Brian C. Searle

Also affiliated with Mayo Clinic in Florida, The Ohio State University

ChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.652Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s disease

Scientific Data(2023)10.1038/s41597-023-02057-7

Top 31%

0.652DataRank

Top 31%25 citations

Jea Park, Deanna L. Plubell, Brian C. Searle, C. Dirk Keene, Eric B. Larson +11 more

Papers

Driven by 39 papers — median percentile 69. Top paper: “Generating high quality libraries for DIA MS with empirically corrected peptide predictions”.

Generating high quality libraries for DIA MS with empirically corrected peptide predictions

Nature Communications(2020)10.1038/s41467-020-15346-1

N/A

0.844DataRank · unranked

276 citations

Kristian E. Swearingen, Christopher A. Barnes, Tobias Schmidt, Siegfried Gessulat, Bernhard Kuster +2 more

Profiling mouse brown and white adipocytes to identify metabolically relevant small ORFs and functional microproteins

Cell Metabolism(2023)10.1016/j.cmet.2022.12.004

N/A

0.657DataRank · unranked

79 citations

Sally Lyons‐Abbott, Angie L. Bookout, Eduardo Vieira de Souza, Cynthia J. Donaldson, Joan Vaughan +26 more

A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s disease

Scientific Data(2023)10.1038/s41597-023-02057-7

Top 31%

0.652DataRank

Top 31%25 citations

Jea Park, Deanna L. Plubell, Brian C. Searle, C. Dirk Keene, Eric B. Larson +11 more

Data‐Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome

PROTEOMICS(2025)10.1002/pmic.202400187

N/A

0.434DataRank · unranked

17 citations

J. Alfredo Blakeley‐Ruiz, Annaliese Meyer, Simina Vintila, Matthew R. McIlvin, Tim Van Den Bossche +6 more

A Multipathway Phosphopeptide Standard for Rapid Phosphoproteomics Assay Development

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100639

N/A

0.330DataRank · unranked

8 citations

Allis Chien, Antonius Koller, David H. Hawke, Anthony W. Herren, Jenny Kim Kim +10 more

Detection of Human Papillomavirus Integration in Brain Metastases from Oropharyngeal Tumors by Targeted Sequencing

Viruses(2021)10.3390/v13081536

N/A

0.312DataRank · unranked

7 citations

Brian C. Searle, Lisa DePledge, George Sun, Charles Cobbs, Mohsen Karimi +1 more

Evaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data-Independent Acquisition

Journal of Proteome Research(2023)10.1021/acs.jproteome.3c00357

N/A

0DataRank · unranked

231 citations

Eugen Damoc, Tabiwang N. Arrey, Anna Pashkova, Eduard Denisov, J. Petzoldt +17 more

Optimizing Linear Ion-Trap Data-Independent Acquisition toward Single-Cell Proteomics

Analytical Chemistry(2023)10.1021/acs.analchem.3c00842

N/A

0DataRank · unranked

19 citations

Zilu Ye, Elena Krismer, Anna-Kathrine Pedersen, Maik Pietzner, Jesper V. Olsen +3 more

Computational approaches to identify sites of phosphorylation

PROTEOMICS(2023)10.1002/pmic.202300088

N/A

0DataRank · unranked

10 citations

Brian C. Searle, Alex Joyce

A differential proteomics study of cerebrospinal fluid from individuals with Niemann‐Pick disease, Type C1

PROTEOMICS(2023)10.1002/pmic.202200378

N/A

0DataRank · unranked

8 citations

Melissa R. Pergande, Christopher A. Crutchfield, Brian C. Searle, Peter S. Backlund, Jaqueline A. Picache +8 more

Optimizing linear ion trap data independent acquisition towards single cell proteomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.21.529444

N/A

0DataRank · unranked

2 citations

Zilu Ye, Elena Krismer, Anna-Kathrine Pedersen, Maik Pietzner, Jesper V. Olsen +3 more

2019 Association of Biomolecular Resource FacilitiesMulti-Laboratory Data-Independent Acquisition ProteomicsStudy

Journal of Biomolecular Techniques JBT(2023)10.7171/3fc1f5fe.9b78d780

N/A

0DataRank · unranked

1 citations

Paul M. Stemmer, Brian C. Searle, Laura E. Herring, LeRoy Martin, Mukul K. Midha +7 more

Evaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data Independent Acquisition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.03.543570

N/A

0DataRank · unranked

32 citations

Eugen Damoc, Tabiwang N. Arrey, Anna Pashkova, Eduard Denisov, J. Petzoldt +17 more

Deep learning from harmonized peptide libraries enables retention time prediction of diverse post translational modifications

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.30.542978

N/A

0DataRank · unranked

21 citations

Ariana E. Shannon, Vic Spicer, Alicia Richards, Darien Yeung, Danielle L. Swaney +3 more

Scribe: next-generation library searching for DDA experiments

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.01.522445

N/A

0DataRank · unranked

4 citations

Ariana E. Shannon, Damien B. Wilburn, Brian C. Searle

Computational approaches to identify sites of phosphorylation

(2023)10.22541/au.168682321.19864274/v1

N/A

0DataRank · unranked

0 citations

Brian C. Searle, A.D. Joyce

Data acquisition approaches for single cell proteomics

PROTEOMICS(2024)10.1002/pmic.202400022

N/A

0DataRank · unranked

19 citations

Ariana E. Shannon, Brian C. Searle, Gautam Ghosh

Urine Proteomics Profiling Identifies Novel Acute Pancreatitis Diagnostic Biomarkers in a Pediatric Population

Gastroenterology(2024)10.1053/j.gastro.2024.05.015

N/A

0DataRank · unranked

7 citations

Madalyn G. Moore, Zobeida Cruz‐Monserrate, Jaimie D. Nathan, Brian C. Searle, Maisam Abu‐El‐Haija +1 more

Characterizing protein-protein interactions with thermal proteome profiling

Current Opinion in Structural Biology(2024)10.1016/j.sbi.2024.102946

N/A

0DataRank · unranked

4 citations

Brian C. Searle

Nanopore Protein Sequencing Achieves Significant New Milestones

Clinical Chemistry(2024)10.1093/clinchem/hvae041

N/A

0DataRank · unranked

4 citations

Brian C. Searle

Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.18.613707

N/A

0DataRank · unranked

6 citations

J. Alfredo Blakeley‐Ruiz, Annaliese Meyer, Simina Vintila, Matthew R. McIlvin, Tim Van Den Bossche +6 more

Results from a Multi-Laboratory Ocean Metaproteomic Intercomparison: Effects of LC-MS Acquisition and Data Analysis Procedures

(2024)10.5194/egusphere-2023-3148

N/A

0DataRank · unranked

4 citations

Jaclyn K. Saunders, Matthew R. McIlvin, Erin M. Bertrand, J. A. Breier, Margaret Mars Brisbin +36 more

Comment on egusphere-2023-3148

(2024)10.5194/egusphere-2023-3148-rc1

N/A

0DataRank · unranked

0 citations

Jaclyn K. Saunders, Matthew R. McIlvin, Erin M. Bertrand, J. A. Breier, Margaret Mars Brisbin +36 more

Rapid assay development for low input targeted proteomics using a versatile linear ion trap

Research Square(2024)10.21203/rs.3.rs-4702746/v1

N/A

0DataRank · unranked

0 citations

Ariana E. Shannon, Rachael Teodorescu, No-Joon Song, Lilian R. Heil, Cristina C. Jacob +4 more

Koina: Democratizing machine learning for proteomics research

Nature Communications(2025)10.1038/s41467-025-64870-5

N/A

0DataRank · unranked

9 citations

Kevin Yang, Tobias Kockmann, Christian Panse, Wassim Gabriel, Del Bold +20 more

Rapid assay development for low input targeted proteomics using a versatile linear ion trap

Nature Communications(2025)10.1038/s41467-025-58757-8

N/A

0DataRank · unranked

6 citations

Rachael Teodorescu, No Joon Song, Lilian R. Heil, Cristina C. Jacob, Philip M. Remes +4 more

Proteomic profiling of zinc homeostasis mechanisms in Pseudomonas aeruginosa through data-dependent and data-independent acquisition mass spectrometry

Metallomics(2025)10.1093/mtomcs/mfaf020

N/A

0DataRank · unranked

1 citations

Matthew R. McIlvin, Paloma Lopez, Brian C. Searle, Mak A. Saito, Annaliese Meyer

Proteomic profiling of zinc homeostasis mechanisms in Pseudomonas aeruginosa through data-dependent and data-independent acquisition mass spectrometry

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.13.632865

N/A

0DataRank · unranked

0 citations

Matthew R. McIlvin, Paloma Lopez, Brian C. Searle, Mak A. Saito, Annaliese Meyer

Improving proteomic dynamic range with Multiple Accumulation Precursor Mass Spectrometry (MAP-MS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.14.653938

N/A

0DataRank · unranked

0 citations

Ariana E. Shannon, Xinlei Zeng, Dong‐Jiunn Jeffery Truong, Erwin M. Schoof, Zilu Ye +2 more

Comparative Performance of Scribe and Database Search Engines in Metaproteomic Profiling of a Ground-Truth Microbiome Dataset

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.15.654320

N/A

0DataRank · unranked

0 citations

Subina Mehta, Reid Wagner, Wassim Gabriel, James E. Johnson, Katherine Do +7 more

Validation and Community Sharing of Ocean Spectral Libraries Generated by Machine Learning for Data Independent Acquisition Ocean Metaproteomic Analyses

PROTEOMICS(2025)10.1002/pmic.13971

N/A

0DataRank · unranked

0 citations

Matthew R. McIlvin, Damien B. Wilburn, Jaclyn K. Saunders, Natalie R. Cohen, Maya P. Bhatia +4 more

Harmonized Peptide Libraries Enable Practical Biofluid Selection for Developing Biomarker Assays

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.101086

N/A

0DataRank · unranked

0 citations

Ariana E. Shannon, Alex Joyce, Jessica M. Quimby, Brian C. Searle, Katelyn B Brusach

Comparative performance of Scribe and database search engines in metaproteomic profiling of a ground-truth microbiome dataset

Journal of Proteomics(2025)10.1016/j.jprot.2025.105549

N/A

0DataRank · unranked

0 citations

Subina Mehta, Reid Wagner, Wassim Gabriel, James E. Johnson, Katherine Do +7 more

Heightened protein synthesis and aggregation, coupled with futile protein quality control, underlie a novel mechanism of CD8+ T cell exhaustion 3479

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1279

N/A

0DataRank · unranked

0 citations

Anjun Ma, No Joon Song, Ariana E. Shannon, Yaa Amankwah, Jay K. Mandula +10 more

Quantitative Method for Assessing the Role of Lysine & Arginine Post-Translational Modifications in Nonalcoholic Steatohepatitis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.17.910943

N/A

0DataRank · unranked

0 citations

Aleksandra Binek, Vidya Venkatraman, Brian C. Searle, Ronald J. Holewinski, George Rosenberger +11 more

Data-independent acquisition protease-multiplexing enables increased proteome sequence coverage across multiple fragmentation modes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.15.452565

N/A

0DataRank · unranked

1 citations

Kuei-Ho Chen, Damien B. Wilburn, Erica Stevenson, Benjamin J. Polacco, Brian C. Searle +2 more

Recurrent Co-Option and Recombination of Cytokine and Three Finger Proteins in Multiple Reproductive Tissues Throughout Salamander Evolution

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.828947

N/A

0DataRank · unranked

6 citations

Christy L. Kunkel, Richard C. Feldhoff, Pamela W. Feldhoff, Brian C. Searle, Damien B. Wilburn

Profiling Mouse Brown and White Adipocytes to Identify Metabolically Relevant Small ORFs and Functional Microproteins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.12.484025

N/A

0DataRank · unranked

2 citations

Sally Lyons‐Abbott, Angie L. Bookout, Cynthia J. Donaldson, Joan Vaughan, Calvin J. Lau +24 more

Recurrent co-option and recombination of cytokine and three finger proteins in multiple reproductive tissues throughout salamander evolution

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.04.475003

N/A

0DataRank · unranked

1 citations

Christy L. Kunkel, Richard C. Feldhoff, Pamela W. Feldhoff, Brian C. Searle, Damien B. Wilburn

Brian C. Searle

Indexed papers

Top data-sharing exemplar

Papers