Ernest Fraenkel

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

20.0Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Transcriptional regulatory code of a eukaryotic genome

Nature(2004)10.1038/nature02800

Top 1%

10.6DataRank

Top 1%2201 citations

D. Benjamin Gordon, Tong Ihn Lee, Nicola J. Rinaldi, Kenzie D. Macisaac, Timothy W. Danford +21 more

Papers

Driven by 36 papers — median percentile 89. Top paper: “Transcriptional regulatory code of a eukaryotic genome”.

Transcriptional regulatory code of a eukaryotic genome

Nature(2004)10.1038/nature02800

Top 1%

10.6DataRank

Top 1%2201 citations

D. Benjamin Gordon, Tong Ihn Lee, Nicola J. Rinaldi, Kenzie D. Macisaac, Timothy W. Danford +21 more

Dictionary of immune responses to cytokines at single-cell resolution

Nature(2023)10.1038/s41586-023-06816-9

Top 6%

3.8DataRank

Top 6%349 citations

Teddy Huang, Shuqiang Li, Aileen Ma, Jorge L. Pérez, Chris Sander +5 more

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines

Nature Neuroscience(2022)10.1038/s41593-021-01006-0

Top 7%

3.1DataRank

Top 7%159 citations

Terri G. Thompson, Jonathan Li, Julia Kaye, Ryan G. Lim, Jie Wu +95 more

Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

Nature Genetics(2021)10.1038/s41588-021-00889-w

N/A

2.5DataRank · unranked

98 citations

Emily Lowry, Nicky A. Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris Mader +26 more

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Neuron(2023)10.1016/j.neuron.2023.01.010

Top 11%

1.8DataRank

Top 11%90 citations

Ryan G. Lim, Jie Wu, Aaron P. Frank, Loren Ornelas, Lindsay Panther +20 more

Tissue-specific transcriptional regulation has diverged significantly between human and mouse

Nature Genetics(2007)10.1038/ng2047

N/A

0.940DataRank · unranked

526 citations

Robin D. Dowell, Elizabeth S Jacobsen, William Gordon, Timothy W. Danford, Kenzie D. Macisaac +7 more

A framework for sharing of clinical and genetic data for precision medicine applications

Nature Medicine(2024)10.1038/s41591-024-03239-5

N/A

0.857DataRank · unranked

32 citations

Ulugbek K. Baymuradov, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach +63 more

Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Nature Genetics(2023)10.1038/s41588-023-01551-3

N/A

0.631DataRank · unranked

66 citations

Jens Luebeck, Sunita Sridhar, Ivy Tsz-Lo Wong, Deobrat Dixit, Shanqing Wang +43 more

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02050-w

N/A

0.593DataRank · unranked

23 citations

Anna‐Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi +94 more

An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration

Nature Communications(2025)10.1038/s41467-025-59654-w

N/A

0.464DataRank · unranked

21 citations

Camila A. Zanella, Byunguk Kang, Jiajie Peng, David Gritsch, Zhixiang Liao +13 more

NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency

Scientific Data(2023)10.1038/s41597-022-01687-7

Top 44%

0.427DataRank

Top 44%11 citations

Vineet Vaibhav, Ronald J. Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo +32 more

An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.17.585262

N/A

0.269DataRank · unranked

5 citations

Camila A. Zanella, Byunguk Kang, Jiajie Peng, David Gritsch, Zhixiang Liao +13 more

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Neuron(2025)10.1016/j.neuron.2025.05.022

Top 70%

0.165DataRank

Top 70%2 citations

Ryan G. Lim, Jie Wu, Aaron P. Frank, Loren Ornelas, Lindsay Panther +20 more

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100947

Top 78%

0.104DataRank

Top 78%1 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +69 more

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Nature Communications(2022)10.1038/s41467-022-35388-x

N/A

0DataRank · unranked

80 citations

Osama Al‐Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang +24 more

Single cell metabolism: current and future trends

Metabolomics(2022)10.1007/s11306-022-01934-3

N/A

0DataRank · unranked

60 citations

Shawn M. Davidson, Ernest Fraenkel, Ian S. Gilmore, Thomas Hankemeier, Jennifer Kirwan +8 more

Single nuclei RNAseq analysis of HD mouse models and human brain reveals impaired oligodendrocyte maturation and potential role for thiamine metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.27.497613

N/A

0DataRank · unranked

2 citations

Osama Al‐Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang +23 more

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation

Stem Cell Reports(2020)10.1016/j.stemcr.2020.01.015

N/A

0DataRank · unranked

80 citations

Sarah Hernandez, Ryan G. Lim, Miriam Adam, Jie Wu, Jennifer Stocksdale +12 more

Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco phenotyping in patients with gliomas

Science Translational Medicine(2023)10.1126/scitranslmed.adi0069

N/A

0DataRank · unranked

22 citations

Christine Dominas, Geoffrey Fell, Joshua D. Bernstock, Sarah E. Blitz, Debora Mazzetti +18 more

Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

Nature Communications(2023)10.1038/s41467-023-42822-1

N/A

0DataRank · unranked

12 citations

Hassan Bukhari, Matthew Leventhal, Rachel A. Battaglia, Xianjun Dong, Ernest Fraenkel +2 more

Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.06.560646

N/A

0DataRank · unranked

1 citations

Hassan Bukhari, Matthew Leventhal, Rachel A. Battaglia, Xianjun Dong, Ernest Fraenkel +2 more

Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-2975

N/A

0DataRank · unranked

35 citations

Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Héraud, Albert Grinshpun +26 more

Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma

Cancer Letters(2024)10.1016/j.canlet.2024.217265

N/A

0DataRank · unranked

8 citations

Mona Göttmann, Maxwell P. Gold, Silja Schlue, Thomas Hielscher, Murat Iskar +18 more

Listener effort measures clinically meaningful change of dysarthria in amyotrophic lateral sclerosis

Brain Communications(2025)10.1093/braincomms/fcaf232

N/A

0DataRank · unranked

3 citations

Raquel Norel, Esteban G. Roitberg, Julián Peller, Marcos A. Trevisan, Carla Agurto +14 more

Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons

Neurobiology of Disease(2025)10.1016/j.nbd.2025.106914

N/A

0DataRank · unranked

4 citations

Matthew Leventhal, Stephanie Lam, Yuxin Xu, Yi Wang, Keona Q. Wang +26 more

Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.29.679403

N/A

0DataRank · unranked

2 citations

Zhengde Liu, Keyana Blake, Yue Qi, Sasha Rollinson, Sahba Seddighi +13 more

Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

npj Parkinson s Disease(2020)10.1038/s41531-020-00143-w

N/A

0DataRank · unranked

33 citations

Michael Murphy, Eric B. Dammer, Abby L. Olsen, Srikant Rangaraju, Ernest Fraenkel +2 more

Corrigendum to “Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data”

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100995

N/A

0DataRank · unranked

0 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +68 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.01.362269

N/A

0DataRank · unranked

3 citations

Emilda Gomez, Lindsay Panther, Aaron P. Frank, Susan Lei, Berhan Mandefro +40 more

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

Scientific Reports(2020)10.1038/s41598-020-61142-8

N/A

0DataRank · unranked

61 citations

Delfina Larrea, Marta Pera, Rishi R. Agrawal, David N. Guilfoyle, Leila Pirhaji +12 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

iScience(2021)10.1016/j.isci.2021.103221

N/A

0DataRank · unranked

51 citations

Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono +92 more

Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics

Human Molecular Genetics(2021)10.1093/hmg/ddab200

N/A

0DataRank · unranked

18 citations

Mali Jiang, Amanda J. Kedaigle, Nicolas Arbez, Leonard O. Marque, Chelsy R. Eddings +12 more

Phenotyping Neurodegeneration in Human iPSCs

Annual Review of Biomedical Data Science(2021)10.1146/annurev-biodatasci-092820-025214

N/A

0DataRank · unranked

10 citations

Ernest Fraenkel, Jonathan Li

The landscape of extrachromosomal circular DNA in medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.18.464907

N/A

0DataRank · unranked

13 citations

Jens Luebeck, Sameena Wani, Ashutosh Tiwari, Meghana S. Pagadala, Shanqing Wang +26 more

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature(2022)10.1038/s41586-022-04436-3

N/A

0DataRank · unranked

525 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +90 more

A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules

Scientific Reports(2020)10.1038/s41598-020-57691-7

N/A

0DataRank · unranked

78 citations

Miriam Adam, Nhan Huynh, Brook T. Wassie, Pamela Milani, Ernest Fraenkel +1 more

Ernest Fraenkel

Indexed papers

Top data-sharing exemplar

Papers