

1 citations

Priscila Rodriguez, Ka Pui Sharon Yau, Matthew Tate, Aaron F. Carlin, Joshua Fierer +5 more

Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.08.017

N/A

0DataRank · unranked

154 citations

Pui Y. Lee, Hal M. Hoffman, Peter A. Nigrović

Hormetic elevation of taurine restrains inflammaging by deactivating the NLRP3 inflammasome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.27.656381

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0DataRank · unranked

3 citations

Seungjin Ryu, Mingze Dong, Yun‐Hee Youm, Subhasis Mohanty, Rae Maeda +13 more

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

Journal of Hepatology(2020)10.1016/j.jhep.2020.07.041

N/A

0DataRank · unranked

549 citations

Aleksandra Leszczynska, Fernando Alegre, Benedikt Kaufmann, Casey D. Johnson, Leon A. Adams +13 more

ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model

JCI Insight(2020)10.1172/jci.insight.123294

N/A

0DataRank · unranked

75 citations

Lukas Geisler, Matthew D. McGeough, Casey D. Johnson, Anna Zagórska, Li Li +9 more

Pediatric recurrent fever and autoinflammation from the perspective of an allergist/immunologist

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.09.019

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0DataRank · unranked

37 citations

Hal M. Hoffman, Lori Broderick

Opportunistic Invasive Infection by Group A Streptococcus During Anti–Interleukin-6 Immunotherapy

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa511

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0DataRank · unranked

11 citations

Katherine L. Olivares, Victor Nizet, Hal M. Hoffman, Suhas M. Radhakrishna, Doris L. LaRock +1 more

Vitamin D ameliorates adipose browning in chronic kidney disease cachexia

Scientific Reports(2020)10.1038/s41598-020-70190-z

N/A

0DataRank · unranked

37 citations

Wei Ding, Hal M. Hoffman, Zhen Wang, Hao Sheng, Ronghao Zheng +8 more

Inhibition of the NLRP3 inflammasome prevents ovarian aging

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.26.062646

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0DataRank · unranked

18 citations

Elísabet Alcocer‐Gómez, Beatriz Castejón‐Vega, Jordi Muntané, Pedro Bullón, Chun Wang +6 more

Microbial Pathogen-Induced Necrotic Cell Death Mediated by the Inflammasome Components CIAS1/Cryopyrin/NLRP3 and ASC

UNC Libraries(2020)10.17615/1ndq-e693

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0DataRank · unranked

0 citations

Mohanish Deshmukh, Amy C. Morrison, Hal M. Hoffman, Malabi M. Venkatesan, Stephen B. Willingham +7 more

Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome

The Journal of Experimental Medicine(2021)10.1084/jem.20201466

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0DataRank · unranked

47 citations

Nicolas Gaudenzio, Nadine Serhan, Eva Conde, Ophélie Godon, Thomas Marichal +12 more