Alejandro Barrera

Also affiliated with Duke University Hospital, Applied Genetic Technologies (United States), Genetic Technologies (Australia), Pratt Institute

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.3Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multicenter integrated analysis of noncoding CRISPRi screens

Nature Methods(2024)10.1038/s41592-024-02216-7

Top 20%

1.0DataRank

Top 20%54 citations

Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis +29 more

Papers

Driven by 29 papers — median percentile 61. Top paper: “Deciphering the impact of genomic variation on function”.

Deciphering the impact of genomic variation on function

Nature(2024)10.1038/s41586-024-07510-0

N/A

1.1DataRank · unranked

89 citations

Jesse M. Engreitz, Heather A. Lawson, Harinder Singh, Lea M. Starita, Gary C. Hon +95 more

Multicenter integrated analysis of noncoding CRISPRi screens

Nature Methods(2024)10.1038/s41592-024-02216-7

Top 20%

1.0DataRank

Top 20%54 citations

Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis +29 more

Comprehensive evaluation of diverse massively parallel reporter assays to functionally characterize human enhancers genome-wide

Genome biology(2025)10.1186/s13059-025-03828-8

Top 59%

0.257DataRank

Top 59%4 citations

Alden King-Yung Leung, Yutong Zhu, Li Yao, Avery Willis, Xiuqi Pan +10 more

AP-1 subunits converge promiscuously at enhancers to potentiate transcription

Genome Research(2021)10.1101/gr.267898.120

N/A

0DataRank · unranked

45 citations

D. Dewran Koçak, Luke C. Bartelt, Courtney Williams, Alejandro Barrera, Charles A. Gersbach +2 more

Correcting signal biases and detecting regulatory elements in STARR-seq data

Genome Research(2021)10.1101/gr.269209.120

N/A

0DataRank · unranked

22 citations

Graham D. Johnson, Jungkyun Seo, Alejandro Barrera, Thomas Cowart, William H. Majoros +4 more

Genome-wide annotation of gene regulatory elements linked to cell fitness

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.08.434470

N/A

0DataRank · unranked

14 citations

Tyler S. Klann, Alejandro Barrera, Adarsh R. Ettyreddy, Siyan Liu, Ryan Rickels +10 more

Cooperative regulation of coupled oncoprotein translation and stability in triple-negative breast cancer by EGFR and CDK12

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.03.433762

N/A

0DataRank · unranked

3 citations

Natalia Sutiman, Xinyue Deng, Luke C. Bartelt, Qiang Chen, Alejandro Barrera +7 more

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.08.434430

N/A

0DataRank · unranked

3 citations

Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu +18 more

Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS -Mutant Cancers

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.17.508384

N/A

0DataRank · unranked

1 citations

Colin A. Martz, Andrew M. Waters, Alejandro Barrera, Justine C. Rutter, Christian Cerda-Smith +14 more

Glucocorticoid Receptor Regulated KCNA5 Mediates Cell Proliferation in Human Fetal Membranes

Research Square(2022)10.21203/rs.3.rs-1594481/v1

N/A

0DataRank · unranked

0 citations

Alejandro Barrera, Laavanya Sankaranarayanan, Terrence K. Allen, Timothy E. Reddy, Sarah J. Cunningham

Glucocorticoid Receptor Regulated KCNA5 Mediates Cell Proliferation in Human Fetal Membranes

Research Square(2022)10.21203/rs.3.rs-1594481/v2

N/A

0DataRank · unranked

0 citations

Alejandro Barrera, Laavanya Sankaranarayanan, Terrence K. Allen, Timothy E. Reddy, Sarah J. Cunningham

Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens

Nature Genetics(2023)10.1038/s41588-023-01554-0

N/A

0DataRank · unranked

81 citations

Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka +9 more

Integrin α3 promotes T H 17 cell polarization and extravasation during autoimmune neuroinflammation

Science Immunology(2023)10.1126/sciimmunol.adg7597

N/A

0DataRank · unranked

22 citations

William E. Barclay, Alejandro Barrera, Tzu-Chieh Liao, Harmony R. Salzler, Timothy E. Reddy +3 more

Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221448120

N/A

0DataRank · unranked

16 citations

Natalia Sutiman, Xinyue Deng, Annie Liu, Christian Cerda-Smith, Haley M. Hutchinson +11 more

Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.01.538906

N/A

0DataRank · unranked

8 citations

Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka +7 more

Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers

Research Square(2023)10.21203/rs.3.rs-3511242/v1

N/A

0DataRank · unranked

0 citations

Daniel P. Nussbaum, Colin A. Martz, Andrew M. Waters, Alejandro Barrera, Justine C. Rutter +13 more

Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers

npj Precision Oncology(2024)10.1038/s41698-024-00615-9

N/A

0DataRank · unranked

6 citations

Colin A. Martz, Andrew M. Waters, Alejandro Barrera, Annie Liu, Justine C. Rutter +15 more

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.10.574997

N/A

0DataRank · unranked

6 citations

Lexi R. Bounds, Carson Key Taylor, Alan L Su, Anthony Rizzo, Alejandro Barrera +4 more

Machine learning methods for predicting guide RNA effects in CRISPR epigenome editing experiments

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.18.590188

N/A

0DataRank · unranked

5 citations

Tianyou Luo, Alejandro Barrera, Lexi R. Bounds, Tyler S. Klann, Maria ter Weele +7 more

Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583177

N/A

0DataRank · unranked

3 citations

Joshua B. Black, Sean R. McCutcheon, Alejandro Barrera, Daniel J. Morone, Xander Nuttle +6 more

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.04.611293

N/A

0DataRank · unranked

2 citations

Marisa C. Hamilton, Thomas Cowart, Alejandro Barrera, Lexi R. Bounds, Alexander C. Nelson +6 more

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Science(2025)10.1126/science.adl1988

N/A

0DataRank · unranked

19 citations

Lexi R. Bounds, Carson Key Taylor, Alan L Su, Anthony Rizzo, Alejandro Barrera +12 more

Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editing

Cell Genomics(2025)10.1016/j.xgen.2025.100770

N/A

0DataRank · unranked

17 citations

Joshua B. Black, Sean R. McCutcheon, Alejandro Barrera, Shanté S. Berry, Daniel J. Morone +7 more

Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production

Nature Communications(2025)10.1038/s41467-025-62884-7

N/A

0DataRank · unranked

8 citations

Kelly Brewer, Shauna Morrow, Graham D. Johnson, Alejandro Barrera, Revathy Venukuttan +4 more

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER

Cell Genomics(2025)10.1016/j.xgen.2025.100766

N/A

0DataRank · unranked

6 citations

Marisa C. Hamilton, Thomas Cowart, Alejandro Barrera, Lexi R. Bounds, Alexander C. Nelson +8 more

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Cell Reports(2020)10.1016/j.celrep.2020.108460

N/A

0DataRank · unranked

75 citations

Sean R. McCutcheon, Shataakshi Dube, Alejandro Barrera, Tyler S. Klann, Grayson Rice +5 more

SMARCA2 is an essential and potent cofactor for a specific subset of the glucocorticoid response in A549 cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.13.688306

N/A

0DataRank · unranked

1 citations

D. Dewran Koçak, Keith Siklenka, Graham D. Johnson, Courtney Williams, Luke C. Bartelt +6 more

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

Nature Methods(2021)10.1038/s41592-021-01207-2

N/A

0DataRank · unranked

139 citations

Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu +18 more

Causal network inference from gene transcriptional time-series response to glucocorticoids

PLoS Computational Biology(2021)10.1371/journal.pcbi.1008223

N/A

0DataRank · unranked

38 citations

Bianca Dumitrascu, Ian C. McDowell, Brian Jo, Alejandro Barrera, Linda K. Hong +4 more

Alejandro Barrera

Indexed papers

Top data-sharing exemplar

Papers