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Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Science(2025)10.1126/science.adl1988Source: DataRank Database

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness is a research paper published in Science (2025). On theSindex it has a DataRank of 0. It has been cited 19 times.

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Open Access19 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 8.15)OA: greenTopics (29)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Lexi R. Bounds ORCID,Carson Key Taylor ORCID,Alan L Su ORCID,Anthony Rizzo ORCID,Alejandro Barrera ORCID

Live enrichment

PubMed:40997217 PMC:PMC13005951 OpenAlex:https://openalex.org/W4414500310

National Science Foundation

Grant: EFMA-1830957

National Institutes of Health

Grant: UM1HG009428

National Institutes of Health

Grant: UM1HG012053

National Institutes of Health

Grant: U01AI146356

National Institutes of Health

Grant: RM1HG011123

National Institutes of Health

Grant: R35GM156302

National Institutes of Health

Grant: R01MH125236

National Institutes of Health

Grant: R01HL146557

National Institutes of Health

Grant: R01HL160939

National Institutes of Health

Grant: T32HL160494

National Institutes of Health

Grant: R01HL153375

FWCI

8.15

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: https://www.science.org/content/page/science-licenses-journal-article-reuse

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13005951/

publisherhttps://www.science.org/doi/pdf/10.1126/science.adl1988

journalhttps://doi.org/10.1126/science.adl1988

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40997217

Fields of Study

RNA Research and SplicingRNA regulation and diseaseCellular Mechanics and Interactions

MeSH Terms

A549 CellsGene EditingEpigenomeCell AdhesionCell MovementEnhancer Elements, GeneticExtracellular MatrixFibroblastsHumansLungApoptosisMechanotransduction, CellularEpigenesis, GeneticCell ProliferationSingle-Cell AnalysisPrimary Cell CultureCRISPR-Cas Systems

Keywords

EpigeneticsEpigenomeEnhancerMechanosensitive channelsCRISPRExtracellular matrixPhenotypeEpigenomicsMechanotransduction