Adrian R. Krainer

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer”.

Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1013

N/A

0.631DataRank · unranked

66 citations

Kuan‐Ting Lin, Mohammad Alinoor Rahman, Yuma Ishigami, Zhikai Wang, Mads A. Jensen +5 more

Specificity, synergy, and mechanisms of splice-modifying drugs

Nature Communications(2024)10.1038/s41467-024-46090-5

N/A

0.571DataRank · unranked

44 citations

Mandy S. Wong, Carlos Martí‐Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M. Hanson +4 more

Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA

Nucleic Acids Research(2021)10.1093/nar/gkab1280

N/A

0.477DataRank · unranked

23 citations

Kuan‐Ting Lin, Tao Jiang, Yang Yang, Mohammad Alinoor Rahman, Shuaishuai Gong +7 more

Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108559

N/A

0.227DataRank · unranked

3 citations

Xiaochun Yang, Taj Mohammad, Xiyan Xiang, Christine L. Sardo Molmenti, Bibhuti Mishra +6 more

Towards a combined therapy for spinal muscular atrophy based on opposing effects of an antisense oligonucleotide on chromatin and splicing

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.24.461646

N/A

0DataRank · unranked

0 citations

Gwendal Dujardin, Rui Sousa‐Luís, Ying Hsiu Liu, José N. Stigliano, Tomoki Nomakuchi +4 more

Loss of KRAS G12D feedback regulation involving splicing factor SRSF1 accelerates pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.13.464210

N/A

0DataRank · unranked

0 citations

Kuan‐Ting Lin, Mohammad Alinoor Rahman, Zhikai Wang, Mads A. Jensen, Youngkyu Park +3 more

Higher-order epistasis and phenotypic prediction

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204233119

N/A

0DataRank · unranked

55 citations

Mandy S. Wong, Wei-Chia Chen, Adrian R. Krainer, Justin B. Kinney, David M. McCandlish +1 more

Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy

Nature Communications(2022)10.1038/s41467-022-30668-y

N/A

0DataRank · unranked

41 citations

Tomoki Nomakuchi, Foteini Papaleonidopoulou, Lucia Yang, Qian Zhang, Adrian R. Krainer +1 more

Exon-skipping antisense oligonucleotides for cystic fibrosis therapy

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2114858118

N/A

0DataRank · unranked

39 citations

Nicole Sivetz, Jessica Layne, Dillon M. Voss, Lucia Yang, Qian Zhang +2 more

Antisense Oligonucleotide Therapeutics for Cystic Fibrosis: Recent Developments and Perspectives

Molecules and Cells(2023)10.14348/molcells.2023.2172

N/A

0DataRank · unranked

34 citations

Adrian R. Krainer, Young Jin Kim

Aldehydes alter TGF-β signaling and induce obesity and cancer

Cell Reports(2024)10.1016/j.celrep.2024.114676

N/A

0DataRank · unranked

17 citations

Krishanu Bhowmick, Shuyun Rao, Xiyan Xiang, Kazufumi Ohshiro, Richard Amdur +20 more

Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma

Nature Genetics(2024)10.1038/s41588-024-01790-y

N/A

0DataRank · unranked

15 citations

Patrick J. Cunniff, Allison C. Schier, Damianos Skopelitis, Marygrace C. Trousdell, Philip Moresco +15 more

SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2322974121

N/A

0DataRank · unranked

7 citations

Dexter W. Adams, Nickolas Hoffman, Polona Šafarič Tepeš, Tse-Luen Wee, Paolo Cifani +3 more

New insights into biomarkers and risk stratification to predict hepatocellular cancer

Molecular Medicine(2025)10.1186/s10020-025-01194-6

N/A

0DataRank · unranked

13 citations

Bino Mathew, Ethan Saldanha, Puja Ghosh, Adrian R. Krainer, Srinivasan Dasarathy +4 more

PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108345

N/A

0DataRank · unranked

7 citations

Alexander J. Kral, GeunYoung Sim, Raditya Utama, Kuan‐Ting Lin, Chris Cizmeciyan +7 more

Higher-order epistasis and phenotypic prediction

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.14.339804

N/A

0DataRank · unranked

1 citations

Mandy S. Wong, Wei-Chia Chen, Adrian R. Krainer, Justin B. Kinney, David M. McCandlish +1 more

Splice-switching ASOs targeting an Alu-derived exon in the AURKA 5’UTR collapse an SRSF1-AURKA-MYC oncogenic circuit in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.14.648775

N/A

0DataRank · unranked

0 citations

Jia Lu, GeunYoung Sim, Ledong Wan, Adrian R. Krainer, Alexander J. Kral

Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia

Nature Communications(2021)10.1038/s41467-021-24705-5

N/A

0DataRank · unranked

42 citations

Tomonari Awaya, Young Jin Kim, Kei Iida, Masatsugu Denawa, Nobuo Tanaka +7 more

Exon-Skipping Antisense Oligonucleotides for Cystic Fibrosis Therapy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.11.455936

N/A

0DataRank · unranked

12 citations

Nicole Sivetz, Jessica Layne, Dillon M. Voss, Lucia Yang, Qian Zhang +2 more

Gene-Specific Nonsense-Mediated mRNA Decay Targeting for Cystic Fibrosis Therapy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.13.452144

N/A

0DataRank · unranked

5 citations

Tomoki Nomakuchi, Foteini Papaleonidopoulou, Adrian R. Krainer, Young Jin Kim