Yan Zhang

Also affiliated with Medicina

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 27 papers. Top paper: “Epidemiological Characteristics of Human Parainfluenza Viruses Infections — China, 2019–2023”.

Epidemiological Characteristics of Human Parainfluenza Viruses Infections — China, 2019–2023

China CDC Weekly(2024)10.46234/ccdcw2024.047

N/A

0.416DataRank · unranked

15 citations

Yingwei Ma, Daxing Feng, Feng Zhang, Biao Wang, Xiaoqing Liu +13 more

Exploration of Structure–Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01287

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0DataRank · unranked

13 citations

Mohini S. Ghatge, Qiukan Chen, Faik N. Musayev, Jürgen Venitz, Osheiza Abdulmalik +3 more

Structural elucidation and in vivo anti-arthritic activity of β-amyrin and polpunonic acid isolated from the root bark of Ziziphus abyssinica HochstEx. A Rich (Rhamnaceae)

Bioorganic Chemistry(2020)10.1016/j.bioorg.2020.103744

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0DataRank · unranked

19 citations

Boshi Huang, Faik N. Musayev, Rana Al Hashimi, Martin K. Safo, Francis Ackah Armah +5 more

Recent advances in multitarget-directed ligands targeting G-protein-coupled receptors

Drug Discovery Today(2020)10.1016/j.drudis.2020.07.004

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0DataRank · unranked

39 citations

Boshi Huang, Yan Zhang, Hongguang Ma

VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions

Scientific Reports(2020)10.1038/s41598-020-77171-2

N/A

0DataRank · unranked

25 citations

Piyusha P. Pagare, Boshi Huang, Guoyan Xu, Mohini S. Ghatge, Xiaomeng Xu +8 more

Structure activity relationship exploration of 5-hydroxy-2-(3-phenylpropyl)chromones as a unique 5-HT2B receptor antagonist scaffold

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127511

N/A

0DataRank · unranked

6 citations

Myles Truss, Piyusha P. Pagare, Martha A. Essandoh, Yan Zhang, Dwight A. Williams +1 more

Effective and Versatile Synthesis of Ginkgotoxin and Its 4′-O-Derivatives through Regioselective 4′-O-Alkylation and 4′-O-Chlorination of 3,5′-O-Dibenzylpyridoxine

SynOpen(2020)10.1055/s-0040-1707242

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0DataRank · unranked

2 citations

Boshi Huang, Richmond Danso‐Danquah, Martin K. Safo, Yan Zhang

Structure-Based Design and Development of Chemical Probes Targeting Putative MOR-CCR5 Heterodimers to Inhibit Opioid Exacerbated HIV-1 Infectivity

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00408

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0DataRank · unranked

13 citations

Huiqun Wang, Yi Zheng, Mengchu Li, Guifeng Kang, Victor Barreto‐de‐Souza +6 more

Exploring naltrexamine derivatives featuring azaindole moiety via nitrogen-walk approach to investigate their in vitro pharmacological profiles at the mu opioid receptor

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127953

N/A

0DataRank · unranked

8 citations

Huiqun Wang, James C. Gillespie, Rolando E. Mendez, Dana E. Selley, Yan Zhang +1 more

Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4,5α-epoxy-3,14β-dihydroxy-6β-[(4′-pyridyl) carboxamido]morphinan derivatives via their binding affinity and selectivity profiles on opioid receptors

Bioorganic Chemistry(2021)10.1016/j.bioorg.2021.104702

N/A

0DataRank · unranked

8 citations

Rama Gunta, Huiqun Wang, Mengchu Li, Danni Cao, Rolando E. Mendez +7 more

Teaching an old dog new tricks: Drug discovery by repositioning natural products and their derivatives

Drug Discovery Today(2022)10.1016/j.drudis.2022.02.007

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0DataRank · unranked

60 citations

Yan Zhang, Boshi Huang

Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00087

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0DataRank · unranked

20 citations

Mengchu Li, Yi Zheng, Abhishek S. Kulkarni, Samuel Obeng, Boshi Huang +10 more

Structural Alterations of the “Address” Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01499

N/A

0DataRank · unranked

12 citations

Piyusha P. Pagare, Mengchu Li, Logan T. Neel, Rolando E. Mendez, James C. Gillespie +5 more

Design of bivalent ligands targeting putative GPCR dimers

Drug Discovery Today(2020)10.1016/j.drudis.2020.10.006

N/A

0DataRank · unranked

49 citations

Celsey M. St. Onge, Hongguang Ma, Yan Zhang, Boshi Huang

Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation

Journal of Pharmaceutical and Biomedical Analysis(2022)10.1016/j.jpba.2022.115152

N/A

0DataRank · unranked

3 citations

Mohini S. Ghatge, Boshi Huang, Ahmed Abdullah Alghamdi, Huiqun Wang, B. Daniel Pierce +5 more

Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c02185

N/A

0DataRank · unranked

10 citations

Mengchu Li, Pornprom Klongkumnuankarn, Rolando E. Mendez, James C. Gillespie, David L. Stevens +4 more

Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers

Bioorganic Chemistry(2022)10.1016/j.bioorg.2022.105641

N/A

0DataRank · unranked

9 citations

Mengchu Li, Piyusha P. Pagare, Huiqun Wang, Nima Nassehi, Edna J. Santos +4 more

Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease

Biomolecules(2022)10.3390/biom12050696

N/A

0DataRank · unranked

7 citations

Mohini S. Ghatge, Akua K. Donkor, Tanvi Deshpande, Nancy Anabaraonye, Dina Alramadhani +7 more

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Molecules(2022)10.3390/molecules27206835

N/A

0DataRank · unranked

6 citations

Mohini S. Ghatge, Akua K. Donkor, Faik N. Musayev, Tanvi Deshpande, Mohammed A. AlAwadh +9 more

Elucidating the binding mechanism of LPA species and analogs in an LPA4 receptor homology model

Journal of Molecular Graphics and Modelling(2022)10.1016/j.jmgm.2022.108274

N/A

0DataRank · unranked

0 citations

Mengchu Li, Celsey M. St. Onge, Babette Fuss, Yan Zhang, Huiqun Wang

Merging cultures and disciplines to create a drug discovery ecosystem at Virginia commonwealth university: Medicinal chemistry, structural biology, molecular and behavioral pharmacology and computational chemistry

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.02.006

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0DataRank · unranked

4 citations

Yana Cen, Maƚgorzata Dukat, Keith C. Ellis, Youzhong Guo, Jiong Li +6 more

Novel PROTAC probes targeting FOSL1 degradation to eliminate head and neck squamous cell carcinoma cancer stem cells

Bioorganic Chemistry(2024)10.1016/j.bioorg.2024.107613

N/A

0DataRank · unranked

16 citations

Piyusha P. Pagare, Boshi Huang, Grace Rilee, Zhikun Ma, Yan Zhang +2 more

Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling

RSC Medicinal Chemistry(2024)10.1039/d4md00122b

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0DataRank · unranked

13 citations

Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong Li +1 more

NCP, a Dual Kappa and Mu Opioid Receptor Agonist, Is a Potent Analgesic Against Inflammatory Pain without Reinforcing or Aversive Properties

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.123.001870

N/A

0DataRank · unranked

9 citations

Conrad K. Ho, Danni Cao, Saadet Inan, Scott M. Rawls, Mengchu Li +9 more

Blocking potential metabolic sites on NAT to improve its safety profile while retaining the pharmacological profile

Bioorganic Chemistry(2024)10.1016/j.bioorg.2024.107489

N/A

0DataRank · unranked

0 citations

Boshi Huang, Piyusha P. Pagare, Celsey M. St. Onge, Abeje Abebayehu, James C. Gillespie +5 more

Exploring substitution effects on the potential dominant conformations of NBF derivatives leading to functional conversion at the mu opioid receptor

RSC Chemical Biology(2025)10.1039/d5cb00036j

N/A

0DataRank · unranked

0 citations

Ahmed Reda, Hongguang Ma, Samuel Woodard, James C. Gillespie, Dana E. Selley +4 more

Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion

Frontiers in Pharmacology(2022)10.3389/fphar.2022.835809

N/A

0DataRank · unranked

10 citations

Peng Huang, Kathryn Bland, Mengchu Li, Yan Zhang, Lee‐Yuan Liu‐Chen +1 more