John Okombo

Also affiliated with Columbia University Irving Medical Center, CNR de la Résistance aux Antibiotiques, Columbia University

MedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 15 papers. Top paper: “Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining”.

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Research Square(2024)10.21203/rs.3.rs-5412515/v1

N/A

0.104DataRank · unranked

1 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Cell chemical biology(2021)10.1016/j.chembiol.2021.06.006

N/A

0DataRank · unranked

30 citations

Ioanna Deni, Charisse Flerida A. Pasaje, John Okombo, Jessica L. Bridgford, Nina F. Gnädig +28 more

Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages

PLoS Pathogens(2022)10.1371/journal.ppat.1010926

N/A

0DataRank · unranked

29 citations

Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath, Lindsey Orchard +6 more

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Science Translational Medicine(2023)10.1126/scitranslmed.adc9249

N/A

0DataRank · unranked

27 citations

Francisco M. Guerra, Matthew Abraham, Kuo‐Sen Huang, Frances Rocamora, Haoshuang Zhao +22 more

Towards next-generation treatment options to combat Plasmodium falciparum malaria

Nature Reviews Microbiology(2024)10.1038/s41579-024-01099-x

N/A

0DataRank · unranked

49 citations

David A. Fidock, John Okombo

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance

Science(2024)10.1126/science.adk9893

N/A

0DataRank · unranked

26 citations

Karla P. Godinez‐Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng +43 more

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

PLoS Pathogens(2024)10.1371/journal.ppat.1012627

N/A

0DataRank · unranked

8 citations

Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, John Okombo, Juliana Calit, Diana Fontinha +12 more

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission

Science Advances(2024)10.1126/sciadv.adq1383

N/A

0DataRank · unranked

4 citations

Antima Gupta, Laura Drought, Avnish Patel, John Okombo, Mariëtte van der Watt +42 more

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615529

N/A

0DataRank · unranked

0 citations

Sachel Mok, Tomas Yeo, Melanie J. Shears, Jin H. Jeon, Sunil Kumar Narwal +23 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

npj Drug Discovery.(2025)10.1038/s44386-025-00006-5

N/A

0DataRank · unranked

11 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity

Cell chemical biology(2025)10.1016/j.chembiol.2025.06.003

N/A

0DataRank · unranked

9 citations

Tiantian Jiang, Lushun Wang, Monica J. Bohmer, Subhoja Chakraborty, John Okombo +32 more

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

PLoS Pathogens(2025)10.1371/journal.ppat.1012216

N/A

0DataRank · unranked

5 citations

Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale +4 more

Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance

Research Square(2025)10.21203/rs.3.rs-7697517/v1

N/A

0DataRank · unranked

0 citations

John Okombo, Tolla Ndiaye, Tarrick Qahash, Igor M. R. Moura, Eva Gil‐Iturbe +24 more

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

Nature Communications(2020)10.1038/s41467-020-18624-0

N/A

0DataRank · unranked

77 citations

Saima Sidik, Boryana Petrova, Nina F. Gnädig, John Okombo, Alice L Herneisen +6 more

Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in Plasmodium HSP90 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.684657

N/A

0DataRank · unranked

0 citations

Amanda K. Lukens, Mariana Laureano de Souza, Alex Foy, Jason Hsiao, Tolla Ndiaye +18 more