Costas A. Lyssiotis

Also affiliated with Michigan Medicine, Ann Arbor Center for Independent Living

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 114 papers. Top paper: “GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis”.

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Nature Communications(2021)10.1038/s41467-021-24859-2

N/A

6.7DataRank · unranked

258 citations

Barbara Scott Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk +29 more

Arginase 1 is a key driver of immune suppression in pancreatic cancer

eLife(2023)10.7554/elife.80721

N/A

2.9DataRank · unranked

157 citations

Zeribe C. Nwosu, Wenting Du, Katelyn L. Donahue, Hanna S. Hong, Carlos E. Espinoza +15 more

Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

Cell Host & Microbe(2024)10.1016/j.chom.2024.03.001

N/A

1.4DataRank · unranked

65 citations

Marie Boudaud, Mathis Wolter, Celeste Alexander, Alessandro De Sciscio, Erica T. Grant +20 more

Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis

Scientific Reports(2020)10.1038/s41598-020-59999-w

N/A

1.3DataRank · unranked

44 citations

Mercy Pawar, Eric Weh, Andrew D. Smith, Peter Sajjakulnukit, Li Zhang +6 more

Cysteine depletion induces pancreatic tumor ferroptosis in mice

Science(2020)10.1126/science.aaw9872

N/A

1.1DataRank · unranked

1221 citations

Daniel M. Kremer, H. Carlo Maurer, Kathleen E. DelGiorno, Ho‐Joon Lee, Vinee Purohit +25 more

Cancer SLC43A2 alters T cell methionine metabolism and histone methylation

Nature(2020)10.1038/s41586-020-2682-1

N/A

0.969DataRank · unranked

637 citations

Wei Li, Daniel M. Kremer, Peter Sajjakulnukit, Shasha Li, Joel Crespo +24 more

Fatty acid synthesis is required for breast cancer brain metastasis

Nature Cancer(2021)10.1038/s43018-021-00183-y

N/A

0.869DataRank · unranked

327 citations

Ahmed Ali, Alba Luengo, David P. Kodack, Amy Deik, Keene L. Abbott +31 more

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

Cancer Cell(2021)10.1016/j.ccell.2021.12.001

N/A

0.852DataRank · unranked

292 citations

Ryan J. Rebernick, Joshua Goyert, Rashi Singhal, Miljan Kuljanin, Samuel A. Kerk +12 more

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

Nature Communications(2020)10.1038/s41467-020-17512-x

N/A

0.835DataRank · unranked

261 citations

Yangyang Yao, Andrew J. Scott, Kari Wilder-Romans, Joseph Dresser, Christian K. Werner +23 more

GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity

Nature Cancer(2023)10.1038/s43018-023-00556-5

N/A

0.814DataRank · unranked

226 citations

Defne Bayık, Simon Storevik, Shannon Sherwin Moreino, Samuel A. Sprowls, Jianhua Han +37 more

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0131

N/A

0.757DataRank · unranked

155 citations

Abed Rahman Kawakibi, Sunjong Ji, Sebastian M. Waszak, Stefan R. Sweha, Mateus Mota +79 more

OXPHOS promotes apoptotic resistance and cellular persistence in T H 17 cells in the periphery and tumor microenvironment

Science Immunology(2022)10.1126/sciimmunol.abm8182

N/A

0.710DataRank · unranked

113 citations

Nneka E. Mbah, Mengrou Shan, Kristen Loesel, Lin Lin, Peter Sajjakulnukit +20 more

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

Nature Cancer(2022)10.1038/s43018-022-00393-y

N/A

0.670DataRank · unranked

86 citations

Joel Cassel, Farheen S. Mohammed, Mehrdad Zarei, Jonathan J. Hue, Omid Hajihassani +29 more

Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection

Gut Microbes(2022)10.1080/19490976.2022.2105609

N/A

0.604DataRank · unranked

55 citations

Katherine Z. Sanidad, Serena Lucotti, Carolin M. Lieber, Robert M. Cox, Aparna Ananthanarayanan +21 more

NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Cancer Research Communications(2022)10.1158/2767-9764.crc-21-0147

N/A

0.550DataRank · unranked

38 citations

Ralph Francescone, Janusz Franco‐Barraza, Jaye C. Gardiner, Débora B. Vendramini‐Costa, Tiffany Luong +10 more

GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms

Blood Cancer Journal(2022)10.1038/s41408-022-00745-y

N/A

0.533DataRank · unranked

34 citations

Chenguang Wang, Xin Gao, Pinki Chowdhury, J. Weiss, José A. Villegas +31 more

EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0679

N/A

0.490DataRank · unranked

14 citations

April A. Apfelbaum, Allegra G. Hawkins, Laurie K. Svoboda, Abhijay Kumar, Ramón Ocádiz-Ruiz +11 more

Cyst fluid metabolites distinguish malignant from benign pancreatic cysts

Neoplasia(2021)10.1016/j.neo.2021.09.004

N/A

0.396DataRank · unranked

13 citations

Zhujun Yi, Lin Jin, Lili Zhao, Alexander Raskind, Larisa Yeomans +6 more

Gut sulfide metabolism modulates behavior and brain bioenergetics

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2503677122

N/A

0.360DataRank · unranked

10 citations

Delawrence J. Sykes, Victor I. Band, Megan L. Schaller, Romel Patel, Victor Vitvitsky +9 more

Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma

Neoplasia(2023)10.1016/j.neo.2023.100931

N/A

0.360DataRank · unranked

10 citations

Ivana Barravecchia, Brian Magnuson, Sarah F. Ferris, April A. Apfelbaum, Nneka E. Mbah +9 more

Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.25.493422

N/A

0.345DataRank · unranked

9 citations

Amanda K. Huber, Rashi Singhal, Ryan J. Rebernick, Roshan Kumar, Nupur K. Das +17 more

BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.02.578646

N/A

0.269DataRank · unranked

5 citations

Drew Stark, Pankaj Jadhav, Theophilus Nguyen, Benjamin Halligan, Nicholas J. Rossiter +25 more

Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.29.582768

N/A

0.241DataRank · unranked

4 citations

Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan +23 more

De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.15.549149

N/A

0.124DataRank · unranked

1 citations

Raquel Buj, Hui Wang, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja +11 more

NetrinG1 + cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.21.469456

N/A

0.104DataRank · unranked

1 citations

Ralph Francescone, Janusz Franco‐Barraza, Jaye C. Gardiner, Débora B. Vendramini‐Costa, Tiffany Luong +9 more

GTP signaling links metabolism, DNA repair, and responses to genotoxic stress

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.12.536297

N/A

0.104DataRank · unranked

1 citations

Zitong Zhao, Angelica Lin, John Xun Yang, Jie Xu, Wilder-Romans Kari +30 more

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

Journal of Clinical Investigation(2021)10.1172/jci138926

N/A

0DataRank · unranked

46 citations

Lauren Bringman-Rodenbarger, Angela H. Guo, Surinder Kumar, Alexander C. Monovich, Ahmed M. Mostafa +32 more

Nutrient profiling reveals extracellular uridine as a fuel for pancreatic cancer through uridine phosphorylase 1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.07.447448

N/A

0DataRank · unranked

5 citations

Zeribe C. Nwosu, Pawan Poudel, Steven Kasperek, Zach Tolstyka, Rosa E. Menjivar +10 more

Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.26.457660

N/A

0DataRank · unranked

3 citations

Katelyn L. Donahue, Kristee Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar +18 more

Glutamine metabolism enables NKT cell homeostasis and function through the AMPK-mTORC1 signaling axis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.07.463490

N/A

0DataRank · unranked

3 citations

Emily L. Yarosz, Anthony Andren, Li Zhang, Costas A. Lyssiotis, Cheong‐Hee Chang +1 more

Multi-omic Characterization of Pancreatic Cancer-Associated Macrophage Polarization Reveals Deregulated Metabolic Programs Driven by the GMCSF-PI3K Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.10.459752

N/A

0DataRank · unranked

2 citations

Ho‐Joon Lee, Nina G. Steele, Li Zhang, Peter Sajjakulnukit, Anthony Andren +8 more

Multi-dimensional analyses identify genes of high priority for pancreatic cancer research

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.28.446056

N/A

0DataRank · unranked

1 citations

Heather Giza, Maya Nassif, Verodia Charlestin, Rosa E. Menjivar, Daeho Kim +8 more

A redox cycle with complex II promotes sulfide quinone oxidoreductase dependent H 2 S oxidation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.08.459449

N/A

0DataRank · unranked

1 citations

Aaron P. Landry, Arkajit Guha, Victor Vitvitsky, Ho‐Joon Lee, Keisuke Seike +4 more

Human norovirus infection of primary B cells triggers immune activation in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.14.444272

N/A

0DataRank · unranked

0 citations

Melissa K. Jones, Vivienne L. Young, Abimbola O. Kolawole, Irene A. Owusu, Mengrou Shan +8 more

OXPHOS Promotes Apoptotic Resistance and Persistence in T H 17 cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.01.462812

N/A

0DataRank · unranked

0 citations

Nneka E. Mbah, Mengrou Shan, Kristen Loesel, Lin Lin, Peter Sajjakulnukit +15 more

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

Cell Metabolism(2022)10.1016/j.cmet.2022.11.013

N/A

0DataRank · unranked

176 citations

Amanda K. Huber, Rashi Singhal, Navyateja Korimerla, Ryan J. Rebernick, Roshan Kumar +21 more

The Pancreatic Tumor Microenvironment Compensates for Loss of GOT2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.07.238766

N/A

0DataRank · unranked

4 citations

Lin Lin, Amy L. Myers, Yaqing Zhang, Jennifer A. Jiménez, Peter Sajjakulnukit +25 more

Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome

Nature Cancer(2022)10.1038/s43018-022-00348-3

N/A

0DataRank · unranked

92 citations

Matthew Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah +44 more

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.02.016

N/A

0DataRank · unranked

90 citations

Katelyn L. Donahue, Kristee L. Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar +22 more

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.12.978692

N/A

0DataRank · unranked

6 citations

Anna V. Mathew, Ilya Kovalenko, Anupama Pal, Ho‐Joon Lee, Daniel Peltier +12 more

Hyaluronic Acid Fuels Pancreatic Cancer Growth

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.14.293803

N/A

0DataRank · unranked

8 citations

Christopher J. Halbrook, Samuel A. Kerk, Stephanie Wisner, Daniel M. Kremer, Peter Sajjakulnukit +12 more

Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer

Oncogene(2022)10.1038/s41388-022-02385-9

N/A

0DataRank · unranked

30 citations

Shrila Rajendran, Brock A. Humphries, Alyssa C. Cutter, Ayşe J. Muñiz, Nicholas Ciavattone +12 more

NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function

Cell Reports(2022)10.1016/j.celrep.2022.111516

N/A

0DataRank · unranked

24 citations

Emily L. Yarosz, Anthony Andren, Li Zhang, Costas A. Lyssiotis, Cheong‐Hee Chang +1 more

Human Norovirus Triggers Primary B Cell Immune ActivationIn Vitro

mBio(2022)10.1128/mbio.00175-22

N/A

0DataRank · unranked

17 citations

Melissa K. Jones, Vivienne L. Young, Abimbola O. Kolawole, Irene A. Owusu, Mengrou Shan +10 more

ATP citrate lyase links increases in glycolysis to diminished release of vesicular suppressor of cytokine signaling 3 by alveolar macrophages

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2022)10.1016/j.bbadis.2022.166458

N/A

0DataRank · unranked

6 citations

Jennifer M. Speth, Hanna S. Hong, Loka R. Penke, Eric Zhang, Costas A. Lyssiotis +2 more

Opposing diet, microbiome and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.03.486886

N/A

0DataRank · unranked

10 citations

Marie Boudaud, Mathis Wolter, Celeste Alexander, Alessandro De Sciscio, Erica T. Grant +20 more

Arginase 1 is a key driver of immune suppression in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.21.497084

N/A

0DataRank · unranked

8 citations

Zeribe C. Nwosu, Wenting Du, Katelyn L. Donahue, Carlos E. Espinoza, Kristee Brown +14 more

Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome

Nature Cancer(2022)10.1038/s43018-022-00407-9

N/A

0DataRank · unranked

2 citations

Matthew Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah +44 more

Subset-specific mitochondrial and DNA damage shapes T cell responses to fever and inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.14.516478

N/A

0DataRank · unranked

2 citations

Joel H. Elasy, Channing Chi, Xiang Ye, Evan S. Krystoviak, Wasay Khan +15 more

Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II assembly and stability

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.27.501734

N/A

0DataRank · unranked

1 citations

Hanna S. Hong, Britton C Michmerhuizen, Anna-Lisa E. Lawrence, Li Zhang, Jason S. Knight +4 more

PINK1 supports colorectal cancer growth by regulating the labile iron pool

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.27.509713

N/A

0DataRank · unranked

0 citations

Nupur K. Das, Indrani Talukdar, Rashi Singhal, Cristina Castillo, Anthony Andren +4 more

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

Cancer & Metabolism(2020)10.1186/s40170-019-0202-2

N/A

0DataRank · unranked

52 citations

Lin Lin, Daniel M. Kremer, Cristovão M. Sousa, Cecilia Cotta‐Ramusino, Amy L. Myers +21 more

Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

Cell stem cell(2020)10.1016/j.stem.2020.06.005

N/A

0DataRank · unranked

63 citations

Yao-Chang Tsan, Fengbiao Mao, Daniel M. Kremer, Peter Sajjakulnukit, Li Zhang +12 more

High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions

Communications Biology(2020)10.1038/s42003-020-0988-z

N/A

0DataRank · unranked

90 citations

Ilya Kovalenko, Laura Goo, Hanna S. Hong, Samuel A. Kerk, Joel A. Yates +5 more

Uridine-derived ribose fuels glucose-restricted pancreatic cancer

Nature(2023)10.1038/s41586-023-06073-w

N/A

0DataRank · unranked

151 citations

Matthew H. Ward, Peter Sajjakulnukit, Pawan Poudel, Chanthirika Ragulan, Steven Kasperek +24 more

Transferrin Receptor‐Mediated Iron Uptake Promotes Colon Tumorigenesis

Advanced Science(2023)10.1002/advs.202207693

N/A

0DataRank · unranked

92 citations

Luke Villareal, Zhaoli Liu, Mohammad Haneef, Daniel Falcon, David Martin +13 more

Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice

Journal of Clinical Investigation(2023)10.1172/jci173034

N/A

0DataRank · unranked

83 citations

Yanling Zhang, Ryan A. Frieler, Anthony Andren, Sherri C. Wood, Daniel J. Tyrrell +7 more

Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis

eLife(2023)10.7554/elife.81289

N/A

0DataRank · unranked

71 citations

Lindsey N. Dzierozynski, Patrick B. Jonker, Roya AminiTabrizi, Hardik Shah, Rosa E. Menjivar +13 more

GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0437

N/A

0DataRank · unranked

63 citations

Zitong Zhao, Angelica Lin, John Z. Yang, Jie Xu, Kari Wilder-Romans +35 more

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis

Nature Communications(2023)10.1038/s41467-023-37924-9

N/A

0DataRank · unranked

48 citations

I-Lin Ho, Melinda Soeung, Er-Yen Yen, Jintan Liu, Yan Liang +22 more

Nutrient transporters: connecting cancer metabolism to therapeutic opportunities

Oncogene(2023)10.1038/s41388-023-02593-x

N/A

0DataRank · unranked

40 citations

Mun Gu Song, Marina Pasca di Magliano, Costas A. Lyssiotis, Sung Eun Kim, Zeribe C. Nwosu

Increased glucose availability sensitizes pancreatic cancer to chemotherapy

Nature Communications(2023)10.1038/s41467-023-38921-8

N/A

0DataRank · unranked

40 citations

Jonathan J. Hue, Ata Abbas, Hallie J. Graor, Omid Hajihassani, Mehrdad Zarei +22 more

PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104691

N/A

0DataRank · unranked

32 citations

Nupur K. Das, Indrani Talukder, Rashi Singhal, Cristina Castillo, Anthony Andren +4 more

Spotlight on GOT2 in Cancer Metabolism

OncoTargets and Therapy(2023)10.2147/ott.s382161

N/A

0DataRank · unranked

27 citations

Javier García‐Bermúdez, Kıvanç Birsoy, Mara H. Sherman, Yatrik M. Shah, Costas A. Lyssiotis +1 more

Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption

The Journal of Cell Biology(2023)10.1083/jcb.202206121

N/A

0DataRank · unranked

16 citations

Yi Tang, Xiao-Yan Li, Samuel A. Kerk, Costas A. Lyssiotis, Xiaoyue Sun +5 more

Iron promotes glycolysis to drive colon tumorigenesis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2023)10.1016/j.bbadis.2023.166846

N/A

0DataRank · unranked

11 citations

Luke Villareal, Lavanya Goodla, Hyeoncheol Kim, Daniel Falcon, Mohammad Haneef +10 more

An unexpected pathway to polyamines in pancreatic cancer

Molecular Cell(2023)10.1016/j.molcel.2023.05.014

N/A

0DataRank · unranked

8 citations

Costas A. Lyssiotis, Dominik Awad

Tissue-Specific Dependence of Th1 Cells on the Amino Acid Transporter SLC38A1 in Inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.13.557496

N/A

0DataRank · unranked

11 citations

Katherine L. Beier, Channing Chi, Darren R. Heintzman, Xiang Ye, Melissa M. Wolf +7 more

Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.19.533333

N/A

0DataRank · unranked

8 citations

Sam R. Holmstrom, Cristina Castillo, Carmine F. Palermo, Stephen A. Sastra, Anthony Andren +21 more

Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma

Research Square(2023)10.21203/rs.3.rs-3317816/v1

N/A

0DataRank · unranked

3 citations

Peter Sajjakulnukit, Andrew J. Scott, Caleb Heaslip, Anthony Andren, Kari Wilder-Romans +16 more

Sulfide oxidation promotes hypoxic angiogenesis and neovascularization

Physical Therapy Korea(2023)10.1101/2023.03.14.532677

N/A

0DataRank · unranked

0 citations

Victor Vitvitsky, Proud Seth, Harrison L. Hiraki, Hannah N. Bell, Anthony Andren +6 more

H 2 S preconditioning induces long-lived perturbations in O 2 metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.20.563353

N/A

0DataRank · unranked

0 citations

Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas A. Lyssiotis +2 more

Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer

Nature Cancer(2020)10.1038/s43018-020-00121-4

N/A

0DataRank · unranked

584 citations

Eileen S. Carpenter, Samantha B. Kemp, Veerin R. Sirihorachai, Stephanie The, Lawrence Delrosario +34 more

Sulfide oxidation promotes hypoxic angiogenesis and neovascularization

Nature Chemical Biology(2024)10.1038/s41589-024-01583-8

N/A

0DataRank · unranked

32 citations

Victor Vitvitsky, Apichaya Sethaudom, Rashi Singhal, Sumeet Solanki, Sydney Alibeckoff +8 more

Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation

Science Immunology(2024)10.1126/sciimmunol.adp3475

N/A

0DataRank · unranked

32 citations

Rachael C. Sinard, Emilie L. Fisher, Xiang Ye, Andrew R. Patterson, Joel H. Elasy +24 more

Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2322563121

N/A

0DataRank · unranked

23 citations

Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan +24 more

Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2318420121

N/A

0DataRank · unranked

21 citations

Chenxian Ye, Afia Nkansah, Thomas Decoville, Garrett M. Fogo, Peter Sajjakulnukit +8 more

Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection

Cell Reports(2024)10.1016/j.celrep.2024.114607

N/A

0DataRank · unranked

21 citations

Benjamin Klein, Michael J. McFadden, Norah K. Judge, Hannah E. Navarrete, Britton C Michmerhuizen +10 more

Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome

Journal of Clinical Investigation(2024)10.1172/jci169893

N/A

0DataRank · unranked

15 citations

Alyssa Harbaugh, Somanathapura K. NaveenKumar, Megan D. Radyk, Christine E. Rysenga, Kaitlyn Sabb +15 more

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

UNC Libraries(2024)10.17615/2caa-2659

N/A

0DataRank · unranked

24 citations

Daniel Zeitouni, Clint A. Stalnecker, Haoqiang Ying, Erik S. Knudsen, Guofang Zhang +26 more

H 2 S preconditioning induces long-lived perturbations in O 2 metabolism

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2319473121

N/A

0DataRank · unranked

17 citations

Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas A. Lyssiotis +2 more

ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection

Cell Reports(2024)10.1016/j.celrep.2024.114156

N/A

0DataRank · unranked

13 citations

Shayna E Jankowski, Hanna S Hong, Nicholas D Armas, Aditi I Vijendra, Mack B. Reynolds +14 more

Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma

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