Kenneth A. Matreyek

Also affiliated with Case Western Reserve University

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.3Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers

Genome Medicine(2021)10.1186/s13073-021-00984-x

Top 16%

1.3DataRank

Top 16%52 citations

Jason J. Stephany, Ethan Ahler, Douglas M. Fowler, Kenneth A. Matreyek

Papers

Driven by 27 papers — median percentile 84. Top paper: “Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact”.

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

eLife(2020)10.7554/elife.58026

N/A

2.2DataRank · unranked

103 citations

Nathan Rollins, Jason J. Stephany, Katherine A. Sitko, Kenneth A. Matreyek, Marta Verby +7 more

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers

Genome Medicine(2021)10.1186/s13073-021-00984-x

Top 16%

1.3DataRank

Top 16%52 citations

Jason J. Stephany, Ethan Ahler, Douglas M. Fowler, Kenneth A. Matreyek

Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1915680117

N/A

0.743DataRank · unranked

141 citations

Takaya Moriyama, Kenneth A. Matreyek, Wentao Yang, Emma Rose Scaletti, Rina Nishii +27 more

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike

Nature Communications(2023)10.1038/s41467-023-37786-1

N/A

0.564DataRank · unranked

42 citations

Zongjun Mou, Ruipeng Lei, Wenhao O. Ouyang, Meng Yuan, Ge Song +7 more

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.123.001659

N/A

0.550DataRank · unranked

13 citations

Conor McClenaghan, Kenneth A. Matreyek, Dorothy K. Grange, Colin G. Nichols, Jian Gao

Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling

Nature Communications(2021)10.1038/s41467-021-27342-0

N/A

0.538DataRank · unranked

35 citations

David Nedrud, Antonio Suma, Yungui He, Kenneth A. Matreyek, Douglas M. Fowler +4 more

The biophysical basis of protein domain compatibility

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.09.418442

N/A

0.196DataRank · unranked

2 citations

David Nedrud, Antonio Suma, Yungui He, Kenneth A. Matreyek, Douglas M. Fowler +4 more

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.27.559757

N/A

0.104DataRank · unranked

1 citations

Abby Odle, Ruipeng Lei, Kenneth A. Matreyek, Stanley Perlman, Lok-Yin Roy Wong +2 more

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

PLoS Biology(2022)10.1371/journal.pbio.3001738

N/A

0DataRank · unranked

52 citations

Nidhi Shukla, Anh Pham, Anna Bruchez, Kenneth A. Matreyek, Sarah Roelle

Receptor binding domain (RBD) antibodies contribute more to SARS-CoV-2 neutralization when target cells express high levels of ACE2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.29.505713

N/A

0DataRank · unranked

14 citations

Bernadeta Dadonaite, Allison J. Greaney, Rachel Eguia, Andrea N. Loes, Nicholas Franko +7 more

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.24.509341

N/A

0DataRank · unranked

7 citations

Zongjun Mou, Ruipeng Lei, Wenhao O. Ouyang, Meng Yuan, Ge Song +7 more

Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.20.496903

N/A

0DataRank · unranked

4 citations

Timothy J.C. Tan, Ruipeng Lei, Ge Song, Collin Kieffer, Raiees Andrabi +3 more

Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants

ACS Synthetic Biology(2023)10.1021/acssynbio.3c00355

N/A

0DataRank · unranked

12 citations

Nisha D Kamath, Kenneth A. Matreyek, Sarah Roelle

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2317222121

N/A

0DataRank · unranked

17 citations

Abhishek Kumar Verma, Abby Odle, Ruipeng Lei, David K. Meyerholz, Kenneth A. Matreyek +4 more

Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage

PLoS Pathogens(2024)10.1371/journal.ppat.1012044

N/A

0DataRank · unranked

5 citations

Sarah Roelle, John Snell, Olivia DelSignore, Anna Bruchez, Kenneth A. Matreyek +1 more

The quantitative impact of 3′UTRs on gene expression

Nucleic Acids Research(2025)10.1093/nar/gkaf568

N/A

0DataRank · unranked

11 citations

H. Jesse Smith, Luyen Tien Vu, Elizabeth A. Fogarty, Kenneth A. Matreyek, Douglas M. Fowler +2 more

Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function

Genetics(2025)10.1093/genetics/iyaf146

N/A

0DataRank · unranked

4 citations

Kenneth A. Matreyek, Nisha D Kamath

Kozak sequence libraries for characterizing transgenes across expression levels

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.28.651141

N/A

0DataRank · unranked

5 citations

Nisha D Kamath, John Snell, Anna Bruchez, Kenneth A. Matreyek, Nidhi Shukla

Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.23.634525

N/A

0DataRank · unranked

0 citations

Kenneth A. Matreyek, Nisha D Kamath

DIALing in elevated expression setpoints with promoter shortening

Cell Systems(2025)10.1016/j.cels.2025.101482

N/A

0DataRank · unranked

0 citations

Brian J. Nelson, Kenneth A. Matreyek, John Snell

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1

Heart Rhythm(2020)10.1016/j.hrthm.2020.05.041

N/A

0DataRank · unranked

66 citations

Andrew M. Glazer, Chai‐Ann Ng, Daniel J. Blackwell, Christian Egly, Loren Vanags +9 more

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.10.087312

N/A

0DataRank · unranked

2 citations

Nathan Rollins, Jason J. Stephany, Katherine A. Sitko, Kenneth A. Matreyek, Marta Verby +7 more

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KCNH2 : Deep mutational scan of KCNH2 trafficking

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.17.952606

N/A

0DataRank · unranked

0 citations

Andrew M. Glazer, Chai-Ann Ng, Daniel Blackwell, Christian L. Egly, Loren R. Vanags +9 more

Extracellular vesicles carry SARS‐CoV‐2 spike protein and serve as decoys for neutralizing antibodies

Journal of Extracellular Vesicles(2021)10.1002/jev2.12112

N/A

0DataRank · unranked

90 citations

Najwa Alhusaini, Caroline O. Tabler, Thomas J. Sweet, Karina I. Carvalho, Daniela Schlatzer +5 more

Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

PLoS Pathogens(2021)10.1371/journal.ppat.1009715

N/A

0DataRank · unranked

37 citations

Sarah Roelle, Vinicius G. Suzart, Anna Bruchez, Kenneth A. Matreyek, Nidhi Shukla

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.25.474149

N/A

0DataRank · unranked

2 citations

Nidhi Shukla, Anh Pham, Anna Bruchez, Kenneth A. Matreyek, Sarah Roelle

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

Science(2022)10.1126/science.abo7896

N/A

0DataRank · unranked

341 citations

Allison J. Greaney, William W. Hannon, Andrea N. Loes, Kevin Hauser, Josh R. Dillen +10 more

Kenneth A. Matreyek

Indexed papers

Top data-sharing exemplar

Papers