Shengdar Q. Tsai

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells”.

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells

Blood(2021)10.1182/blood.2020008503

N/A

0.650DataRank · unranked

75 citations

Julie Brault, Ronald J. Meis, Siyuan Liu, Linhong Li, Mara Pavel-Dinu +18 more

High-fidelity PAMless base editing of hematopoietic stem cells to treat chronic granulomatous disease

Science Translational Medicine(2024)10.1126/scitranslmed.adj6779

N/A

0.585DataRank · unranked

23 citations

Linyuan Ma, Siyuan Liu, Lauren R. Fox, Madelynn N. Whittaker, Ronald J. Meis +15 more

Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease

Molecular Therapy(2024)10.1016/j.ymthe.2024.07.022

N/A

0.475DataRank · unranked

17 citations

Kiera O’Keefe, Yichao Li, Thiyagaraj Mayuranathan, Cícera R. Lazzarotto, Rachael K. Wood +22 more

Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.07.372748

N/A

0.416DataRank · unranked

15 citations

Qing Lyu, Amr R. Ghanam, Cícera R. Lazzarotto, Gregory A. Newby, Wei Zhang +13 more

Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice

Nature Biomedical Engineering(2025)10.1038/s41551-025-01499-1

N/A

0.342DataRank · unranked

8 citations

Sabyasachi Das, Vijai Krishnan, Leillani L. Ha, Lauren R. Fox, Hannah E. Stutzman +28 more

CRISPR-targetedMAGT1insertion restores XMEN patient hematopoietic stem cells and lymphocytes

Blood(2021)10.1182/blood.2021011192

N/A

0DataRank · unranked

38 citations

Taylor Liu, Ezekiel Bello, Siyuan Liu, Colin L. Sweeney, Ronald J. Meis +18 more

Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques

Molecular Therapy(2021)10.1016/j.ymthe.2021.06.016

N/A

0DataRank · unranked

21 citations

Cícera R. Lazzarotto, Shirley Chen, Tae–Hoon Shin, Stefan Cordes, Xing Fan +18 more

Human genetic diversity alters therapeutic gene editing off-target outcomes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.20.445054

N/A

0DataRank · unranked

5 citations

Jing Zeng, Linda Yingqi Lin, Manuel Tognon, My Anh Nguyen, Jiecong Lin +11 more

Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.06.455489

N/A

0DataRank · unranked

3 citations

Nicole J. Piscopo, Matthew H. Forsberg, Louise A. Saraspe, Amritava Das, Brittany Russell +9 more

Human genetic diversity alters off-target outcomes of therapeutic gene editing

Nature Genetics(2022)10.1038/s41588-022-01257-y

N/A

0DataRank · unranked

115 citations

Jing Zeng, Linda Yingqi Lin, Manuel Tognon, My Anh Nguyen, Jiecong Lin +11 more

Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2021-004446

N/A

0DataRank · unranked

63 citations

Nicole J. Piscopo, Matthew H. Forsberg, Louise A. Saraspe, Amritava Das, Brittany Russell +14 more

IFNA pathway drives the more aggressive phenotype of KRAS G12D -mutant pancreatic ductal adenocarcinomas via IFNAR1/STAT3 activation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.29.497540

N/A

0DataRank · unranked

0 citations

Daniel H. Schanne, Aya Matsui, Pin‐Ji Lei, Sebastian Klein, Shuichi Aoki +20 more

Potent and uniform fetal hemoglobin induction via base editing

Nature Genetics(2023)10.1038/s41588-023-01434-7

N/A

0DataRank · unranked

77 citations

Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Cícera R. Lazzarotto +22 more

Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy

Nature Biomedical Engineering(2023)10.1038/s41551-023-01132-z

N/A

0DataRank · unranked

43 citations

Leillani L. Ha, Rebecca Yaworski, Emma R Sutton, Cícera R. Lazzarotto, Kathleen A. Christie +10 more

CRISPR-Cas9-AAV versus lentivector transduction for genome modification of X-linked severe combined immunodeficiency hematopoietic stem cells

Frontiers in Immunology(2023)10.3389/fimmu.2022.1067417

N/A

0DataRank · unranked

26 citations

Taylor Liu, Siyuan Liu, Amanda Lawson, Uimook Choi, Nikita Kozhushko +16 more

Trichostatin A for Efficient CRISPR-Cas9 Gene Editing of Human Pluripotent Stem Cells

The CRISPR Journal(2023)10.1089/crispr.2023.0033

N/A

0DataRank · unranked

7 citations

Namita Khajanchi, Cícera R. Lazzarotto, Shengdar Q. Tsai, Krishanu Saha, Kaivalya Molugu

Base editing as a genetic treatment for spinal muscular atrophy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.20.524978

N/A

0DataRank · unranked

19 citations

Leillani L. Ha, Rebecca Yaworski, Cícera R. Lazzarotto, Kathleen A. Christie, Aoife Reilly +9 more

BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate

Cell stem cell(2024)10.1016/j.stem.2024.10.014

N/A

0DataRank · unranked

16 citations

Jing Zeng, Rahul Palchaudhuri, Chuanfeng Wu, Diana M. Abraham, Taha Bartu Hayal +36 more

Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.14.580371

N/A

0DataRank · unranked

0 citations

Isabella Zingler-Hoslet, Lei Shi, Varun Katta, Brittany E. Russell, Shengdar Q. Tsai +3 more

Virus-free CRISPR knockin of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells

Molecular Therapy(2025)10.1016/j.ymthe.2025.01.024

N/A

0DataRank · unranked

17 citations

Isabelle Zingler-Hoslet, Diana M. Tabima, Seth Zima, Lei Shi, Kirstan Gimse +11 more

GenomePAM directs PAM characterization and engineering of CRISPR-Cas nucleases using mammalian genome repeats

Nature Biomedical Engineering(2025)10.1038/s41551-025-01464-y

N/A

0DataRank · unranked

2 citations

Limei Ai, Bang Wang, Shifeng Lian, Lawrence Ip, James Liu +5 more

Brain-wide Genome Editing via STEP-RNPs for Treatment of Angelman Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.13.684643

N/A

0DataRank · unranked

1 citations

Ying Xie, Youmei Bao, Jiang Yu, Zefeng Wang, Jiali Fan +19 more

Safe and efficient peripheral blood stem cell collection in patients with sickle cell disease using plerixafor

Haematologica(2020)10.3324/haematol.2019.236182

N/A

0DataRank · unranked

60 citations

Alexis Leonard, David F. Stroncek, Sandhya R. Panch, Kamille A. West, Eoghan Molloy +12 more

GenomePAM directs PAM characterization and engineering of CRISPR-Cas nucleases using mammalian genome repeats

Research Square(2025)10.21203/rs.3.rs-4552906/v1

N/A

0DataRank · unranked

0 citations

Miao Yu, Limei Ai, Bang Wang, Shifeng Lian, James Liu +5 more

Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.05.186858

N/A

0DataRank · unranked

1 citations

Cícera R. Lazzarotto, Shirley Chen, Tae–Hoon Shin, Stefan Cordes, Isabel Jabara +16 more

The NIH Somatic Cell Genome Editing program

Nature(2021)10.1038/s41586-021-03191-1

N/A

0DataRank · unranked

132 citations

Erik J. Sontheimer, Philip J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu +70 more

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

Genome biology(2021)10.1186/s13059-021-02304-3

N/A

0DataRank · unranked

99 citations

Qing Lyu, Amr R. Ghanam, Cícera R. Lazzarotto, Gregory A. Newby, Wei Zhang +13 more

Easy-Prime: a machine learning–based prime editor design tool

Genome biology(2021)10.1186/s13059-021-02458-0

N/A

0DataRank · unranked

63 citations

Jingjing Chen, Shengdar Q. Tsai, Yong Cheng, Yichao Li