🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Wenwei Lin

St. Jude Children's Research Hospital

ORCID: 0000-0001-8754-6150
Pharmacology, Toxicology and PharmaceuticsBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile
0.123Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.06.407973
Top 71%
0.123DataRank
Top 71%1 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +34 more

Papers

Driven by 15 papers — median percentile 29. Top paper: “Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases”.

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases

Nature Communications(2020)10.1038/s41467-020-18708-x
N/A
0.985DataRank · unranked
26 citations

Xin Huang, Wenwei Lin, Jaeki Min, Darcie J. Miller, Anand Mayasundari +10 more

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

Nature Communications(2021)10.1038/s41467-021-24168-8
N/A
0.624DataRank · unranked
63 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +35 more

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

Clinical and Translational Science(2021)10.1111/cts.13012
N/A
0.434DataRank · unranked
17 citations

Claudia Wing, John C. Panetta, Donnie Eddins, Wenwei Lin, Wenjian Yang +23 more

17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma

iScience(2020)10.1016/j.isci.2020.101996
N/A
0.425DataRank · unranked
16 citations

Ahmed Abu‐Zaid, Wenwei Lin, Jonathan Low, Alireza Abdolvahabi, Hongjian Jin +24 more

Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand

Structure(2023)10.1016/j.str.2023.08.020
N/A
0.406DataRank · unranked
14 citations

Shyaron Poudel, Yongtao Li, Wenwei Lin, Jing Wu, Darcie J. Miller +2 more

A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR

Nucleic Acids Research(2023)10.1093/nar/gkad1175
N/A
0.352DataRank · unranked
7 citations

Shyaron Poudel, Jing Wu, Darcie J. Miller, Wenwei Lin, Lei Yang +7 more

Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators

Structure(2025)10.1016/j.str.2025.09.011
N/A
0.165DataRank · unranked
2 citations

Efren Garcia-Maldonado, Wenwei Lin, Shyaron Poudel, Jing Wu, Darcie J. Miller +2 more

Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.06.407973
Top 71%
0.123DataRank
Top 71%1 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +34 more

Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader

ChemRxiv(2021)10.26434/chemrxiv-2021-zvq4t
N/A
0.104DataRank · unranked
1 citations

Huda Zahid, Wenwei Lin, Taosheng Chen, Daniel A. Harki, William C. K. Pomerantz +1 more

First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01926
N/A
0DataRank · unranked
10 citations

Kwan‐Young Jung, Yongtao Li, Wenwei Lin, Jing Wu, Shyaron Poudel +5 more

PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors

Nature Communications(2025)10.1038/s41467-025-64773-5
N/A
0DataRank · unranked
1 citations

Wenwei Lin, Kwan‐Young Jung, Shyaron Poudel, Guangwei Yang, Jing Wu +15 more

Hidden-driver inference reveals synergistic brain-penetrant therapies for medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.20.689490
N/A
0DataRank · unranked
0 citations

Yang Xu, Mingrui Zhu, Xinran Dong, Honglei Zhou, Brandon Bianski +14 more

Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2217804120
N/A
0DataRank · unranked
18 citations

Andrew D. Huber, Shyaron Poudel, Yongtao Li, J. Seetharaman, Darcie J. Miller +2 more

Structure-guided approach to modulate small molecule binding to the promiscuous pregnane X receptor

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.524030
N/A
0DataRank · unranked
0 citations

Wenwei Lin, Shyaron Poudel, Yongtao Li, J. Seetharaman, Darcie J. Miller +2 more

PROTAC-mediated activation, rather than degradation, of a nuclear receptor reveals complex ligand-receptor interaction network

Structure(2024)10.1016/j.str.2024.09.016
N/A
0DataRank · unranked
10 citations

Wenwei Lin, Shyaron Poudel, Darcie J. Miller, Taosheng Chen, Andrew D. Huber