Charles G. Drake

From the Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Henry Ford Health Systems, Detroit, MI; Carolina BioOncology Institute, Huntersville, NC; Washington University School of Medicine Siteman Cancer Center, St Louis, MO; and Medarex, Bloomsbury, NJ, and Milpitas, CA.

ORCID: 0000-0001-9610-3677

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data from Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer

(2023)10.1158/1078-0432.c.6530555

Top 100%

0DataRank

Top 100%0 citations

Wei Fu, Hao Wang, Jong C. Park, Theodore L. DeWeese, Phuoc T. Tran +14 more

Papers

Driven by 44 papers — median percentile 0. Top paper: “Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages”.

Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

Cell(2021)10.1016/j.cell.2021.04.038

N/A

9.0DataRank · unranked

379 citations

Nivedita Chowdhury, Scott M. Haake, Casey R. Ager, Vinson Wang, Lukas Vlahos +12 more

Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-1610

N/A

3.7DataRank · unranked

130 citations

Casey R. Ager, Aleksandar Obradović, Nivedita Chowdhury, Ali Ghasemzadeh, Wendy Mao +11 more

Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial

Nature Medicine(2023)10.1038/s41591-023-02284-w

N/A

3.0DataRank · unranked

106 citations

Angelo M. De Marzo, Tamara L. Lotan, Hao Wang, Sin Chan, Su Jin Lim +19 more

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3372

N/A

2.7DataRank · unranked

117 citations

Matthew C. Dallos, Marianna Zahurak, Alan W. Partin, Edward M. Schaeffer, Ashley E. Ross +14 more

A Phase 1 Trial of Durvalumab in Combination with Bacillus Calmette-Guerin (BCG) or External Beam Radiation Therapy in Patients with BCG-unresponsive Non-muscle-Invasive Bladder Cancer: The Hoosier Cancer Research Network GU16-243 ADAPT-BLADDER Study

European Urology(2023)10.1016/j.eururo.2023.01.017

N/A

2.1DataRank · unranked

57 citations

Michael A. O’Donnell, Jason A. Efstathiou, Marianna Zahurak, Gary L. Rosner, Jeff Smith +36 more

Perioperative nivolumab versus observation in patients with renal cell carcinoma undergoing nephrectomy (PROSPER ECOG-ACRIN EA8143): an open-label, randomised, phase 3 study

The Lancet Oncology(2024)10.1016/s1470-2045(24)00211-0

N/A

1.9DataRank · unranked

86 citations

Se-Eun Kim, Viraj A. Master, David H. McDermott, Lauren C. Harshman, Suzanne Cole +40 more

Nivolumab plus ipilimumab, with or without enzalutamide, in AR‐V7‐expressing metastatic castration‐resistant prostate cancer: A phase‐2 nonrandomized clinical trial

The Prostate(2021)10.1002/pros.24110

N/A

1.7DataRank · unranked

71 citations

Karim Boudadi, Wei Fu, Hao Wang, Rana Sullivan, Alice Jordan +12 more

Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer

Cancer Cell(2023)10.1016/j.ccell.2023.10.006

N/A

1.6DataRank · unranked

80 citations

Aleksandar Obradović, Matthew C. Dallos, Emerson A. Lim, Karie Runcie, Casey R. Ager +16 more

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Journal of Clinical Oncology(2010)10.1200/jco.2009.26.7609

N/A

1.2DataRank · unranked

2920 citations

Charles G. Drake, Ira Wollner, John D. Powderly, Joel Picus, William H. Sharfman +15 more

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Nature Biotechnology(2020)10.1038/s41587-019-0390-x

N/A

0.876DataRank · unranked

343 citations

Christine Sedlik, Faezzah Baharom, Yaling Zhu, Ramiro A. Ramirez-Valdez, Vincent Coble +25 more

Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-3570

N/A

0.806DataRank · unranked

215 citations

Diana Graves, Michael Korrer, Yu Wang, Sohini Roy, Abdullah Naveed +13 more

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2023-006782

N/A

0.776DataRank · unranked

21 citations

Mingxuan Zhang, Matthew G. Chaimowitz, Shruti Bansal, Somnath Tagore, Aleksandar Obradović +9 more

Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

Nature Cancer(2021)10.1038/s43018-021-00227-3

N/A

0.739DataRank · unranked

137 citations

Michael C. Haffner, Matthew G. Chaimowitz, Nivedita Chowdhury, Nicholas Venturini, Radhika A. Patel +14 more

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

Cell(2024)10.1016/j.cell.2024.01.008

N/A

0.689DataRank · unranked

98 citations

Alessandro Vasciaveo, Angelo Taglialatela, Xiao Chen, Tessa M. Firestone, Allison R. Hickman +28 more

Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-4476

N/A

0.631DataRank · unranked

66 citations

Wei Fu, Hao Wang, Jong C. Park, Theodore L. DeWeese, Phuoc T. Tran +14 more

Association between immunosuppressive cytokines and PSA progression in biochemically recurrent prostate cancer treated with intermittent hormonal therapy

The Prostate(2020)10.1002/pros.23948

N/A

0.629DataRank · unranked

13 citations

Samuel Pan, William D. Figg, Zoila A. Lopez‐Bujanda, Jonathan D. Strope, David H. Aggen +6 more

A DNA Hypomethylating Drug Alters the Tumor Microenvironment and Improves the Effectiveness of Immune Checkpoint Inhibitors in a Mouse Model of Pancreatic Cancer

Cancer Research(2020)10.1158/0008-5472.can-20-0285

N/A

0.614DataRank · unranked

59 citations

Jarwei Fang, Martha Salas, Catherine Do, Emily Hsu, Anna Zhukovskaya +9 more

Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators

Cancer Cell(2023)10.1016/j.ccell.2023.04.003

N/A

0.612DataRank · unranked

58 citations

Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Alina C. Iuga +16 more

Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0559

N/A

0.590DataRank · unranked

50 citations

Fanny Polesso, Julie N. Graff, Jessica E. Hawley, Alexis K. Smith, Arian Lundberg +35 more

Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa064

N/A

0.557DataRank · unranked

40 citations

Michael B. Atkins, Ziad Bakouny, Maria I. Carlo, Charles G. Drake, Eric Jonasch +15 more

Systematic, Protein Activity-based Characterization of Single Cell State

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.20.445002

N/A

0.483DataRank · unranked

24 citations

Aleksandar Obradović, Jeremy Worley, Xiangtian Tan, Andrew Howe, Pasquale Laise +4 more

Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor)

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2022-006262

N/A

0.449DataRank · unranked

19 citations

Brian F. Chapin, Sonali Jindal, Fei Duan, Sreyashi Basu, Shalini S. Yadav +16 more

Longitudinal Immune Profiling Reveals Unique Myeloid and T-cell Phenotypes Associated with Spontaneous Immunoediting in a Prostate Tumor Model

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0637

N/A

0.434DataRank · unranked

17 citations

Aleksandar Obradović, Juan Martín Arriaga, Matthew G. Chaimowitz, Andrea Califano, Cory Abate‐Shen +2 more

Divergent immune microenvironments in two tumor nodules from a patient with mismatch repair-deficient prostate cancer

npj Genomic Medicine(2024)10.1038/s41525-024-00392-1

N/A

0.360DataRank · unranked

10 citations

Laura A. Sena, Abderrahman Day, Benjamin Miller, Carly D. Miller, John R. Lozada +12 more

Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

eLife(2024)10.7554/elife.96812

N/A

0.346DataRank · unranked

7 citations

Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo Vignali, Ying Zheng +12 more

Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial

Cancer Prevention Research(2020)10.1158/1940-6207.capr-19-0450

N/A

0.345DataRank · unranked

9 citations

İbrahim Kulaç, Berrak Gümüşkaya, Javier Baena-Del Valle, Inés Benedetti, Fan Pan +13 more

PROSPER: Phase III randomized study comparing perioperative nivolumab versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN EA8143).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.tps5101

N/A

0.330DataRank · unranked

8 citations

Mäneka Puligandla, Mohamad E. Allaf, David F. McDermott, Charles G. Drake, Sabina Signoretti +15 more

Systematic Elucidation and Pharmacological Targeting of Tumor-Infiltrating Regulatory T Cell Master Regulators

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.22.481404

N/A

0.292DataRank · unranked

6 citations

Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Christopher M. Jackson +10 more

Myeloid Resistance is not Futile: Biomarkers of Immunotherapy in Bladder Cancer

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-1011

N/A

0.235DataRank · unranked

3 citations

Charles G. Drake

The PRIME-CUT study: A single-arm phase 2 study of ADT with PD-1 blockade and docetaxel in men with metastatic hormone-sensitive prostate cancer.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.e17089

N/A

0.165DataRank · unranked

2 citations

Matthew C. Dallos, Emerson A. Lim, Karie Runcie, Jianhua Hu, Israel Lowy +3 more

Single-Cell RNAseq Analysis Reveals Robust, Anti-PD-1-Mediated Increase of Immune Infiltrate in Metastatic Castration-Sensitive Prostate Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.06.490968

N/A

0.165DataRank · unranked

2 citations

Aleksandar Obradović, Matthew C. Dallos, Emerson A. Lim, Karie Runcie, Casey R. Ager +15 more

Impact of baseline serum IL-8 on metastatic hormone-sensitive (mHSPC) prostate cancer outcomes in the phase III CHAARTED trial (E3805).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.6_suppl.171

N/A

0.141DataRank · unranked

1 citations

Victoria Wang, Hidemi S. Yamamoto, Anis Hamid, Charles G. Drake, Michael A. Carducci +4 more

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.01.522340

N/A

0.104DataRank · unranked

1 citations

Mingxuan Zhang, Matthew G. Chaimowitz, Shruti Bansal, Aleksandar Obradović, Meri Rogava +7 more

Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.31.578284

N/A

0DataRank · unranked

2 citations

Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo Vignali, Ying Zheng +12 more

BCG invokes superior STING‐mediated innate immune response over radiotherapy in a carcinogen murine model of urothelial cancer

The Journal of Pathology(2021)10.1002/path.5830

N/A

0DataRank · unranked

20 citations

Aleksandar Obradović, Alok Kumar Singh, James L. Liu, Gregory Joice, Max Kates +11 more

Robust antigen-specific CD8 T cell tolerance to a model prostate cancer neoantigen

OncoImmunology(2020)10.1080/2162402x.2020.1809926

N/A

0DataRank · unranked

6 citations

Matthew G. Chaimowitz, Todd D. Armstrong, Jeremy B. Foote, Leisha A. Emens, Charles G. Drake +1 more

Impact of baseline serum IL‐8 on metastatic hormone‐sensitive prostate cancer outcomes in the Phase 3 CHAARTED trial (E3805)

The Prostate(2020)10.1002/pros.24074

N/A

0DataRank · unranked

21 citations

Victoria X. Wang, Anis Hamid, Gabriella Santone, Charles G. Drake, Michael A. Carducci +4 more

Data from Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses

(2023)10.1158/1078-0432.c.6530295

N/A

0DataRank · unranked

0 citations

Casey R. Ager, Aleksandar Obradović, Nivedita Chowdhury, Ali Ghasemzadeh, Wendy L. Mao +11 more

Data from Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer

(2023)10.1158/1078-0432.c.6530555

Top 100%

0DataRank

Top 100%0 citations

Wei Fu, Hao Wang, Jong C. Park, Theodore L. DeWeese, Phuoc T. Tran +14 more

Data from Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells

(2023)10.1158/2326-6066.c.6548576.v1

N/A

0DataRank · unranked

0 citations

Melissa Gamat, Joseph Seliski, Thomas Sawicki, Justin J. Jeffery, Leigh Ellis +4 more

A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target

Journal of Clinical Investigation(2020)10.1172/jci128672

N/A

0DataRank · unranked

137 citations

Thomas R. Nirschl, Daniel H. Hovelson, Robert J. Johnston, John Engelhardt, Mark Selby +15 more

PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric Tumorigenesis in Mice

Gastroenterology(2020)10.1053/j.gastro.2020.10.036

N/A

0DataRank · unranked

146 citations

Timothy Chu, Henrik Nienhüser, Zhengyu Jiang, Armando Del Portillo, Helen Remotti +7 more

The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function

Immunity(2024)10.1016/j.immuni.2024.07.003

N/A

0DataRank · unranked

44 citations

Ayush Pant, Wikum Dinalankara, John Choi, Aanchal Jain, Ryan T. Nitta +26 more

TGM4: an immunogenic prostate-restricted antigen

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2020-001649

N/A

0DataRank · unranked

27 citations

Aleksandar Obradović, Thomas R. Nirschl, Laura Crowley, Rodney Macedo, Alexandros Papachristodoulou +13 more

Charles G. Drake

Indexed papers

Top data-sharing exemplar

Papers