Joaquı́n M. Espinosa

University of Colorado Anschutz Medical Campus

ORCID: 0000-0001-9048-1941

Social SciencesMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.4Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The COVIDome Explorer researcher portal

Cell Reports(2021)10.1016/j.celrep.2021.109527

Top 15%

1.4DataRank

Top 15%48 citations

Matthew D. Galbraith, Kohl T. Kinning, Kyle W. Bartsch, Nik Levinsky, Paula Araya +19 more

Papers

Driven by 50 papers — median percentile 85. Top paper: “The COVIDome Explorer researcher portal”.

The COVIDome Explorer researcher portal

Cell Reports(2021)10.1016/j.celrep.2021.109527

Top 15%

1.4DataRank

Top 15%48 citations

Matthew D. Galbraith, Kohl T. Kinning, Kyle W. Bartsch, Nik Levinsky, Paula Araya +19 more

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

Nature Genetics(2023)10.1038/s41588-023-01399-7

N/A

1.4DataRank · unranked

115 citations

Ross Minter, Jessica Baxter, Congwu Chi, Matthew D. Galbraith, Kathryn D. Tuttle +27 more

Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition

Science Advances(2023)10.1126/sciadv.adg6218

N/A

1.3DataRank · unranked

86 citations

Angela L. Rachubinski, Keith P. Smith, Paula Araya, Katherine A. Waugh, Belinda A Enriquez-Estrada +9 more

JAK inhibition decreases the autoimmune burden in Down syndrome

eLife(2024)10.7554/elife.99323

N/A

0.670DataRank · unranked

28 citations

Elizabeth Wallace, Emily Gurnee, Belinda A Enriquez Estrada, Kayleigh R Worek, Keith P. Smith +17 more

Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients as a function of therapeutic transfusion and hydroxyurea treatment

Haematologica(2023)10.3324/haematol.2023.283288

N/A

0.622DataRank · unranked

25 citations

Mehdi Nouraie, Yingze Zhang, Francesca Cendali, Fabia Gamboni, Julie A. Reisz +7 more

Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway

Cancer Research(2023)10.1158/0008-5472.can-22-3173

N/A

0.532DataRank · unranked

15 citations

Matthew D. Galbraith, Neetha Paul Eduthan, Amanda A. Hill, Michael R. Clay, Cristiam Moreno Tellez +5 more

Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30

Cell Reports(2020)10.1016/j.celrep.2020.03.011

N/A

0.529DataRank · unranked

33 citations

Sara Zaccara, Annalisa Rossi, Matthew D. Galbraith, Zdeněk Andrysík, Ahwan Pandey +6 more

PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

Nature Communications(2022)10.1038/s41467-022-35089-5

N/A

0.510DataRank · unranked

29 citations

Kelly D. Sullivan, Jeffrey Scott Kieft, Joaquı́n M. Espinosa, Zdeněk Andrysík

Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation

Cell Death and Differentiation(2023)10.1038/s41418-023-01113-4

N/A

0.457DataRank · unranked

20 citations

Micah G. Donovan, Matthew D. Galbraith, Huy Nguyen Duc, Maria M. Szwarc, Molishree Joshi +9 more

The history of Down syndrome–associated Alzheimer's disease; past, present, and future

Alzheimer s & Dementia(2025)10.1002/alz.70158

N/A

0.385DataRank · unranked

12 citations

María Carmona‐Iragui, Ira T. Lott, Elizabeth Head, Thomas Wisniewski, Michael S. Rafii +8 more

FAM193A is a positive regulator of p53 activity

Cell Reports(2023)10.1016/j.celrep.2023.112230

N/A

0.312DataRank · unranked

7 citations

Anna L. Guarnieri, Molishree Joshi, Huy Nguyen Duc, Madison C. Laird, Ahwan Pandey +8 more

Cardiopulmonary Phenotypes and Protein Signatures in Children With Down Syndrome

Clinical Pediatrics(2023)10.1177/00099228231179453

N/A

0.269DataRank · unranked

5 citations

Kristine Wolter‐Warmerdam, Robin R. Deterding, Juana Marmolejo, T Blumenthal, Joaquı́n M. Espinosa +3 more

Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients, as a function of therapeutic transfusion and hydroxyurea treatment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.05.535693

N/A

0.269DataRank · unranked

5 citations

Mehdi Nouraie, Yingze Zhang, Francesca Cendali, Fabia Gamboni, Julie A. Reisz +7 more

JAK inhibition decreases the autoimmune burden in Down syndrome

medRxiv(2024)10.1101/2024.06.13.24308783

N/A

0.208DataRank · unranked

3 citations

Elizabeth Wallace, Emily Gurnee, Belinda A Enriquez Estrada, Kayleigh R Worek, Keith P. Smith +17 more

Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs with Trisomy 21

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.19.465029

N/A

0.165DataRank · unranked

2 citations

Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia R. Shaw +5 more

Aberrant tissue mechanics and mechanotransduction during heart development in down syndrome

Journal of Biomechanics(2025)10.1016/j.jbiomech.2025.113103

N/A

0.165DataRank · unranked

2 citations

Mitchell C. VeDepo, Rukshika S. Hewawasam, Katherine A. Waugh, Kyndal A. Schade, Mostafa Abdel-Hafiz +7 more

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome

eLife(2024)10.7554/elife.100197

N/A

0.165DataRank · unranked

2 citations

Lynn Sanford, Samuel S. Hunter, Kayla Molison, Benjamin Erickson, Meaghan CS Courvan +9 more

Enhanced Effector Activity of Mediator Kinase Module Deficient CAR-T Cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.02.506235

N/A

0DataRank · unranked

0 citations

Julia A. Belk, Elena Sotillo, Bence Dániel, Katalin Sandor, Dorota D. Klysz +12 more

Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling

iScience(2023)10.1016/j.isci.2023.107012

N/A

0DataRank · unranked

30 citations

Walter E. Knight, Andrew S. Riching, Zhen Zhang, Roubina Tatavosian, Yonghua Zhuang +7 more

EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression

Neuro-Oncology(2023)10.1093/neuonc/noad128

N/A

0DataRank · unranked

11 citations

Melanie Y. Vincent, Taylor Hotz, Stephen C. Purdy, Sheera R. Rosenbaum, Connor J. Hughes +17 more

Plasma neurofilament light chain concentrations are elevated in youth‐onset type 2 diabetes and associated with neuropathy

Journal of the Peripheral Nervous System(2023)10.1111/jns.12575

N/A

0DataRank · unranked

12 citations

Stefan Sillau, Alanna Ritchie, Jacob Bockhorst, Christina Coughlan, Paula Araya +9 more

Severely ill and high-risk COVID-19 patients exhibit increased peripheral circulation of CD62L+ and perforin+ T cells

Frontiers in Immunology(2023)10.3389/fimmu.2023.1113932

N/A

0DataRank · unranked

7 citations

Paula Araya, Katherine A. Waugh, Lakshmi Chauhan, Joaquı́n M. Espinosa, J. David Beckham +1 more

Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection

iScience(2023)10.1016/j.isci.2023.107361

N/A

0DataRank · unranked

3 citations

Brian F. Niemeyer, Rocío J. Jiménez-Valdés, Alexander J. Kaiser, Joaquı́n M. Espinosa, Kelly D. Sullivan +7 more

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.05.547813

N/A

0DataRank · unranked

1 citations

Lynn Sanford, Samuel S. Hunter, Kayla Molison, Benjamin Erickson, Meaghan CS Courvan +9 more

Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome

Nature Communications(2024)10.1038/s41467-024-49781-1

N/A

0DataRank · unranked

25 citations

Neetha Paul Eduthan, Keith P. Smith, Eleanor Britton, Hannah R. Lyford, Paula Araya +8 more

Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome

Cell Reports(2024)10.1016/j.celrep.2024.114599

N/A

0DataRank · unranked

14 citations

Angela L. Rachubinski, Keith P. Smith, Paula Araya, Katherine A. Waugh, Belinda A Enriquez-Estrada +10 more

Addressing challenges in health care and research for people with Down syndrome

The Lancet(2024)10.1016/s0140-6736(24)00478-1

N/A

0DataRank · unranked

14 citations

Eimear McGlinchey, Joaquı́n M. Espinosa, Michael S. Rafii, Juan Fortea

Neuron loss in the brain starts in childhood, increases exponentially with age and is halted by GM-CSF treatment in Alzheimer’s disease

medRxiv(2024)10.1101/2024.07.14.24310223

N/A

0DataRank · unranked

4 citations

Christina Coughlan, Md. Mahiuddin Ahmed, Kavita Nair, Paula Araya, Matthew D. Galbraith +7 more

Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model

iScience(2025)10.1016/j.isci.2025.113130

N/A

0DataRank · unranked

3 citations

Brian F. Niemeyer, Kyndal A. Schade, Lauren N. Dunn, Katherine A. Waugh, Nicolas Busquet +11 more

Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer’s disease by GM-CSF treatment

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102525

N/A

0DataRank · unranked

1 citations

Christina Coughlan, Md. Mahiuddin Ahmed, Kavita Nair, Paula Araya, Matthew D. Galbraith +10 more

A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions

Frontiers in Systems Biology(2025)10.3389/fsysb.2024.1422384

N/A

0DataRank · unranked

3 citations

Masanori Aikawa, Hassan Ashktorab, Noam D. Beckmann, Michael L. Enger, Joaquı́n M. Espinosa +18 more

Altered Hepatic Metabolism in Down Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.27.656393

N/A

0DataRank · unranked

4 citations

Brian F. Niemeyer, Neetha Paul Eduthan, Kyndal A. Schade, Katherine A. Waugh, Chrisstopher Brown +7 more

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

Cell Reports(2020)10.1016/j.celrep.2020.108407

N/A

0DataRank · unranked

67 citations

Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael P. Ludwig +11 more

Elevated mitochondrial metabolism in Down syndrome iPSCs reduces commitment to neuroectoderm

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.09.653211

N/A

0DataRank · unranked

1 citations

Guilherme Henrique Souza Bomfim, Neil Jeju, Yingli Duan, Brian F. Niemeyer, Joaquı́n M. Espinosa +5 more

Tumoural soft tissue calcification in Down syndrome: association with heterozygous germline SAMD9 mutation and hyperactive type I interferon signaling

Lara D. Veeken(2020)10.1093/rheumatology/keaa301

N/A

0DataRank · unranked

2 citations

Julia R. Hirsiger, Marc B. Bigler, Adhideb Ghosh, Dorothee Harder, Annaïse Jauch +6 more

JAK1 inhibition blocks lethal sterile immune responses: implications for COVID-19 therapy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.07.024455

N/A

0DataRank · unranked

15 citations

Ross Minter, Katherine A. Waugh, Paula Araya, Michael P. Ludwig, Colin Sempeck +8 more

Seroconversion stages COVID19 into distinct pathophysiological states

medRxiv(2020)10.1101/2020.12.05.20244442

N/A

0DataRank · unranked

10 citations

Kohl T. Kinning, Kelly D. Sullivan, Ryan M. Baxter, Paula Araya, Kimberly R. Jordan +13 more

USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.01.181883

N/A

0DataRank · unranked

1 citations

Juliana Haydeé Enriqué Steinberg, Ezequiel Calvo-Roitberg, Molishree Joshi, Ahwan Pandey, Martı́n C. Abba +8 more

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p

UNC Libraries(2020)10.17615/dnrn-cx42

N/A

0DataRank · unranked

0 citations

Heide L. Ford, Austin E. Gillen, Carol A. Sartorius, Michelle A. Guney, Aik Choon Tan +7 more

Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response

Nature Communications(2021)10.1038/s41467-021-21687-2

N/A

0DataRank · unranked

64 citations

Heather Bender, Matthew D. Galbraith, Joaquı́n M. Espinosa, Zdeněk Andrysík

USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer

Oncogenesis(2021)10.1038/s41389-021-00318-x

N/A

0DataRank · unranked

24 citations

Juliana Haydeé Enriqué Steinberg, Ezequiel Calvo-Roitberg, Molishree Joshi, Ahwan Pandey, Martı́n C. Abba +8 more

HERC1 Regulates Breast Cancer Cells Migration and Invasion

Cancers(2021)10.3390/cancers13061309

N/A

0DataRank · unranked

15 citations

Ezequiel Calvo-Roitberg, Juliana Haydeé Enriqué Steinberg, Molishree Joshi, Joaquı́n M. Espinosa, Mario Rossi +1 more

The COVIDome Explorer Researcher Portal

medRxiv(2021)10.1101/2021.03.04.21252945

N/A

0DataRank · unranked

3 citations

Matthew D. Galbraith, Kohl T. Kinning, Kyle W. Bartsch, Nik Levinsky, Paula Araya +19 more

Specialized interferon ligand action in COVID19

medRxiv(2021)10.1101/2021.07.29.21261325

N/A

0DataRank · unranked

1 citations

Kohl T. Kinning, Kelly D. Sullivan, Paula Araya, Keith P. Smith, Ross E. Granrath +16 more

Trisomy 21 induces pericentrosomal crowding disrupting early stages of primary ciliogenesis and mouse cerebellar development

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.10.468107

N/A

0DataRank · unranked

0 citations

Bailey L McCurdy, Eileen O’Toole, Katherine S. Given, Carrie H. Lin, Valerie Olsen +8 more

Enhanced T cell effector activity by targeting the Mediator kinase module

Science(2022)10.1126/science.abn5647

N/A

0DataRank · unranked

147 citations

Julia A. Belk, Elena Sotillo, Patrick J. Quinn, María C. Ramello, Meena Malipatlolla +16 more

Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21

Frontiers in Cellular Neuroscience(2022)10.3389/fncel.2021.794675

N/A

0DataRank · unranked

27 citations

Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia R. Shaw +5 more

Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development

eLife(2022)10.7554/elife.78202

N/A

0DataRank · unranked

19 citations

Bailey L McCurdy, Eileen O’Toole, Alexander J. Stemm-Wolf, Katherine S. Given, Carrie H. Lin +9 more

Interferon receptor gene dosage determines diverse hallmarks of Down syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.03.478982

N/A

0DataRank · unranked

14 citations

Ross Minter, Jessica Baxter, Congwu Chi, Kathryn D. Tuttle, Neetha Paul Eduthan +26 more

Multi-Omics Assessment of Genetic Risk for Celiac Disease in Down Syndrome

medRxiv(2022)10.1101/2022.09.27.22280436

N/A

0DataRank · unranked

3 citations

Jessica R. Shaw, Neetha Paul Eduthan, Angela L. Rachubinski, Keith P. Smith, Belinda Enriquez Estrada +10 more

Joaquı́n M. Espinosa

Indexed papers

Top data-sharing exemplar

Papers